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57 Cards in this Set
- Front
- Back
S/S of tension pneumothorax:
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Hypotension
Hypoxemia Tachycardia ↑ CVP ↑ PIP Absence of unilateral breath sounds Tracheal shift Asymmetric chest wall movement |
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Differences in Neonatal Respiratory System:
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↓ Lung compliance
↑ Chest wall compliance ↓ FRC ≈ 30 ml/kg |
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Complications of Transtracheal Jet Ventilation:
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1. Barotrauma & pneumothorax
2. Sub Q emphysema 3. Mediastinal air (emphysema) 4. Exhalation difficulty 5. Arterial perforation 6. Esophageal puncture 7. Damage to tracheal mucosa |
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Cranial nerves
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oh oh oh, to touch and feel vaginas gives Vic a hard-on
oh: Olfactory oh: Optic oh: oculomotor to: trochlear touch: trigminal and: abducens vaginas: vestibulocochlear gives: glossopharyngeal Vic: vagus A: (Accessory) Hard-on: Hypoglossal |
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I Olfactory
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Smell
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II Optic
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Vision
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III Occulomotor
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Adduction of eye (medial re), pupil size
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IV Trochlear
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Eye movements
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V Trigeminal
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Chewing, mastication, Facial sensory
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VI Abducens
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Abduction of eye (lateral rectus)
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VII Facial
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Facial muscles, taste (anterior 1/3 tongu
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VIII Acoustic
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Balance (vestibular), hearing (cochlear)
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IX Glossopharyngeal
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Taste (posterior 1/3), carotid & sinus af
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X Vagus
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Parasympathetic efferents, ↓ HR
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XI Spinal Accessory
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Motor control of larynx & pharynx
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XII Hypoglossal
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Tongue muscles
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Intracranial Transmural Pressure =
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MAP-ICP
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ICP:
Normal = |
5-15 mm Hg
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IC Volume:
-Brain matter & intracellular -H2O -Blood -CSF |
Brain matter & Intracellular H2O = 80%
Blood 12% CSF = 8% |
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Cranial Fossae:
Anterior = Middle = Posterior = |
Anterior = Frontal lobe
Middle = Temporal lobe Posterior = Brainstem & cerebellum |
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Twelve S/S of ↑ ICP:
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1. Headache
2. N & V 3. Blurred vision 4. Unilateral pupil dilation 5. Papilledema 6. Cranial nerve III (oculomotor) paralysis, ∅ adduct 7. Cranial nerve VI (abducens) paralysis, ∅ abduct 8. HTN 9. Bradycardia 10. Irregular respirations 11. Altered LOC 12. Seizures |
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Cushing's Triad
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HTN, Bradycardia, Irregular respirations
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Treatment of ↑ ICP:
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1. Dehydrate the brain with Mannitol or Lasix
2. Give steroids 3. Hyperventilate to PaCO2 25-30 mm Hg (1/2 life 6 hours) 4. Restrict fluids 5. Elevate HOB to 300 6. Administer cerebral vasoconstrictor (pentathol, etomidate) 7. Control BP 8. Cool pt to 340 C for cerebral protection |
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Specific gravity of CSF =
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1.003-1.009
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CSF forms @ __ ml/hr or _____ml/day in the choroid plexus of brain
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21 ml/hr
500 ml/day |
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Where is the Choroid plexus located?
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Choroid plexus is located specifically in temporal horn of each lateral ventricle, the posterior portion of the third ventricle, and the roof of the fourth ventricle.
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CSF is reabsorbed mostly in the
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CSF is reabsorbed mostly in the arachnoid villi (4/5), but also in spinal villi & lymphatics.
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Total volume of CSF
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Total volume of CSF = 150 ml
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the most common site of CSF obstruction
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Aqueduct of Sylvius
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Four factors governing passage across BBB:
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Size
Charge Lipid solubility Degree of protein binding The Chemoreceptor trigger zone (CRTZ) and the area surrounding the posterior pituitary have no BBB. |
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Four electrolyte disorders that ↓ Seizure threshold:
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1. Hypocalcemia
2. Hypomagnesemia 3. Hyponatremia 4. Hypernatremia Demerol is the opiod most likely to cause seizures |
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Acute Spinal Shock:
Hypotension occurs due to? bradycardia due to? |
Hypotension occurs due to sympathetic blockade
bradycardia due to blockade of cardiac accelerators. |
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Triple H Therapy:
For treatment of |
For treatment of cerebral vasospasm
-Hypervolemia = CVP > 10 mm Hg, PCWP = 12-20 -Hypertension = SBP 160-200 mm Hg -Hemodilution = Hct 33% |
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Occulocardiac Reflex:
Afferent pathway = Efferent pathway = |
Afferent pathway = Trigeminal nerve
Efferent pathway = Vagus nerve |
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Wake-up test monitors the?
