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6 Cards in this Set

  • Front
  • Back
What is bromocriptine used to treat?
dopamine receptor agonist - activates dopamine receptors - vasoconstrictive properties

used to treat Parkinson's

Inhibitory effect on prolactin release - effective in treating hyperprolactinemia
Why isn't carbonic anhydrase inhibiters a good diuretic? What is its main use?
It inhibits the Hydrogen needed for Na/H exchange early in the renal tubule. It is not stopped from leaving later in the tubule by different pumps, so very little Na is actually released via urine.

It is actually used in the chronic treatment of opeen angle glaucoma
What is a major difference in Loop and Thiazide side effects?
Loops get hypocalcemic

Thiazides get hypercalcemic
How does spironolactone and triamterene/amiloride differ?
spirono - inhibits Na reabsorption by inhibiting aldosterone

T/A - directly block Na/K exchange in the late distal tubule and collecting duct
What is the MOA of nitro?
vasodilation

reduce the volume of blood returned to the heart (preload). Decreased preolad decreases the amount of blood the heart will have to pump - less blood to pump, less work.

Reducing work reduces O2 demand.

With increasing dose, increasing effect on also the arterial structures - includes coronary arteries

Decreases peipheral vascular resistance (afterload) - allows heart to work less; decreased demand
What is the DOC for Pinzmetals angina?
Calcium Channel Blockers (Nifedipine, Verapamil)