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57 Cards in this Set

  • Front
  • Back
S/S of tension pneumothorax:
Hypotension
Hypoxemia
Tachycardia
↑ CVP
↑ PIP
Absence of unilateral breath sounds
Tracheal shift
Asymmetric chest wall movement
Differences in Neonatal Respiratory System:
↓ Lung compliance
↑ Chest wall compliance
↓ FRC ≈ 30 ml/kg
Complications of Transtracheal Jet Ventilation:
1. Barotrauma & pneumothorax

2. Sub Q emphysema

3. Mediastinal air (emphysema)

4. Exhalation difficulty

5. Arterial perforation

6. Esophageal puncture

7. Damage to tracheal mucosa
Cranial nerves
oh oh oh, to touch and feel vaginas gives Vic a hard-on

oh: Olfactory
oh: Optic
oh: oculomotor
to: trochlear
touch: trigminal
and: abducens
vaginas: vestibulocochlear
gives: glossopharyngeal
Vic: vagus
A: (Accessory)
Hard-on: Hypoglossal
I Olfactory
Smell
II Optic
Vision
III Occulomotor
Adduction of eye (medial re), pupil size
IV Trochlear
Eye movements
V Trigeminal
Chewing, mastication, Facial sensory
VI Abducens
Abduction of eye (lateral rectus)
VII Facial
Facial muscles, taste (anterior 1/3 tongu
VIII Acoustic
Balance (vestibular), hearing (cochlear)
IX Glossopharyngeal
Taste (posterior 1/3), carotid & sinus af
X Vagus
Parasympathetic efferents, ↓ HR
XI Spinal Accessory
Motor control of larynx & pharynx
XII Hypoglossal
Tongue muscles
Intracranial Transmural Pressure =
MAP-ICP
ICP:
Normal =
5-15 mm Hg
IC Volume:

-Brain matter & intracellular
-H2O
-Blood
-CSF
Brain matter & Intracellular H2O = 80%

Blood 12%

CSF = 8%
Cranial Fossae:

Anterior =
Middle =
Posterior =
Anterior = Frontal lobe
Middle = Temporal lobe
Posterior = Brainstem & cerebellum
Twelve S/S of ↑ ICP:
1. Headache
2. N & V
3. Blurred vision
4. Unilateral pupil dilation
5. Papilledema
6. Cranial nerve III (oculomotor) paralysis, ∅ adduct
7. Cranial nerve VI (abducens) paralysis, ∅ abduct
8. HTN
9. Bradycardia
10. Irregular respirations
11. Altered LOC
12. Seizures
Cushing's Triad
HTN, Bradycardia, Irregular respirations
Treatment of ↑ ICP:
1. Dehydrate the brain with Mannitol or Lasix
2. Give steroids
3. Hyperventilate to PaCO2 25-30 mm Hg (1/2 life 6 hours)
4. Restrict fluids
5. Elevate HOB to 300
6. Administer cerebral vasoconstrictor (pentathol, etomidate)
7. Control BP
8. Cool pt to 340 C for cerebral protection
Specific gravity of CSF =
1.003-1.009
CSF forms @ __ ml/hr or _____ml/day in the choroid plexus of brain
21 ml/hr

500 ml/day
Where is the Choroid plexus located?
Choroid plexus is located specifically in temporal horn of each lateral ventricle, the posterior portion of the third ventricle, and the roof of the fourth ventricle.
CSF is reabsorbed mostly in the
CSF is reabsorbed mostly in the arachnoid villi (4/5), but also in spinal villi & lymphatics.
Total volume of CSF
Total volume of CSF = 150 ml
the most common site of CSF obstruction
Aqueduct of Sylvius
Four factors governing passage across BBB:
Size
Charge
Lipid solubility
Degree of protein binding
The Chemoreceptor trigger zone (CRTZ) and the area surrounding the posterior pituitary have no BBB.
Four electrolyte disorders that ↓ Seizure threshold:
1. Hypocalcemia
2. Hypomagnesemia
3. Hyponatremia
4. Hypernatremia
Demerol is the opiod most likely to cause seizures
Acute Spinal Shock:

Hypotension occurs due to?

bradycardia due to?
Hypotension occurs due to sympathetic blockade

bradycardia due to blockade of cardiac accelerators.
Triple H Therapy:

For treatment of
For treatment of cerebral vasospasm
-Hypervolemia = CVP > 10 mm Hg, PCWP = 12-20
-Hypertension = SBP 160-200 mm Hg
-Hemodilution = Hct 33%
Occulocardiac Reflex:


