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19 Cards in this Set

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UTI dx
leukocyte esterase
nitrites
urine sediment w/ wbcs & bacteria
Accounts for 70% UTIs:
Name the alkaline bugs: (PHKU)
Expect which bug MC in alkaline urine ?
Name some more UTI bugs: KEGS
E. Coli
Proteus, HI, Klebsiella and Ureaplasma are all alkaline.
Proteus
Kleb, Enterococcus, GBS, Staph (coagulase negative)
E. Coli ABX
amoxicillin
Macrodantin
Bactrim (TMP-SMX)
MC UTI complication.
pyelonephritis (asc k. infection)
Bacterial Vaginosis organisms
Treatment ?
Gardnerella vaginalis
Bacteroides
Mycoplasma hominis
Treatment: Met
GBS sepsis mortality rate
Tell me about GBS:
25-50%
GBS: G+, cocci, catalase(-), complete hemolysis (B), ex. S. agalactiae, bacitracin resistant, give Pen at 30 wks, Amp alternatively.
MC precursor of neonatal sepsis
chorioamnionitis
Chorioamnionitis dx ?
culture amniotic fluid
Most sensitive test for chorioamnionitis ?
- which cells secrete this ?
- what does it stimulate ?
IL-6 amniotic fluid levels
- Th cells and macrophages
- acute phase reactants (which are serum proteins) and IGs.
HSV complications
herpes encephalitis leading to neuro devastation and death
pneumonia
viral sepsis
Prevent xmission of VZV:
What is the VZV structure ?
CMV ds & cure ?
Only viruses that acquiring envs by nuc membrane budding ?
VZ immune globulin.
Same structure as CMV (CHDED). Herpes, ENV, DS-L
Chicken pox, zoster, shingles, live attenuated virus at 12-15 months.
Herpes
Parvo B19 complications
hemolytic anemia
hydrops - edema & swelling
death
CMV stats
Tell me about CMV: (CHDED)
incidence 1% of newborns
< 10% with complications
CMV: Herpes, DNA, ENV, DS-L
- infection in immunsuppressed, congenital effects
- proph w/ Ganciclovir at CD4 < 50
- but recall the neonate on NEJM with purpura and thrombocytopenia that didn't survive
Is CRS transmitted across the placenta ?
Who is RESLIT ?
No. Thus IgM titers in the infant are indicative of infection.
RESLIT is the little German Rubella Toga virus riding a mosquito.
(RNA, Env, SS+L, Toga) see him sitting behind the ear and then trying to use an IgM hammer to cross the plancenta to the fetus (he can't, of course).
CRS: RNA, Env, SS+L, Icos, Togavirus (German measles)
- post-auricular tenderness
- live, attenuated vaccine
- Toga is also Eastern &amp;amp;amp; Western equine
- all Togaviruses are arboviruses (mosquito, tick, sandfly)
Transmission rate to fetus in untreated HIV.
25%
Given if mom is + HBsAg
Tell me about HepB:
HepB immunoglobulin
Hepadenavirus (hexagonal), Env, DS-partially circular
acute or chronic hepatitis
not a retrovirus but has rev. transcriptase
Say "Treponema pallidum transmission is:"
transplacental
Toxoplasmosis ID
IgM in the neonate
How would RESLIT arrive at the placental blood barrier with his ineffectual IgM hammer ?
Maternal arterial blood would cross the decidua basalis to bathe the syncytiotrophoblast / cytotrophoblast. But the CRS IgM hammer would not break the synctiotrophoblast to reach the fetal / artery vein combination.