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8 Cards in this Set

  • Front
  • Back

Endochondral ossification

Bone develops by replacing hyaline cartilage


All bones, except clavicles, below the base of the skull form this way

Intramembranous ossification

Bones develop from a fibrous membrane


Forms the cranial bones of the skull and clavicles

Primary ossification center

Shaft region at center of hyaline cartilage

Postnatal bone growth

Long bones- interstitial growth of epiphyseal plate cartilage and its replacement by bone


All bones- grow in thickness by appositional growth

Proliferation zone (growth long bones)

Top side of stack next to resting zone


Cells quickly divide, pushing epiphysis away from diaphysis and lengthening the entire long bone

Hypertrophic zone (growth of lone bones)

Older chondrocytes in the stack


Enlarge leaving large interconnecting spaces

Calcification zone (growth of lone bones)

The sorrounding cartilage matrix calcifies and the chondrocytes die and deteriorate

Ossification zone (growth of lone bones)

Long slender spicules of calcified cartilage


Invaded by marrow elements, osteoclasts partly erode cartilage, osteoblasts cover them with new bone


Medullary cavity lengthens