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11 Cards in this Set
- Front
- Back
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ABO type antibodies
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natural occuring IgM to blood group antigens
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Rh antibodies
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IgG acquired
does not cause acute hemoylsis |
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crossmatching blood
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mix patient serum vs donor RBC - test with direct antibody test
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antibody screen
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indirect coombs test
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transfusion reactions
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acute hemolytic transfusion reaction
delayed transfusion reaction - due to patient antibody reactivation febrile reaction due to WBC urticarial reaction to plasma protein anaphylactic transfusion reaction see with IgA TRALI - transfusion related acute lung injury Graft v Host antibodies to RBC platelet refractoriness autoimmune hemolytic anemia PTP probably transfusion related immunomodulation osmostic damage |
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acute hemolytic transfusion reaction
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usually due to patient mix up or error
see hypotension, teacolor urine, pink plasma |
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fresh frozen plasma
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useful in DIC, reversing warfarin
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cryoprecipitate
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factor VIII, source of fibrinogen
can use for hemophilia or cardiac surgery or DIC |
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rVIIa - recombinant activated factor VII
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developed to treat hemophlia A
bypass the need for factor VIII by activating VII |
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Packed RBCs
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1 unit increases hemoglobin 1 gram
for traumatic blood loss |
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platelet transfusion
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short shelf life give for people with supply issues, refractoriness, or sepsis
don't give to ITP, HIT, TTP, DIC, PTP |
