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130 Cards in this Set
- Front
- Back
Acitinic (solar) keratosis
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Precursor to squamous cell carcinoma
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Acute gastric ulcer associated with CNS injury
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Cushing ulcer (inc ICP stimulates vagal gastric secretion)
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Acute gastric ulcer associated with severe burns
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Curling's ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
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Alternating areas of transmural inflammation and normal colon
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Skip lesions (Crohn's disease)
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Aneurysm, dissecting
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Hypertension
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Aortic aneurysm, abdominal and descending aorta
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Atherosclerosis
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Aortic anueyrsm, ascending
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Tertiary syphillis, Marfan's syndrome
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Atrophy of the mammillary bodies
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Wernicke's encephalopathy (thiamine deficiency causing ataxia, opathalmoplegia, and confusion)
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Autosplenectomy (fibrosis and shrinkage)
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Sickle cell anemia (HbS)
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Bacteria associated with stomach cancer
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H. pylori
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Bacterial meningitis (adult and eldelry)
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N. meningiditis, S. penumo
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Bacterial meningitis (newborns and kids)
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GBS (newborns), S. pneumo/N. meningitis (kids)
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Benign melanocytic nevus
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Spitz nevus (most common in first two decades)
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Bleeding disorder with Gp1b deficiency
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Bernard-Soulier disease (defect in platelet adhesion to von Willebrand's factor)
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Brain tumor (adults)
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Supratentorial: mets > astrocytoma (including GBM) > meningioma > schwannoma
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Brain tumor (kids)
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Infratentorial: medulloblastoma (cerebellum) or supratentorial: craniophyarngioma (cerebrum)
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Breast cancer
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Infiltrating ductal carcinoma (invasive ductal carcinoma)
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Breast mass
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1. fibrocytstic change
2. carcinoma (in postmenopausal women) |
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Breast tumor (benign)
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Fibroadenoma
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Cardiac Primary Tumor (kids)
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Rhabdomyoma (tuberous sclerosis)
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Cardiac manifestations of lupus
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Libman-Sacks endocarditis (nonbacterial, affecting mitral)
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Cardiac tumor (adults)
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1. mets
2. primary myxoma (4:1 left to right atrium, ball and valve) |
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Cerebellar tonsilar herniation
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Chiair malformation (often presents with progressive hydrocephalus or syringomelia)
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Chronic arrhythmia
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Atrial fibrillation (associated w/ high risk of emboli)
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Chronic atrophic gastritis (autoimmune)
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Predisposition to gastric carcinoma (can also cause pernicious anemia)
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Clear cell adenocarcinoma of the vagina
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DES exposure in utero
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Congenital adrenal hyperplasia, hypotension
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21-hydroxylase deficiency
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Congenital cardiac anomly
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VSD
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Congenital conjugated hyperbilirubinemia (black liver)
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Dubin Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)
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Constrictive pericarditis in developing world
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TB
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Coronary artery involved in thrombosis
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LAD>RCA>LCA
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Cretinism
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Iodine deficit/hypothyroidism
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Cushing's syndrome
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1. corticosteroid therapy
2. excess ACTH secretion by pituitary |
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Cyanosis (early; less common)
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Tetraollogy of fallot, transposition of great vessels, truncus arteriosus
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Cyanosis (late; more common)
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VSD, ASD, PDA
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Death in CML
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Blast crisis
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Death in SLE
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Lupus nephropathy
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Dementia
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1. Alzheimer's disease
2. Multiple infarcts |
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Demyelinating disease in young women
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Multiple sclerosis
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DIC
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Gram negative sepsis, obstetric complications, cancer, burn trauma (STOP making new thrombi)
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Dietary deficit
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Iron
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Diverticulum in pharynx
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Zenker's diverticulum (diagnosed by barium swallow)
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Ejection click
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Aortic/pulmonic stenosis
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Esophageal cancer
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Squamous cell carcinoma (worldwide); adenocarcinoma (US)
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Food poisoining (exotoxin mediated)
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S. aureus, B. cereus
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Glomerulonephritis (adults)
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Berger's disease (IgA nephropathy)
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Gynecologic malignancy
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Endometrial carcinoma (most common)
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Heart murmur, congenital
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Mitral valve prolapse
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Heart valve in bacterial endocarditis
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Mitral (rheumatic fever), tricuspid (IV drug abuse), aortic (2nd affected in rheumatic fever)
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Helminth infection (US)
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1. enterobius vermicularis
2. ascaris lumbricoides |
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Hematoma - epidural
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Rupture of middle meningeal artery (crescent shape)
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Hematoma - subdural
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Rupture of bridging veins (trauma; lentiform shaped)
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Hemachromatosis
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Multiple blood transufions or hereditary HFE mutation (can result in CHF, "bronze diabetes" and inc risk of hepatocellular carcinoma)
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Hepatocellular carcinoma
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Cirrhotic liver (often associated with hep B and C); inc alpha fetoprotein
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Hereditary bleeding disorder
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von Willebrand's disease
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Hereditary harmless jaundice
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Gilbert's syndrome (benign congenital unconjugated hyperbilirubinemia)
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HLA B27
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Ankylosing spondylitis, Reiter's syndrome, ulcerative colitis, psoriasis (PAIR)
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HLA DR3 or DR4
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Diabetes mellitus type 1, Rheumatoid arthritis, SLE
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Holosytolic murmur
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VSD, tricuspid regurgitation, mitral regurgitation
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Hypercoagulability, endothelial damage, blood stasis
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Virchow's triad (results in venous thrombosis)
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Secondary hypertension
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Renal disease
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Hypoparathyroidism
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Thryoidectomy
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Hypopituitarism
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Pituitary adenoma (usually benign tumor)
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Infection secondary to blood transfusion
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Hep C
