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12 Cards in this Set
- Front
- Back
- 3rd side (hint)
1st bones to ossify in 2nd month in utero
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clavicle
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main function
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growth and remodeling of bones
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specific function
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1. hematopoise (production of all blood cell except most lymphocytes
2. hematoclasia-destroy damaged cells 3. immunity-supplies stem lymphocytes and monocytes 4. osseus-bone remodeling |
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gross structure
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red marrow-active hematopoises (found in flat bones)
yellow marrow-contains fat cells (little hematopoiesis |
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shift from red to yellow marrow
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neonates-all red marrow
5-7 years (fat appers in shaft of long bones) 18-alomost all long bone marrow is yellow |
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microscopic structure
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vascular compartment
hemopoietic compartment |
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vascular compart
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nutrient arteries enter via nutrient foramina, empty into sinusoids in marrow cavity, then back out the same way
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predominate vascular element in marrow, have single endothelial cell layer w/ thin basement membrane, surrounded by reticular fibers and phagocytic cells
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sinusoids
important concept? |
walls frequently crossed by cells in transit
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hemopoietic compartment
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b/t sinusoids, contains 1. cells of hemopoitic lineage, CT cells (mast, macrophages, plasma, reticular)
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located against outer walls of sinusoids to provide access to platelet circulation
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megakarycytes
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erythrocyte location
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early-near sinusoids
late-against walls of sinusoid |
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granulocyte location
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early-furthest from sinusoids
late-against walls |
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