Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
What type of chromatin is condensed and transcriptionally inactive?
Less condensed and active? |
Heterochromatin
Euchromatin HeteroChromatin = Highly Condensed |
|
|
How many rings do purines have? What are the purine nucleotides?
|
Two rings (remember, one pie --> pyrimidine)
A and G PURe As Gold |
|
|
How many rings do pyrimidines have? What are the pyrimidine nucleotides?
|
One ring (one pie)
C, U, T CUT the PY (pie) |
|
|
Xeroderma pigmentosum
|
nucleotide excision repair is mutated, can't repair thymine dimers
results in dry skin with melanoma and other cancers, "children of the night" |
|
|
HNPCC
|
mismatch repair (of DNA) is mutated
|
|
|
Beta thalassemia
|
alternate mRNA splicing
|
|
|
how does tetracycline work?
|
binds the 30s subunit to prevent attachment of aminoacyl-tRNA (the charging of the RNA)
|
|
|
how do aminoglycosides work?
|
inhibit formation of the initiation complex during protein formation, cause misreading of mRNA
|
|
|
how does chloramphenicol work?
|
inhibit 50s peptidyltransferase
|
|
|
how do macrolides work?
|
bind 50s, block translocation of RNA
|
