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11 Cards in this Set
- Front
- Back
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What is Zero order kinetics?
3 drugs that are zero order? |
When the amt of drug eliminated per unit time is CONSTANT regardless of the dose
PEA (is round like a 0) Phenytoin Ethanol ASA |
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What is First order kinetics?
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When the amt of drug eliminated per unit time is PROPORTIONAL to the concentration of that drugs
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Weak acids will get trapped in basic environments bc they will lose their H+. How should you treat OD?
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Give HCO3
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Weak bases will get trapped in acidic environments bc they gain an H+. How should you tx OD?
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Ammonium Chloride
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3 Types of phase I RXNs?
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Reduction
Oxidation Hydrolysis |
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3 Types phase II RXNS?
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GAS
Glucuronidation Acetylation Sulfation |
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What does this describe:
Dose that is lethal to 50% of pop Dose @ which Rx is effective for 50% population |
LD50
ED50 |
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What is the equation for TI (Therapeutic Index)
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LD50 / ID50
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Is a high or low TI a good thing?
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High TI
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SEE FA 262 for ANS Pathways
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SEE FA 262 for ANS Pathways
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SEE FA 263 for diff actions of diff receptors
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SEE FA 263 for diff actions of diff receptors
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