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62 Cards in this Set
- Front
- Back
Central Nervous system (CNS) |
contains the brain and spinal cord |
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Peripheral nervous system (PNS) |
consists of nerves that carry both sensory and motor information to and from CNS |
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Sensory Afferent |
A division of the PNS, that carries information towards the CNS |
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Motor Efferent |
A division of the PNS that carries information from CNS to bring about or cause a response |
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In the 3 box model of the nervous system, what branch of the nervous system is involved with "sensory" |
PNS, specifically with sensory afferent |
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In the 3 box model of the nervous system, what branch of the nervous system is involved with "Integration" |
CNS |
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In the 3 box model of the nervous system, what branch of the nervous system is involved with "data out" or "motor movement" |
PNS, specifically the motor efferent |
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What is sensory transduction |
The process of sensory receptors converting an energy type into ion movement across membranes |
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What are the three energy types? |
1. Electromagnetic = light/vision. 2. Mechanical = touch or hearing. 3. Chemical = taste or smell |
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What is the neuron doctrine |
states that neurons are the fundamental structure and function of the nervous system |
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What are the five tastes? |
1. Salty 2. Sweet. 3. Umami. 4. Sour. 5. Bitter |
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What is flavor |
the combination of taste and smell |
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Cellularists |
the group of people who believe that neurons are individual cells |
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Reticularists |
People who believe that every neuron is connected to each other |
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Fast axo plasmic transport |
move 200 - 400 mm day, proteins are made on rough er |
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slow axo plasmic transport |
.5 - 2mm/day, proteins made on free ribosomes |
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Law of dynamic polarization |
unidirectional flow of information in the nervous system from the dendrite -> Cell body -> Axon -> Axon terminals |
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Input region |
Contains the dendrites and cell body, receives input from other cells, has clusters of ligand-gated channels called neurotransmitter operated channels |
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Conductile region |
conducting signals from input region to output region, includes the axon, characterized by ion channels opened by charge/voltage |
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output region |
includes the axon terminals which contains the vesicles that contain neurotransmitters, it coverts electrical signals to chemical signals |
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When they say the neuron is asymmetrical that means |
there is one way transmission and there are three distinct parts - input, conductile, and output |
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Retinal ganglion cells |
Neurons whose cell bodies are located in the retina and whose output regions are in the brain known as the thalamus |
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oligodencroytes
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responsible for forming the myelin sheaths axons in the CNS.
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microglialcells
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cells that are modified microphages in the CNS
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Schwanncells
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myelin producing cells in the peripheral nervous system that envelope only a single axon, and clean up debris after peripheral nerve damage and support regenerationof peripheral nerves |
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astrocytes
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regulate the concentration of ions, particularly potassium, and it regulates the concentration of neurotransmitters in the extracellular space |
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in a resting neuron, what is the ion concentration outside the cell and inside the cell |
Na+ is high outside the cell and low inside, K+ is high inside but low outside |
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the membrane potential seeks |
equilibrium potential of the ion whose permeability is dominant |
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Voltage-gated Na+ Channels
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Depolarize the membrane potential and charge sensitive
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Voltage-gated K+ Channels
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Repolarize the membrane potential and charge sensitive
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Depolarization
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A change within the membrane potential in which it becomes more positive
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repolarization
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a change within the membrane potential in which is becomes more negative
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What are the three neurotransmitter fates? |
1) bind to receptor, 2) reuptake into glia 3)enzymatic degradation |
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Synapto Tagmin |
Protein that binds to calcium |
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Synapse |
a site where one neuron communicates to another neuron |
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The more K+ channels affects the membrane resistance how? |
It decreases membrane resistance which decreases the likelihood that a action potential will be generated |
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What are the two main inhibitory neurons |
GABA (CNS) Glycine (PNS) |
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Temporal Summation |
potentialsarrive within a narrow enough time window when the potentials can add together
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Spatial Summation |
whenpotentials originating in different regions of the dendritic tree or cell bodysummate (if sufficient depolarizingpotentials from different areas of the cell body or dendrite arrive at thetrigger zone and summate, the membrane in the axon may reach threshold and firean action potential
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The influx of Cl- into the cell does what |
hyperpolarizes the cell (decreases the likelihood of an action potential) |
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Trigger zone |
clustersof voltage gated NA channels on the axon near cell body, responsible for actionpotential
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White matter |
Conductile regions of the neuron in the CNS |
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gray matter |
Cell bodies/input region of the neuron |
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Ganglion |
Collection of cell bodies in the PNS |
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Horns are in what? |
CNS |
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Roots are in what? |
PNS |
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anything above the dorsal midline is what |
Mostly sensory neurons |
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Anything below the midline, in the ventral area is what |
Mostly motor neurons |
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What is contained in the ventral horn |
The cell bodies of motor neurons |
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What is contained in the dorsal ganglia |
the cell bodies of primary afferent neurons |
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Motor neurons release what kind of signal |
EPSP |
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Sensory neurons release what kind of signal |
Generator potential |
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Ventral Root |
The place where the axons of motor neurons exit |
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Dorsal Columns |
tracts that carry information about light touch and propricoception from the periphery towards the brain |
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The DCML pathway carries information about what? |
Fine touch, proprioception, and vibration |
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Spinothalamic pathway/Anterolateral pathway |
Pain, temperature, crude touch (pressure) |
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When is there cross over the midline in the DCML pathway? |
Dorsal column nuclei |
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When is there cross over the midline in the spinothalamic pathway? |
At the level it enters the spinal cord |
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When is there cross over in the lateral corticospinal pathway |
in the desccuation of the pyramids |
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Where is the motor cortex located |
Precentral Gyrus |
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Where is the somatosensory cortex located |
Post central gryus |
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Motor unit |
The lower motor neuron and the muscles it intervates |