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28 Cards in this Set

  • Front
  • Back
Opening and then closing of the Na+ channels
Depolarization phase in the generation of an action potential
All voltage-gated Na+ and K+ channels are closed.
The resting state of a neuron
Opening of potassium gates and the rushing in of K+
The repolarization phase in an action potential
The sodium channels remain opened
The absolute refractory period
Increased potassium efflux as a result of sluggish closure of the potassium gates
The phase in action potential known as the "after hyperpolarization"
Multiple sclerosis
The autoimmune disease that leads to destruction of the myelin sheaths in the CNS.
Saltatory conduction
The unique propagation process which occurs in myelinated axons
The all-or-none phenomenon
The situation where an action potential either happens completely or not at all
G-protein -linked receptors
Indirect synaptic responses which are complex, prolonged and often diffuse, as a result of the production of intracellular second messenger molecules
Rapid automatic responses to a stimulus in which the particular stimulus always produces the same motor response
Somatic nervous system
Conducts impulses from CNS to skeletal muscles
Autonomic nervous system
Conducts impulses from CNS to internal organ muscles
Central nervous system
Consists of brain and spinal cord
Peripheral nervous system
Consists of nerves carrying impulses to and from brain and spinal cord
Presynaptic calcium influx
Triggers neurotransmitter release
Synaptic cleft
Separates presynaptic terminal from postsynaptic membrane
Triggers voltage change in postsynaptic neuron
Binds to postsynaptic receptor/channel
Excites skeletal muscle
Main neurotransmitter of sympathetic nervous system
"Feel good" transmitter, deficient in Parkinson's disease
"Mood" transmitter, target of Prozac to relieve depression
Generally inhibitory, found throughout CNS
Peptides with inhibitory, opiate-like actions
Resting membrane level
-70 mV
Na+ concentration outside cell
150 mM
K+ concentration outside cell
5 mM
Protein concentration inside cell
150 mM