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12 Cards in this Set

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  • Back

Transport in mammals

Closed circulation : blood is pumped from the heart to arteries, veins and capillaries.


Blood passes the heart twice =double circulation (systemic and pulmonary)


Delivery of oxygenated blood quickly to all regions of the body


Blood reaches the tissues without being diluted by unoxygenated blood

Blood components

Defends against disease, transports respiratory gases


Plasma: 55% transports nutrients, waste, hormones, heat, dissolved proteins


Red/erythrocytes : transports oxygen and CO2


White/leucocytes: Lymphocytes and phagocytes digest bacteria


Platelets: result in clotting

Heart valves

Atrioventricular valves: right side is tricuspid valve, the left side is bicuspid, under huge pressure and supported by tendons


Semi lunar valves between ventricles and pulmonary artery (right) and aorta (left)

Heart

Hollow organ, contained in tightly fitting membrane: pericardium


Cardiac muscle consists of cylindrical columns of fibres , allowing for contraction in three dimensions, surrounded by plasma membrane: sarcolemma, connected by intercalated discs Myogenic origin

Coronary heart disease

Atherosclerosis: Damage to artery walls as fat strands and fibrous tissue are deposited under the endothelium


Raised blood pressure


Lesion formation = plaques and thrombus are often formed as a result of exposed blood platelets



Consequences of coronary heart disease

Embolus can cause blockage--> tissue deprived of oxygen from which it will die Problems in the coronary arteries can be fixed by heart by-pass operation (part of a blood vessel is taken from somewhere else so the blocked one can be passed) or coronary angioplasty (insert balloon or mesh into artery)

Heartbeat

Beats 75 times/minute (0.8 s for each contraction)


Systole: heart muscle contracts and diastole: the heart muscle relaxes


Stroke volume is the volume of blood forced from the ventricles into the aorta and pulmonary arteries. Each surge stretches the artery walls, which is the pulse.

Control of the heartbeat



pacemaker: a very small bit of the muscle in the right atrium --> electric pulses spread through both artia--> atrial systole (delay before AVN stops both contractions from happening simultaneously) -->

--> electric signal is picked up by the AVN, atrioventricular node at the base of the right atrium which is then passed by tiny conducting fibres called Purkeyne and fibres, collectively called bundles of his Bundles of his stimulates the ventricles from bottom up into contracting The heart has a relatively long rest period called refractory period (diastole)

Pacemaker

Amount of blood from heart = cardiac output=stroke volume*pulse rate




Regulated by Cardiovascular centre in the brain sends signals by two nerves: Sympathetic nerve which speeds up the rate of the heart + Vagus nerve which slows it down

Arteries

Aorta-->artery-->arteriole-->capillary-->venule-->vein-->venacava


thickest+ strongest walls, no valves


Main arteries have elastic fibres to stretch for high pulse, and to recoil and push the blood forward Arterioles have smooth muscles to regulate the flow of blood from arteries into capillaries.

Capillaries

tinytubes linking veins and arteries




thin walls of one layer of endothelial cells to allow for exchange between blood and tissue




no valves

Veins

Carry blood back to heart


Veinshave thin walls due to low pressure




Venules consist of one endothelium cell layer and a few smooth muscles




Veins have few elastic fibres because of low pressure, and have valves