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9 Cards in this Set
- Front
- Back
What is and how do you see the structure of Amyloid?
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Its a Beta-Pleated sheet seen by apple-green birefringence of Congo Red Stain seen under polarized light
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7 Types of Amyloidosis?
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Primary
Secondary Senile Cardiac DM type 2 Medullary Carcinoma of Thyroid Alzheimer's Dialysis-associated |
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7 Types of Amyloidosis and their associated protein?
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Primary - AL
Secondary - AA Senile Cardiac - Transthyretin DM Type 2: Amylin Medullary Carcinoma of Thyroid: A-CAL Alzheimer's: Beta-amyloid Dialysis-ass: Beta2-microglobulin |
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7 Types of Amyloidosis and where they amyloid is derived from?
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Primary: Ig Light Chains
Secondary: Serum Amyloid-associated Protein (SAA) Senile cardiac: AF DM: AE Med. Carcinoma of Thyroid: Calcitonin Alz: Amyloid Precursor Protein Dialysis-ass: MHC Class I proteins |
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Disease associated w/ Primary Amyloidosis?
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Multiple Myeloma
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Disease associated w/ Secondary Amyloidosis?
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Chronic Inflammatory Diseases
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2 main types of Shock?
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Hypovolemic/cardiogenic
Septic |
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Pathogenesis of 2 types of shock?
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Hypovolemic: Low-output failure
Septic: high-output failure; high mixed venous pressure |
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Sx's of the 2 types of shock?
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HYPOVOLEMIC
cold clammy low CO Inc TPR SEPTIC hot dilated arterioles dec TPR |