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130 Cards in this Set

  • Front
  • Back
Acitinic (solar) keratosis
Precursor to squamous cell carcinoma
Acute gastric ulcer associated with CNS injury
Cushing ulcer (inc ICP stimulates vagal gastric secretion)
Acute gastric ulcer associated with severe burns
Curling's ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
Alternating areas of transmural inflammation and normal colon
Skip lesions (Crohn's disease)
Aneurysm, dissecting
Hypertension
Aortic aneurysm, abdominal and descending aorta
Atherosclerosis
Aortic anueyrsm, ascending
Tertiary syphillis, Marfan's syndrome
Atrophy of the mammillary bodies
Wernicke's encephalopathy (thiamine deficiency causing ataxia, opathalmoplegia, and confusion)
Autosplenectomy (fibrosis and shrinkage)
Sickle cell anemia (HbS)
Bacteria associated with stomach cancer
H. pylori
Bacterial meningitis (adult and eldelry)
N. meningiditis, S. penumo
Bacterial meningitis (newborns and kids)
GBS (newborns), S. pneumo/N. meningitis (kids)
Benign melanocytic nevus
Spitz nevus (most common in first two decades)
Bleeding disorder with Gp1b deficiency
Bernard-Soulier disease (defect in platelet adhesion to von Willebrand's factor)
Brain tumor (adults)
Supratentorial: mets > astrocytoma (including GBM) > meningioma > schwannoma
Brain tumor (kids)
Infratentorial: medulloblastoma (cerebellum) or supratentorial: craniophyarngioma (cerebrum)
Breast cancer
Infiltrating ductal carcinoma (invasive ductal carcinoma)
Breast mass
1. fibrocytstic change
2. carcinoma (in postmenopausal women)
Breast tumor (benign)
Fibroadenoma
Cardiac Primary Tumor (kids)
Rhabdomyoma (tuberous sclerosis)
Cardiac manifestations of lupus
Libman-Sacks endocarditis (nonbacterial, affecting mitral)
Cardiac tumor (adults)
1. mets
2. primary myxoma (4:1 left to right atrium, ball and valve)
Cerebellar tonsilar herniation
Chiair malformation (often presents with progressive hydrocephalus or syringomelia)
Chronic arrhythmia
Atrial fibrillation (associated w/ high risk of emboli)
Chronic atrophic gastritis (autoimmune)
Predisposition to gastric carcinoma (can also cause pernicious anemia)
Clear cell adenocarcinoma of the vagina
DES exposure in utero
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
Congenital cardiac anomly
VSD
Congenital conjugated hyperbilirubinemia (black liver)
Dubin Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)
Constrictive pericarditis in developing world
TB
Coronary artery involved in thrombosis
LAD>RCA>LCA
Cretinism
Iodine deficit/hypothyroidism
Cushing's syndrome
1. corticosteroid therapy
2. excess ACTH secretion by pituitary
Cyanosis (early; less common)
Tetraollogy of fallot, transposition of great vessels, truncus arteriosus
Cyanosis (late; more common)
VSD, ASD, PDA
Death in CML
Blast crisis
Death in SLE
Lupus nephropathy
Dementia
1. Alzheimer's disease
2. Multiple infarcts
Demyelinating disease in young women
Multiple sclerosis
DIC
Gram negative sepsis, obstetric complications, cancer, burn trauma (STOP making new thrombi)
Dietary deficit
Iron
Diverticulum in pharynx
Zenker's diverticulum (diagnosed by barium swallow)
Ejection click
Aortic/pulmonic stenosis
Esophageal cancer
Squamous cell carcinoma (worldwide); adenocarcinoma (US)
Food poisoining (exotoxin mediated)
S. aureus, B. cereus
Glomerulonephritis (adults)
Berger's disease (IgA nephropathy)
Gynecologic malignancy
Endometrial carcinoma (most common)
Heart murmur, congenital
Mitral valve prolapse
Heart valve in bacterial endocarditis
Mitral (rheumatic fever), tricuspid (IV drug abuse), aortic (2nd affected in rheumatic fever)
Helminth infection (US)
1. enterobius vermicularis
2. ascaris lumbricoides
Hematoma - epidural
Rupture of middle meningeal artery (crescent shape)
Hematoma - subdural
Rupture of bridging veins (trauma; lentiform shaped)
Hemachromatosis
Multiple blood transufions or hereditary HFE mutation (can result in CHF, "bronze diabetes" and inc risk of hepatocellular carcinoma)
Hepatocellular carcinoma
Cirrhotic liver (often associated with hep B and C); inc alpha fetoprotein
Hereditary bleeding disorder
von Willebrand's disease
Hereditary harmless jaundice
Gilbert's syndrome (benign congenital unconjugated hyperbilirubinemia)
HLA B27
Ankylosing spondylitis, Reiter's syndrome, ulcerative colitis, psoriasis (PAIR)
HLA DR3 or DR4
Diabetes mellitus type 1, Rheumatoid arthritis, SLE
Holosytolic murmur
VSD, tricuspid regurgitation, mitral regurgitation
Hypercoagulability, endothelial damage, blood stasis
Virchow's triad (results in venous thrombosis)
