Bocock Uworld Week 3.4

Front 1

The most common primary immune deficiency?

Back 1

selective IgA deficiency

Front 2

secretory IgA deficiency +transfused blood products cause a...?

Back 2

fatal anaphylactic response

Front 3

Associated w/ a C1 compliment component deficiency?

Back 3

SLE

Front 4

delayed separation of the umbilical cord+recurrent cutaneous infections w/o pus?

Back 4

leukocyte adhesion deficiency

Front 5

The MCC of ELEVATED alpha fetoprotein levels?

Back 5

dating error or underestimation of gestational age

Front 6

Associated with DECREASED alpha fetoprotein?

Back 6

down's syndrome

Front 7

hypogonadism+small firm testicles+elongated limbs+gynecomastia

Back 7

klinefelter syndrome

Front 8

Genotype in pts with klinefelter syndrome?

Back 8

47XXY

Front 9

Produce testosterone in the male when stimulated by LH?

Back 9

leydig cells

Front 10

Seminiferous tubules are damaged and the interstitial leydig cells are unharmed in this condition?

Back 10

cryptorchidism

Front 11

Both the seminiferous tubules and the leydig cells are damaged in this condition?

Back 11

klinefelter syndrome

Front 12

cells that make sperm when stimulated by FSH?

Back 12

seminiferous tubules

Front 13

organ transplant recipient think...?

Back 13

immunocompromised

Front 14

What is the mode of transmission in adult listeria meningitis?

Back 14

contaminated food

Front 15

unique features of listeria?

Back 15

(1) can grow in cold temps
(2) tumbling motility

Front 16

First line rx for GAD whose onset of action takes several weeks?

Back 16

buspirone

Front 17

MOA of buspirone used in GAD?

Back 17

agonist at 5HT1A receptors

Front 18

result of a deletion or insertion of a single nucleotide?

Back 18

frameshift mutation

Front 19

Formula for filtration fraction?

Back 19

FF=GFR/RPF

note RPF=renal plasma flow

Front 20

What does constriction of the efferent arteriole do to GFR and filtration fraction?

Back 20

increases GRF and FF=GFR/RPF

Front 21

Should be administered to all minor children?

Back 21

emergent life saving therapy

Front 22

What proces of collagen formation is inhibited during vit c deficiency?

Back 22

collagen crosslinking

Front 23

Vit C is neccessary for the hydroxylation of proline and lysine residues in what molecule?

Back 23

procollagen

Front 24

The median nerve runs between what two muscles before entering the wrist and hand within the carpal tunnel?

Back 24

(1) flexor digitorium superficialis
(2) flexor digitorium profundus

Front 25

Injury to this nerve leads to "Claw Hand" deformity due to paralysis of the intrinsic muscles of the hand?

Back 25

ulnar nerve

Front 26

This disease is associated with niacin deficiency due to loss of dietary tryptophan?

Back 26

hartnup disease

Front 27

What is thr rx for Hartnup disease where there is a decrease in intestinal & renal absorption of tryptophan?

Back 27

niacin-B3

Front 28

Which is catalase positive....steptococcus or staphylococcus?

Back 28

staph

Front 29

Which organism causes impetigo and has late sequelae of rheumatic fever and APSGN?

Back 29

step pyrogenes (Beta hemolytic Group A strep)

Front 30

This org is alpha hemolytic and is optochin sensitive?

Back 30

strep pneumoniae

Front 31

This bug is beta hemolytic and bacitracin sensitive?

Back 31

strep pyrogenes (group A)

Front 32

Two functions of type two pneumocytes?

Back 32

(1) secrete surfactant
(2) regenerate alveolar epithelium following injury

Front 33

Associated with a diminished first heart sound with a apical holosystolic murmur radiating to the axilla?

Back 33

mitral regurgitaton

Front 34

Decreases regurgitant stroke volume(RSV) and increases forward stroke volume (FSV) in a pt with mitral regurg?

Back 34

decrease LV afterload w/ vasodilators

Front 35

The only gram+ bug that produces endotoxin?

Back 35

listeria

Front 36

This is when naked bacterial DNA fragments are uptaken and incorporated into another bacteria's genome?

Back 36

transformation

Front 37

Process where a bacteriophage carries a piece of DNA from one bacterium to another?

Back 37

transduction

Front 38

Bacterial DNA is transferred directly by cell to cell contact?

Back 38

conjugation

Front 39

Virulence factor of group A beta hemolytic strep that inhibits the activation of compliment and protects the bug from phagocytosis?

Back 39

M protein

Front 40

Enzyme responsible for step pyrogenes beta hemolytic activity?

Back 40

streptolysin O

Front 41

Group B streptococcus

Back 41

strep agalactiae

Front 42

3 MC pathogens associated with bacterial meningitis in infants< 3 months of age?

Back 42

(1) strep agalactiae (group B)
(2) Listeria monocytogenes
(3) E coli

Front 43

These bugs grow well in bile and 6.5% NaCL?

Back 43

enterococcus

Front 44

This bug is the MCC of bacterial meningitis and pneumonia in adults....& otitis media in children?

Back 44

strep pneumoniae (pneumococcus)

Front 45

enzyme that breaks down hydrogen peroxide?

Back 45

catalase

Front 46

Of the three staph species...staph aureus, epidermidis, and saprophyticus...which one is coagulase positive?

Back 46

stap aureus

Front 47

Coagulase + gram + cocci in clusters?

Back 47

staph aureus

Front 48

This enzyme of staph aureus activates prothrombin causing clots?

Back 48

coagulase