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17 Cards in this Set

  • Front
  • Back
What is the WHO bone density criteria for osteoporosis?
BMD > or = to 2.5 standard deviation points less than young normal controls
What is the BMD for osteopenia?
Between 1 and 2 standard deviation points
How is Bone Mineral Density measured?
With Dual-energy x-ray absorptiometry (DXA) of the hip and vertebrae. (Note that if the patient has a collapsed vertebra, that the density scan may be abnormally high)

Measured as grams of mineral per square cm (g/cm2)
What is a limitation of the DXA scan?
It's based on an area measurement (not volume)
What is the T-score?
The T-score is a score that relates a person's BMD to young, normal adults of the same sex.
Doctors should not use T-scores for which types of patients?
Pre-menopausal women
Men under 50
Children
What is the prevalence of osteoporosis?
1 in 2 Caucasian women and 1 n 5 men will have an osteoporosis related fracture
What are some general indications for BMD testing in women and men?
Women 65 or older, men 70 or older.

Younger post-menopausal women and men 50-69 years with increased risk of osteoporosis

Adults with fractures after 50

and more...
Consider treatment for osteoporosis in patients with what?
Verebral/hip fractures
T-scores less than -2.5
Also check WHO 10 year fracture probability
Osteoporosis: non-medical interventions
Environmental modifications to decrease fall risk
Hip pad protectors
Weight bearing exercise
Factors to consider in management of osteoporosis
1. Weight bearing exercise
2. Reduction of risk factors
3. Nutrient intake
4. Pharmacologic therapies
Osteoporosis: risk factor reduction
1. Meds review: (lowest possible dose of steroids)
2. Smoking cessation
3. Treatment for alcohol abuse
4. Environmental safety
Why should calcium supplements be taken with food?
The calcium requires acid to become soluble
Osteoporosis: Pharmalogic therapies
- Estrogen
- SERMs (Selective Estrogen Receptor Modulators)
- Bisphosphonates
- Calcitonin
- Parathyroid Hormone Analog (1-34 PTH)
Bisphosphonates: AE
GI distress
Erosive esophagitis
Don't give what medication with kidney disease.
Fossamax
Widow's hump
Compression fracture of vertebrae