Secondary hypertension
Renal disease
Hypoparathyroidism
Thryoidectomy
Hypopituitarism
Pituitary adenoma (usually benign tumor)
Infection secondary to blood transfusion
Hep C
Kidney stones
1. calcium = radiopaque
2. struvive (ammonium) = radiopaque (formed by urease positive organisms such as P. vulgaris or staph)
3. uric acid = radiolucent
Late cyanotic shunt (uncorrected L --> R becomes R --> L)
Eisemenger's syndrome (caused by ASD, VSD, PDA; results in pulmonary hypertension/polycythemia)
Liver disease
Alcoholic cirrhosis
Lysosomal storage disease
Gaucher's disease
Male cancer
Prostatic carcinoma
Malignant associated with noninfectious fever
Hodgkin's lympoma
Malignant skin tumor
basal cell carcinoma (rarely mets)
Mental retardation
1. FAS
2. Down's
3. Fragile X
Metastasis to bone
Breast, lung, thyroid, prostate, kidney
Metastasis to brain
Lung, breast, skin (melanoma), kidney (renal cell carcinoma), GI
Metastasis to liver
Colon, gastric, pancreatic, breast and lung carcinomas
Mitral valve stenosis
Rheumatic heart disease
Mixed (UMN and LMN) motor neuron disease
ALS
Myocarditis
Coxsackie B
Neoplasm (kids)
1. ALL
2. Cerebellar astrocytoma
Nephrotic syndrome (adults)
Membranous glomerulonephritis
Nephrotic syndrome (kids)
minimal change disease (associated with infections/vaccinations; treat with corticosteroids) --> podocyte fusion
Nosocomial pneumonia
Klebsiella, E. coli, pseudomonas aeruginosa, S. aureus
Obstruction of male urinary tract
BPH
Opening snap
Mitral stenosis
Opportunistic infections in AIDS
Pneumocystis jiroveci (formely carinii) penumonia
Osteomyelitis
S. aureus
Osteomyelitis in sickle cell disease patients
Salmonella
Osteomyelitis with IV drug use
Pseudomonas, S. aureus
Ovarian metastasis from gastric carcinoma or breast cancer
Krukenberg tumor (mucin secreting signet ring cells)
Ovarian tumor (benign)
Serous cystadenoma
Ovarian tumor (malignant)
Serous cystadenocarcinoma (CA 125)
Pancreatitis (acute)
Gallstones, alcohol
Pancreatitis (chronic)
Alcohol (adults), cystic fibrosis (kids)
Patient with ALL/CLL/AML/CML demographics
ALL: child
CLL: adult >60
AML: adult >60
CML: adult 35-50
Pelvic inflammatory disease
N. gonorrhea (monoarticular arthritis) + chlamydia
Philadelphia chromosome t(9;22) (bcr-abl)
CML (may sometimes be associated with ALL/AML)
Pituitary tumor
1. Prolactinoma
2. Somatotrophic "acidophilic" adenoma
Pituitary adenoma
Turners syndrome (XO)
Primary bone tumor (adults)
Multiple myeloma
Primary hyperaldosteronism
Adenoma of adrenal cortex
Primary hyperparathyroidism
1. Adenomas
2. hyperplasia
3. carcinoma
Primary liver cancer
Hepatocellular carcinoma (chronic hepatitis, cirrhosis, hemochromatosis, alpha one antitrypsin)
Pulmonary hypertension
COPD
Recurrent inflammation/thrombosis of small/medium vessels in extremities
Buerger's disease (strongly associated w/ tobacco)
Renal tumor
Renal cell carcinoma: associated with von Hippel Lindau and adult polycystic kidney disease; paraneoplastic syndrome (erythropoietin, renin, PTH, ACTH)
Right failure due to a pulmonary cause
Cor pumonale
S3 (protodiastolic gallop)
Inc ventricular filling (L --> R shunt, mitral regurg, LV failure CHF)
S4 (presystolic gallop)
Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)
Secondary hyperparathyroidism
hypocalcemia of chronic kidney disease
Sexually transmitted disease
Chlamydia (usually coinfected with gonorrhea)
SIADH
Small cell carcinoma of the lung
Site of diverticula
Sigmoid colon
Sites of atherosclerosis
Abdominal aorta > coronary > popliteal > carotid
Stomach cancer
Adenocarcinoma
t (14;18)
Follicular lymphomas (bcl 2 activation)
t (8;14)
Burkitt's lympohoma (c myc activation)
t (9;22)
Philadelphia chromosome, CML (bcr abl hybrid)
Temporal arteritis
Risk of ipsilateral blindeness due to thrombosis of opathalmmic artery; polymalgia rheumatica, inc ESR
Testicular tumor
seminoma
Thyroid cancer
papillary carcinoma (Orphan Annie bodies)
Tumor in women
Leiomyoma (estrogen dependent)
Tumor of infancy
Hemangioma (usually regresses spontaneously by childhood)
Tumor of the adrenal medulla (adults)
Pheochromocytoma (usually benign)
Tumor of the adrenal medulla (kids)
Neuroblastoma (malignant) Homer wright rosettes
Types of hodkin's
nodular sclerosis (vs mixed cellularity, lymphocytic predominance, lymphocytic depletion)
Types of non hodgkin's
Diffuse large cell
UTI
E. coli, Staph saprophyticus (young women)
Viral encephalitis affecting temporal lobe
HSV
Vitamin Deficiency (US)
Folic acid (pregnant women are at high risk; body stores only 3 - 4 month supply; prevents NT defects)
t(11;12)
Ewing's sarcoma