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19 Cards in this Set
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- 3rd side (hint)
UTI dx
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leukocyte esterase
nitrites urine sediment w/ wbcs & bacteria |
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Accounts for 70% UTIs:
Name the alkaline bugs: (PHKU) Expect which bug MC in alkaline urine ? Name some more UTI bugs: KEGS |
E. Coli
Proteus, HI, Klebsiella and Ureaplasma are all alkaline. Proteus Kleb, Enterococcus, GBS, Staph (coagulase negative) |
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E. Coli ABX
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amoxicillin
Macrodantin Bactrim (TMP-SMX) |
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MC UTI complication.
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pyelonephritis (asc k. infection)
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Bacterial Vaginosis organisms
Treatment ? |
Gardnerella vaginalis
Bacteroides Mycoplasma hominis Treatment: Met |
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GBS sepsis mortality rate
Tell me about GBS: |
25-50%
GBS: G+, cocci, catalase(-), complete hemolysis (B), ex. S. agalactiae, bacitracin resistant, give Pen at 30 wks, Amp alternatively. |
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MC precursor of neonatal sepsis
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chorioamnionitis
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Chorioamnionitis dx ?
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culture amniotic fluid
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Most sensitive test for chorioamnionitis ?
- which cells secrete this ? - what does it stimulate ? |
IL-6 amniotic fluid levels
- Th cells and macrophages - acute phase reactants (which are serum proteins) and IGs. |
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HSV complications
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herpes encephalitis leading to neuro devastation and death
pneumonia viral sepsis |
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Prevent xmission of VZV:
What is the VZV structure ? CMV ds & cure ? Only viruses that acquiring envs by nuc membrane budding ? |
VZ immune globulin.
Same structure as CMV (CHDED). Herpes, ENV, DS-L Chicken pox, zoster, shingles, live attenuated virus at 12-15 months. Herpes |
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Parvo B19 complications
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hemolytic anemia
hydrops - edema & swelling death |
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CMV stats
Tell me about CMV: (CHDED) |
incidence 1% of newborns
< 10% with complications CMV: Herpes, DNA, ENV, DS-L - infection in immunsuppressed, congenital effects - proph w/ Ganciclovir at CD4 < 50 - but recall the neonate on NEJM with purpura and thrombocytopenia that didn't survive |
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Is CRS transmitted across the placenta ?
Who is RESLIT ? |
No. Thus IgM titers in the infant are indicative of infection.
RESLIT is the little German Rubella Toga virus riding a mosquito. (RNA, Env, SS+L, Toga) see him sitting behind the ear and then trying to use an IgM hammer to cross the plancenta to the fetus (he can't, of course). |
CRS: RNA, Env, SS+L, Icos, Togavirus (German measles)
- post-auricular tenderness - live, attenuated vaccine - Toga is also Eastern &amp;amp; Western equine - all Togaviruses are arboviruses (mosquito, tick, sandfly) |
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Transmission rate to fetus in untreated HIV.
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25%
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Given if mom is + HBsAg
Tell me about HepB: |
HepB immunoglobulin
Hepadenavirus (hexagonal), Env, DS-partially circular acute or chronic hepatitis not a retrovirus but has rev. transcriptase |
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Say "Treponema pallidum transmission is:"
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transplacental
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Toxoplasmosis ID
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IgM in the neonate
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How would RESLIT arrive at the placental blood barrier with his ineffectual IgM hammer ?
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Maternal arterial blood would cross the decidua basalis to bathe the syncytiotrophoblast / cytotrophoblast. But the CRS IgM hammer would not break the synctiotrophoblast to reach the fetal / artery vein combination.
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