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Kidney stones
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1. calcium = radiopaque
2. struvive (ammonium) = radiopaque (formed by urease positive organisms such as P. vulgaris or staph) 3. uric acid = radiolucent |
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Late cyanotic shunt (uncorrected L --> R becomes R --> L)
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Eisemenger's syndrome (caused by ASD, VSD, PDA; results in pulmonary hypertension/polycythemia)
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Liver disease
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Alcoholic cirrhosis
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Lysosomal storage disease
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Gaucher's disease
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Male cancer
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Prostatic carcinoma
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Malignant associated with noninfectious fever
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Hodgkin's lympoma
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Malignant skin tumor
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basal cell carcinoma (rarely mets)
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Mental retardation
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1. FAS
2. Down's 3. Fragile X |
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Metastasis to bone
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Breast, lung, thyroid, prostate, kidney
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Metastasis to brain
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Lung, breast, skin (melanoma), kidney (renal cell carcinoma), GI
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Metastasis to liver
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Colon, gastric, pancreatic, breast and lung carcinomas
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Mitral valve stenosis
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Rheumatic heart disease
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Mixed (UMN and LMN) motor neuron disease
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ALS
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Myocarditis
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Coxsackie B
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Neoplasm (kids)
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1. ALL
2. Cerebellar astrocytoma |
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Nephrotic syndrome (adults)
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Membranous glomerulonephritis
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Nephrotic syndrome (kids)
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minimal change disease (associated with infections/vaccinations; treat with corticosteroids) --> podocyte fusion
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Nosocomial pneumonia
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Klebsiella, E. coli, pseudomonas aeruginosa, S. aureus
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Obstruction of male urinary tract
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BPH
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Opening snap
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Mitral stenosis
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Opportunistic infections in AIDS
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Pneumocystis jiroveci (formely carinii) penumonia
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Osteomyelitis
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S. aureus
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Osteomyelitis in sickle cell disease patients
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Salmonella
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Osteomyelitis with IV drug use
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Pseudomonas, S. aureus
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Ovarian metastasis from gastric carcinoma or breast cancer
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Krukenberg tumor (mucin secreting signet ring cells)
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Ovarian tumor (benign)
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Serous cystadenoma
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Ovarian tumor (malignant)
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Serous cystadenocarcinoma (CA 125)
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Pancreatitis (acute)
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Gallstones, alcohol
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Pancreatitis (chronic)
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Alcohol (adults), cystic fibrosis (kids)
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Patient with ALL/CLL/AML/CML demographics
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ALL: child
CLL: adult >60 AML: adult >60 CML: adult 35-50 |
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Pelvic inflammatory disease
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N. gonorrhea (monoarticular arthritis) + chlamydia
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Philadelphia chromosome t(9;22) (bcr-abl)
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CML (may sometimes be associated with ALL/AML)
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Pituitary tumor
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1. Prolactinoma
2. Somatotrophic "acidophilic" adenoma |
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Pituitary adenoma
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Turners syndrome (XO)
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Primary bone tumor (adults)
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Multiple myeloma
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Primary hyperaldosteronism
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Adenoma of adrenal cortex
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Primary hyperparathyroidism
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1. Adenomas
2. hyperplasia 3. carcinoma |
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Primary liver cancer
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Hepatocellular carcinoma (chronic hepatitis, cirrhosis, hemochromatosis, alpha one antitrypsin)
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Pulmonary hypertension
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COPD
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Recurrent inflammation/thrombosis of small/medium vessels in extremities
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Buerger's disease (strongly associated w/ tobacco)
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Renal tumor
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Renal cell carcinoma: associated with von Hippel Lindau and adult polycystic kidney disease; paraneoplastic syndrome (erythropoietin, renin, PTH, ACTH)
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Right failure due to a pulmonary cause
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Cor pumonale
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S3 (protodiastolic gallop)
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Inc ventricular filling (L --> R shunt, mitral regurg, LV failure CHF)
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S4 (presystolic gallop)
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Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)
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Secondary hyperparathyroidism
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hypocalcemia of chronic kidney disease
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Sexually transmitted disease
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Chlamydia (usually coinfected with gonorrhea)
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SIADH
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Small cell carcinoma of the lung
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Site of diverticula
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Sigmoid colon
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Sites of atherosclerosis
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Abdominal aorta > coronary > popliteal > carotid
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Stomach cancer
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Adenocarcinoma
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t (14;18)
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Follicular lymphomas (bcl 2 activation)
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t (8;14)
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Burkitt's lympohoma (c myc activation)
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t (9;22)
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Philadelphia chromosome, CML (bcr abl hybrid)
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Temporal arteritis
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Risk of ipsilateral blindeness due to thrombosis of opathalmmic artery; polymalgia rheumatica, inc ESR
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Testicular tumor
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seminoma
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Thyroid cancer
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papillary carcinoma (Orphan Annie bodies)
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Tumor in women
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Leiomyoma (estrogen dependent)
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Tumor of infancy
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Hemangioma (usually regresses spontaneously by childhood)
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Tumor of the adrenal medulla (adults)
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Pheochromocytoma (usually benign)
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Tumor of the adrenal medulla (kids)
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Neuroblastoma (malignant) Homer wright rosettes
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Types of hodkin's
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nodular sclerosis (vs mixed cellularity, lymphocytic predominance, lymphocytic depletion)
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Types of non hodgkin's
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Diffuse large cell
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UTI
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E. coli, Staph saprophyticus (young women)
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Viral encephalitis affecting temporal lobe
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HSV
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Vitamin Deficiency (US)
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Folic acid (pregnant women are at high risk; body stores only 3 - 4 month supply; prevents NT defects)
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t(11;12)
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Ewing's sarcoma
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