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6 Cards in this Set

  • Front
  • Back
What is the suggested workup for dementia?
-diagnostic interview (from pt. and another reliable source)
-office based clinical assessment: physical exam, MMSE, neurological exam, lab evaluation, imaging studies, EEG
-neuropsychologic testing is diagnosis is unclear
What is the cause of Alzheimers? What is the onset? The risk of getting AD is increased with what? When is the definitive diagnosis made at?
-dont know the cause!
-risk is increased with individuals who carry the ApoE4 allelle
-definitive diagnosis is made at autopsy!
Development of cognitive defects in AD is manifested by what?
-memory impairment along with: aphasia, apraxia, agnosia, disturbance in executive functioning (reasoning). Also see social or occupational impairment
What are the expectations of AD medications?
-improve, maintain or slow the decline
-control troublesome behavior
-ease loss of independence
-help caregiver
-delay placement in a home
What should be the role of the caregiver for all 3 stages of the disease? mild moderate and advanced
-mild: mostly supportive, reassurance, monitor activities, insure affairs are in order (ex. will), allow as much independence as possible.
-moderate: driving resticted, closer supervision, caregiver should take over financial affairs, monitor hygiene and nutrition, inform physician of concerning behaviors
-Advanced: may need to put in a home, 24 hour surveillance, will have to assis in ALL activities of daily living
How would a pt. present with amyotrophic lateral sclerosis? (aka lou gherigs disease) What will be most important for evaluation?
-the defective gene codes for superoxide dismutase. We dont know what causes this though.
-you see both upper and lower motor neuron abnormalities. Upper: atrophy, fasiculations and weakness. Lower: spasticity, hyperactive reflexes
-pt. may present with difficulty swallowing or speaking. Rarely affects ocular muscles, sphincters. Sensation and cognigiton ARE NOT affected
-get an MRI of the cervical spine to look for STENOSIS. For electrodiagnostic studies, nerve conduction will be normal, electromyography will show evidence of diffuse dennervation
-side note: for ALS treatment you have to get social services involved