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18 Cards in this Set
- Front
- Back
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Cells with enlarged nuclei and perinuclear halos seen in LSIL are called what?
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koilocytes
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neoplasia
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general process of new growth
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neoplasm
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a new growth
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tumorigenesis
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mechanisms underlying tumor formation
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tumors of the squamous epithelium
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benign - squamous papilloma
malignant - squamous cell carcinoma |
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tumors of the glandular epithelium
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benign - adenoma
malignant - adenocarcinoma |
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tumors of the surface epithelium
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benign - papilloma
malignant - papillary carcinoma |
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differences in benign vs malignant tumors (4)
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differentiation, growth, local invasion, metastasis
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What is CIN and what does it stand for?
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cervical intraepithelial neoplasia - a ranking system for cervical cancer precursor lesions
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what is the 3 step model of cervical carcinogenesis?
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infection with high-risk HPV, persistence of infection with progression to a precursor lesion, invasion of surrounding tissues
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what types of HPV are most commonly responsible for cancer?
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16* and 18
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describe how HPV genes extend the life of the cell
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HPV infects what kinds of epithelial cells?
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basal keratinocytes
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high nuclear-cytoplasmic ratio and mitotic figures are characteristic of what?
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HSIL
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What is the most likely outcome of any SIL
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regression (only 1.7% progress to cancer)
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nests of tumor cells that have invaded the stroma are characteristics of what?
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invasive squamous cell carcinoma
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____________ is the most important prognostic factor in cervical cancer
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staging
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HSIL classifies as stage __
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0
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