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33 Cards in this Set
- Front
- Back
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describe Hemophilia A
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X linked recessive clotting disorder resulting in the deficiency of factor 8
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How are coag profiles affected by Hemophilia A?
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Ptt is significantly prolonged in severe forms
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Tx for hemophilia B
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Factor IX concentrate
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Tx for hemophilia A
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Factor VIII concentrat
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Define Hemophilia B
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X linked recessive coag disorder caused by a deficiency of factor IX
AKA- Christmas disease |
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Define cerebral palsy
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a varied set of symptoms that occur due to lesions of the brain that occur during early stages of development
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What is the most common type of CP?
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skeletal muscle spacity
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What meds are given to tx CP?
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(these meds tx spacity)
dantrolene, botox, baclofen |
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anesthetic considerations for pt with CP
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increased risk of reflux
weak airway muscles susceptible to hypothermia pt should be wide awake to extubate MAC is decreased, emergence is longer |
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what is the expected reaction of a pt with CP to succs?
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normal response- hyperkalemia or MH are not expected
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How do pts with CP respond to NDMRs
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pts may be resistant
(d/t long term use of antiseizure meds) |
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what is the treatment for uremic bleeding
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DDAVP or cryoprecipitate
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How are coag studies affected in uremic bleeding
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Pt, PTT, and platelet count are normal, bleeding time is prolonged
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What lab values are diagnostic of type 1 diabetes?
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random blood glucose >200 & HA1C >7.0%
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How is insulin metabolized?
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liver/ kidneys
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normal insulin production per day
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40-50 units/day
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Name the short acting insulins
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Human regular (lasts 5-8 hrs)
Lispro (Humalog) (lasts 3-6 hours) Aspart (novolog) (lasts 3-6 hours) |
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Name the intermediate acting insulins
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Human NPH
Lente both last 10-20 hours |
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Name the long acting insulins
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Ultralente (24-48 hours)
Glargine (Lantus) (24 hours) |
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How do alpha glucosidase inhibitors work?
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decrease postprandial glucose absorption
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How do sulfonylureas work?
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increase insulin secretion
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How do thiazolinediones and metformin work?
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enhance tissue sensitivity to insulin
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s/s of hypoglycemia
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sympathetic response- hypertension, tachycardia, diaphoresis & lacrimation
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How do increased glucose levels cause end organ damage
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hyperglycemia causes vasodilation prevention the organs from protecting themselves from hypertension by increasing the SVR in organs
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what is the chief indicator that diabetes has progressed to advanced glomerulonephritis
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proteinuria
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what are signs of autonomic neuropathy?
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lack of orthostatic changes in heart rate, lack of sweating, impotence and early saitey
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hyperglycemia is associated with what change in sodium levels?
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hyponatremia due to dilution
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diagnostic features of HHNK?
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glucose >600
pH >7.3 Bicarb >15 Serum osmo >350 |
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diagnostic features of DKA?
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glucose >300
hypovolemia hyponatremia pH <7.3 bicarb <18 osmo <320 ketonemia |
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electrolyte abnormalities associated with DKA
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hyperglycemia
hyponatremia hypophosphatemia hypokalemia hypomagnesemia |
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What glaucoma med prolongs the effects of succs
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echotiophate
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normal intraocular pressure
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10-21mmHg
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what med is contraindicated in pts with glaucoma
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scopalamine
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