Afferent pathway =

Efferent pathway =
Afferent pathway = Trigeminal nerve

Efferent pathway = Vagus nerve
Wake-up test monitors the?
monitors the anterior (ventral) spinal cord, which is supplied by the anterior spinal arteries. These are motor tracts.
Complications of wake-up test:
1. Recall
2. Extubation
3. Dislodgement of spinal instrumentation
4. VAE from spontaneous ventilation
Estimated Blood Volume:

Premie =

Infant =

Toddler =

Child =

Men =

Women=
Premie = 90 ml/kg
Infant = 80
Toddler = 75
Child = 72
Men = 70
Women = 65
Total Body Water (TBW)

Adult =

Neonate =

Premie =
Adult = 60%

Neonate = 80%

Premie = 90%
CPP =
MAP-ICP or MAP-RAP
In Parkinson’s avoid:
Reglan

Compazine

Droperidol
Hyperventilation
↓ K+
↓ Ca++
Describe the flow of CSF:
Choroid Plexus - Lateral Ventricle - Foramen Monroe - 3rd Ventricle - Aqueduct of Sylvius - 4th Ventricle - Foramen luschka and Foramen Magendie - subarachnoid space - Brain - Arachnoid Villi
What blood vessels make up the Circle of Willis?
R/L Internal Carotid

Basilar & Vertebral Arteries
Spinal Cord:

Sensory =

Motor =

Preganglionic SNS
Sensory – Afferent – Dorsal Horn ‘sad’

Motor – Efferent – Ventral Horn ‘motor VehiclE’

Preganglionic SNS – Intermediolateral Horn
Dorsal-Lemniscal (Sensory):

SSEP Monitoring?
(posterior spinal arteries)•

Touch, pressure, vibration= propioception

•Dorsal (posterior) cord – Cuneatus & Gracilis tracts

•Ascend ipsilateral side

•Decussate @ brainstem to contralateral thalamus & sensory cortex/ direct route

•Also goes to RAS where it percolates to sensory cortex
Reticular activating system/ indirect route
Ascending Pain (Anterolateral):
Lateral Spinothalamic Tract
Ascending Pain (Anterolateral):

A-δ Fibers –
Myelinated, Fast “first” Pain & temp

Rexed’s lamina I & V, dorsal horn

Neurotransmitter - glutamate
Ascending Pain (Anterolateral):

C Fibers –
Unmyelinated, Slow “dull” Pain & temp

Rexed’s lamina II (substantia gelatinosa) & III, dors

Neurotransmitter – substance P

Interneurons go from II & III to V
Ascending Pain (Anterolateral):


Both fibers ascend or descend in the tract of Lissauer 1-3 segmnt

Both fibers decussate and ascend on the contralateral side.
..
Descending Pain (Dorsolateral):

Dorsolateral Funiculus –
modulates pain

(spinal analgesia)

Originate in the periventricular and periaqueductal gray areas and terminate on enkephalin-releasing interneurons in Rexed’s lamina II (substantia gelatinosa). This inhibits the release of substance P. (Presynaptic inhibition)
Pain categories:

Nociceptive:

Neuropathic:
Nociceptive: (physiologic, carried by A-delta & C fibers)

Somatic-sharp & well localized
Visceral-diffuse, dull & vague

Neuropathic:
Caused by abnormal processing of painful stimuli. Neuropathic pain may occur after injury to neural tissue secondary to systemic disease, infection, trauma, ischemia, deficiencies in metabolism or nutrition, or exposure to environmental toxins or neurotoxin medications.
Five factors that alter the latency and/or amplitude of SSEP:
1. ↓ Cerebral perfusion 20 hypotension, ↓ PaCO2, ↑ ICP
2. Cerebral hypoxia
3. Hypothermia
4. Hyperthermia
5. Hemodilution; Hct < 15%
Preganglionic Parasympathetic Nerves originate:
Cranial nerves III, VII, IX, & X
Sacral segments S2-S4

Myocyte = muscle cell
Weak Acids:
Weak Acids: (Thiopental, other barbit, [+ Charge/ Na+, Mg++],

Proton Donor

Acid + Acid = unionized
Weak Base:
Weak Base: (LA, ketamine, opiods, benzos) [- Charge/ Cl-, SO4-]

Proton Acceptor

Base + Base = unionized
Local Anesthesia:

Potency =

Duration =

Speed of Onset=
Potency = lipid solubility

Duration = protein binding
& solubility

Speed of Onset = pKa
What is the "Order" in which local anesthetics block the different nerves

"Tammy is carrying pickled eggs, beer, summer sausage"
Tammy = Tracheal
Is = Intercostal
Carrying = Caudal
Pickled = Paracervical
Eggs= Epidural
Beer = Brachial Plexus
Summer = Spinal
Sausage = Subcutaneous