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57 Cards in this Set

  • Front
  • Back
T/F: large animals are commonly transfused.
False
T/F: in cattle single unmatched whole blood transfusions are generally safe and well tolerated.
True
should you cross-match blood if you are planning to transfuse a cow multiple times?
yes
T/F: blood typing does not detect antibodies between the patient and the potential donor.
True
T/F: blood typing detects antibodies between the patient and the potential donor.
False -- cross-matching identifies antibodies between the patient and the potential donor
T/F: cross-matching identifies antibodies between the patient and the potential donor
true
when viewing a canine DEA 1.1 blood-typing card, agglutination indicates what?
agglutination is a (+) test result

.: the blood you were testing is also 1.1 (+)
when viewing a canine DEA 1.1 blood-typing card, no agglutination indicates what?
that the blood you are testing is DEA 1.1 (-)
in canine blood-typing gels, what does a (-) test result look like?
the tube with blood sediment on the bottom is negative
which canine blood type is the universal recipient?
DEA 1.1 (+)
T/F: Mik is non-AB blood group antigen that is common in most DSH cats
True
T/F: Dal is a common blood antigen found in most dogs
True
CLICKER:

Blood type testing indicates that the donor is DEA 1.1 (+) and the recipient is DEA 1.1 (-). Best practices indicate:

A. go ahead and transfuse, no reaction is expected
B. do not transfuse, the recipient will become sensitized to the DEA 1.1
C. perform a crossmatch, you don't know their history.
B
CLICKER:
If you transfuse a Type B cat with Type A blood you can expect:

A. mild reaction, Type B cats have weak alloantibodies against type A blood
B. No reaction, it is only AB into B that causes problems
C. No reaction, it is only AB into A that causes problems
D. Severe hemolytic disease, Type B cats have major alloantibodies against Type A blood
D ---- British hate Americans
Blood typing and transfusions are both uncommon and impractical in all large animals except:

goat
sheep
cow
horse
llama
horse
T/F: in large animals single-uncrossmatched whole blood transfusions tend to be well-tolerated
True
what are the 2 very immunogenic blood types of horses?
Aa and Qa
T/F: anti-Aa antibodies and anti-Qa antibodies can lead to neonatal isoerythrolysis
True
T/F: there is no universal blood donor in horses.
True
T/F: there is a universal blood donor in horses.
false --- NO universal blood donor in horses
does neonatal isoerythrolysis affect the first or second foal?
second
what are the clinical signs noted in foals with neonatal isoerythrolysis?
lethargy, weakness, icterus
increased HR and RR
severe hemoglobinemia and hemoglobinuria
severe hypoxia leading convulsions, coma, and death
In the Jaundiced foal agglutination test, you mix what 2 things to see if there is agglutination?
colostrum from mare + RBCs from foal
who is the BEST immediate blood donor for a foal with neonatal isoerythrolysis?
the mare
who is the WORST immediate blood donor for a foal with neonatal isoerythrolysis?
the sire
Which canine blood type is the universal recipient?
DEA 1.1 (+)
Which canine blood type is the universal donor?
DEA 4 only
Which canine blood type is the ideal donor?
DEA 1.1 (-)
Major crossmatch =
Patients serum mixed with donor RBCs
Minor crossmatch =
donor's serum mixed with patient RBCs
When are cats crossmatched?
before the first blood transfusion
when are dogs and horses crossmatched?
before the second transfusion
what does it mean to have a negative crossmatch?
recipient is NOT likely at risk for a transfusion reaction from the donor RBCs
what does it mean to have a positive crossmatch?
recipient IS at risk for a transfusion reaction. SHOULD NOT BE TRANSFUSED WITH THIS DONOR
CLICKER:
Dogs should be blood-typed:

A. prior to first transfusion
B. prior to second transfusion
C. only if they are DEA 1.1 or 1.2
D. only if the are DEA 4
A
CLICKER:
Dogs should be crossmatched:

A. prior to first transfusion
B. prior to second transfusion
C. only if they are DEA 1.1 or 1.2
D. only if the are DEA 4
B
CLICKER:

Blood type testing indicates that 2 dogs of unknown transfusion history are DEA 1.1negative. What do best practices dictate?

A. go ahead and transfuse, no reaction expected
B. mild reaction if one is DAL negative
C. do a crossmatch, you don't know their history
D. go ahead and transfuse, you have extra blood products on hand.
C
Donor selection:

blood donor dogs should be...
DEA 1.1 or 1.2 NEGATIVE
Donor selection:

blood donor cats should be...
type A (most common)
type B
Donor selection:

blood donor horses should be...
young gelding
female: never transfused and never pregnant

lack Aa and Qa antigens
if the animal is thrombocytopenic which type of transfusion should you use?

Whole blood/RBCs
Plasma
Platelet-Rich Plasma
Platelet-Rich plasma
if the animal has Fe Deficiency Anemia which type of transfusion should you use?

Whole blood/RBCs
Plasma
Platelet-Rich Plasma
Whole blood/RBCs
if the animal is hypoproteinemic which type of transfusion should you use?

Whole blood/RBCs
Plasma
Platelet-Rich Plasma
plasma
if the animal has clotting factor deficiencies which type of transfusion should you use?

Whole blood/RBCs
Plasma
Platelet-Rich Plasma
plasma
what are the 4 types of transfusion reactions that can happen?
1. immune-mediated
2. acute or delayed hemolysis
3. febrile and allergic
4. non-immune-mediated (sepsis and transmission of infectious agents)
what type of transfusion reaction is expected if a Type B cat is given Type A or Type AB blood?
immune-mediated and acute reaction will occur

acute indicates intravascular hemolysis
T/F: acute transfusion reaction are uncommon in dogs and horses.
true
T/F: acute transfusion reaction are common in dogs and horses.
FALSE -- UNCOMMON
what are some clinical signs that the P is having an acute hemolytic transfusion reaction?
tachycardia
dyspnea
hypotension
salivation
tremors
vomiting
pyrexia
delayed transfusion reaction indicates that we have ________ hemolysis occuring (intravascular/extravascular)
EXTRAVASCULAR
60-90% of transfusion reactions are which type?
febrile and allergic
Febrile and allergic transfusion reactions are commonly seen with which type of transfusion?

whole blood
plasma
plasma
CLICKER:

the major crossmatch is ________ to __________.

a. patient serum to donor RBCs
b. donor serum to patients RBCs
c. donor serum to donor RBCs
d. patient serum to patient RBCs
A
CLICKER:

the minor crossmatch is ________ to __________.

a. patient to donor RBCs
b. donor serum to patients RBCs
c. donor serum to donor RBCs
d. patient serum to patient RBCs
B
CLICKER:

cats should be typed and crossmatched prior to:

a. prior to first transfusion
b. prior to second transfusion
c. only if type B
d. only if type A
e. only if type AB
A
CLICKER:
the crossmatch gel tube shows agglutination:

a. this is a negative reaction; do not transfuse with this donor's RBCs
b. this is a positive reaction; ok to transfuse with donor blood
c. this is a negative reaction; ok to transfuse with donor blood
d. this is a positive reaction; do not transfuse with donor blood
D
CLICKER:
the crossmatch gel tube shows NO agglutination:

a. this is a negative reaction; do not transfuse with this donor's RBCs
b. this is a positive reaction; ok to transfuse with donor blood
c. this is a negative reaction; ok to transfuse with donor blood
d. this is a positive reaction; do not transfuse with donor blood
C