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monitors the anterior (ventral) spinal cord, which is supplied by the anterior spinal arteries. These are motor tracts.
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Complications of wake-up test:
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1. Recall
2. Extubation 3. Dislodgement of spinal instrumentation 4. VAE from spontaneous ventilation |
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Estimated Blood Volume:
Premie = Infant = Toddler = Child = Men = Women= |
Premie = 90 ml/kg
Infant = 80 Toddler = 75 Child = 72 Men = 70 Women = 65 |
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Total Body Water (TBW)
Adult = Neonate = Premie = |
Adult = 60%
Neonate = 80% Premie = 90% |
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CPP =
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MAP-ICP or MAP-RAP
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In Parkinson’s avoid:
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Reglan
Compazine Droperidol |
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Hyperventilation
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↓ K+
↓ Ca++ |
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Describe the flow of CSF:
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Choroid Plexus - Lateral Ventricle - Foramen Monroe - 3rd Ventricle - Aqueduct of Sylvius - 4th Ventricle - Foramen luschka and Foramen Magendie - subarachnoid space - Brain - Arachnoid Villi
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What blood vessels make up the Circle of Willis?
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R/L Internal Carotid
Basilar & Vertebral Arteries |
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Spinal Cord:
Sensory = Motor = Preganglionic SNS |
Sensory – Afferent – Dorsal Horn ‘sad’
Motor – Efferent – Ventral Horn ‘motor VehiclE’ Preganglionic SNS – Intermediolateral Horn |
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Dorsal-Lemniscal (Sensory):
SSEP Monitoring? |
(posterior spinal arteries)•
Touch, pressure, vibration= propioception •Dorsal (posterior) cord – Cuneatus & Gracilis tracts •Ascend ipsilateral side •Decussate @ brainstem to contralateral thalamus & sensory cortex/ direct route •Also goes to RAS where it percolates to sensory cortex Reticular activating system/ indirect route |
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Ascending Pain (Anterolateral):
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Lateral Spinothalamic Tract
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Ascending Pain (Anterolateral):
A-δ Fibers – |
Myelinated, Fast “first” Pain & temp
Rexed’s lamina I & V, dorsal horn Neurotransmitter - glutamate |
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Ascending Pain (Anterolateral):
C Fibers – |
Unmyelinated, Slow “dull” Pain & temp
Rexed’s lamina II (substantia gelatinosa) & III, dors Neurotransmitter – substance P Interneurons go from II & III to V |
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Ascending Pain (Anterolateral):
Both fibers ascend or descend in the tract of Lissauer 1-3 segmnt Both fibers decussate and ascend on the contralateral side. |
..
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Descending Pain (Dorsolateral):
Dorsolateral Funiculus – |
modulates pain
(spinal analgesia) Originate in the periventricular and periaqueductal gray areas and terminate on enkephalin-releasing interneurons in Rexed’s lamina II (substantia gelatinosa). This inhibits the release of substance P. (Presynaptic inhibition) |
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Pain categories:
Nociceptive: Neuropathic: |
Nociceptive: (physiologic, carried by A-delta & C fibers)
Somatic-sharp & well localized Visceral-diffuse, dull & vague Neuropathic: Caused by abnormal processing of painful stimuli. Neuropathic pain may occur after injury to neural tissue secondary to systemic disease, infection, trauma, ischemia, deficiencies in metabolism or nutrition, or exposure to environmental toxins or neurotoxin medications. |
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Five factors that alter the latency and/or amplitude of SSEP:
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1. ↓ Cerebral perfusion 20 hypotension, ↓ PaCO2, ↑ ICP
2. Cerebral hypoxia 3. Hypothermia 4. Hyperthermia 5. Hemodilution; Hct < 15% |
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Preganglionic Parasympathetic Nerves originate:
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Cranial nerves III, VII, IX, & X
Sacral segments S2-S4 Myocyte = muscle cell |
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Weak Acids:
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Weak Acids: (Thiopental, other barbit, [+ Charge/ Na+, Mg++],
Proton Donor Acid + Acid = unionized |
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Weak Base:
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Weak Base: (LA, ketamine, opiods, benzos) [- Charge/ Cl-, SO4-]
Proton Acceptor Base + Base = unionized |
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Local Anesthesia:
Potency = Duration = Speed of Onset= |
Potency = lipid solubility
Duration = protein binding & solubility Speed of Onset = pKa |
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What is the "Order" in which local anesthetics block the different nerves
"Tammy is carrying pickled eggs, beer, summer sausage" |
Tammy = Tracheal
Is = Intercostal Carrying = Caudal Pickled = Paracervical Eggs= Epidural Beer = Brachial Plexus Summer = Spinal Sausage = Subcutaneous |