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195 Cards in this Set

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  • Back
albumin
protein in blood; maintains the proper amount of water in the blood
antibody
(AB) Protein (immunoglobin) produced by lymphocytes in response to bacteria, viruses, or other antigens.
antigen
substance (usually foreign) that stimulates the production of an antibody
basophil
white blood cell containing granules that stain blue; associated with release of histamine and heparin
bilirubin
orange- yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells die
coagulation
blood clotting
colony-stimulating factor
CSF. protein thet stimulates the growth and proliferation of white blood cells (granulocytes)
differentiation
change in structure and function of a cell as it maures; specialization
electrophoresis
method of separating serum proteins by electrical charge
eosinophil
white blood cell containing granules that stain red; associated with allergic reaction
erythropoietin
EPO. hormone secreted by the kidneys that stimulates red blood cell formation
fibrin
protein threads that form the basis of a blood clot
fibrinogen
plasma protein that is converted to fibrin in the clotting process
globulin
plasma protein; alpha, beta, and gamma (immune) globulins are examples
granulocyte
white blood cell with numerous dark-staining granules: eosinophil, neutrophil, and basophil
hemoglobin
blood protein containing iron; carries oxygen in red blood cells
hemolysis
destruction or breakdown of blood (red blood cells)
heparin
anticoagulant found in blood and tissue cells
immune reaction
response of the immune system to foreign invasion
immunoglobulin
protein (globulin) with antibody activity; examples are IgG, IgM, IgA, IgE, IgD.
immun/o
combining form means protection
leukocyte
white blood cell
lymphocyte
mononuclear leukocyte that produces antibodies
macrophage
monocyte that migrates from the blood to tissue spaces. As a phagocyte, it enguls foreign material and debris
megakaryocyte
large platelet precursor cell found in the bone marrow
monocyte
leukocyte with one larege nucleus
monocyte
it is a cell that engulfs foreign material and debris
mononuclear
pertaining to a cell (leukocyte) with a single round nucleaus
neutrophil
granulocytic leukocyte formed in bone marrow. it is a phagocytic tissue-fighting cell
polymorphonuclear leukocyte
neutrophil is also called what?
plasma
liquid portion of the blood; contains water, proteins, salts, nutrients, hormones, and vitamins
plasmapheresis
removal of plasma from withdrawal blood by centrifuge. Collected cells are retransfused back into the donor. Fresh- frozen plasma or salt solution is used to replace withdrawn plasma
platelet
small blood fragment that collects at sites of injury to begin the clotting process
prothrombin
plasma protein; converted to thrombin in the clotting process
reticulocyte
immature erythrocyte. a network of strands (reiculin) is seen after staining the cell with special dyes
Rh factor
antigen on red blood cells of Rh- postive (RH+) individuals. The factor was first identified in the blood of a rhesus monkey
serum
plasma minus clotting proteins and cells. clear, yellowish fluid that separates from blood when it is allowed to clot. it is formed form plasma, but does not contain protein- coagulation factors
stem cell
unspecialized cell that gives rise to mature, specialized forms.
hematopoietic stem cell
is the progenitor for all different types of blood cells
thrombin
enzyme that converts fibrinogen to fibrin during coagulation
thrombocyte
a platelet
bas/o
combining form for base (alkaline, the opposite of acid)
basophil
cell, or histologic element staining readily with basic dyes
chrom/o
combining form for color
-phil
a suffix means attraction to
hypochromic
pertaining to less than normal color
coagul/o
combining form for clotting
anticoagulant
acting to suppress, delay, or nullify blood coagulation, or an agent that does this
coagulopathy
A disease affecting the coagulability of the blood
cyt/o
cell
cytology
study of cells
eosin/o
red, dawn, rosy
eosinophil
A type of white blood cell containing cytoplasmic granules that are easily stained by eosin or other acid dyes
erythroblast
immature red blood cells
-blast
suffix that means immature
granul/o
combining form for granules
granulocyte
Any of a group of white blood cells having granules in the cytoplasm
hem/o
combining form for blood
hemolysis
destruction or breakdown of red blood cells
hematrocrit
means a certain volume of blood separation
-crit
suffix means to separate
hemoglobin/o
combining form for hemoglobin
hemoglobinopahty
disorder disease of hemoglobin
is/o
combining form for same, equal
anisocytosis
unequal size increase in the number of cells
anis/o
combining form for size
-cytosis
suffix means an increase in the number of cells
kary/o
combining form for nucleus
megakaryocyte
it is a large cell with a greatly lobulated nucleus
leuk/o
combining form for white
leukopenia
abnormal condition of white blood cells
mon/o
combining form means one, single
monocyte
has a single cell nucleus
morph/o
combining form for shape, form
morphology
study of shapes or forms
myel/o
combining form for bone marrow
myeloblast
immautre bone marrow
-blast
suffix means immature
myelodysplasia
bads formation of the bone marrow
neutr/o
combining form for neutral
neutropenia
neutral blood condition (neither base nor acid)
nucle/o
combining form for nucleus
polymorphonuclear
having a nucleus so deeply lobed or so divided as to appear to be multiple
phag/o
combining form for eat, swallow
phagocyte
is an eating cell
poikil/o
combining form for varied, irregular
poikilocytosis
abnormal irregularity of a cell
sider/o
combining form for iron
sideropenia
An abnormally low level of iron in the blood serum
spher/o
combining form for globe, round
spherocytosis
abnormal condition of round cell
thromb/o
combining form for clot
thrombocytopenia
is an abnormal drop in the number of blood cells involved in forming blood clots
-apheresis
suffix means removal, a carrying away
plasmapheresis
removal of plasma
leukapheresis
removal of white blood cell
monoblast
embryonic singel cell
macrocytosis
large abnormal condition of the cells
macro-
prefix means large
microcytosis
small abnormal condition of cell
micro-
prefix means small
-globulin
suffix for immunoglobulin
-lytic
suffix means pertaining to destruction
leukemia
white blood condition
hemoglobin
means white protein
-oid
suffix means derived from
thrombolytic therapy
used to dissolve clots
myeloid
means derived from the bone marrow
-osis
suffix means abnormal condition
thrombosis
abnormal condition of the clotting cell
-penia
suffix means deficiency
granulocytopenia
deficiency in granule cell
pancytopenia
abnormal depression of all the cellular elements of the blood
macrophage
a large phagocyte that destroys worn-out red blood cells and foreign material
-phage
a suffix means eat, swallow
-philia
a suffix means carrying, transmission
-poiesis
a suffix means formation
hematopoiesis
a formation of blood
erythropoiesis
formation of red blood cells
myelopoiesis
formation of bone marrow
-stasis
a suffix means stop, control
hemostatis
stopping of blood
anemia
deficiency in erythrocytes or hemoglobin
aplastic anemia
failure of blood cell production in the bone marrow
hemolytic anemia
reduction in red cells due to excessive destruction
pernicious anemia
lack of mature erythrocytes caused by inability to absorb vitamin B12 into the body
sickle cell anemia
hereditary condition characterized by abnormal sickle shape of erythrocytes and by hemolysis
thalassemia
inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background
hemochromatosis
excess iron deposits throughout the body
polycythemia vera
general increase in red blood cells (erythremia)
hemophilia
excessive bleeding caused by hereditary lack of blood clotting factors necessary for blood clotting
purpura
multiple pinpoint hemorrhages and accumulation of blood under the skin
petechiae
are tiny purple or red flat spots appearing on the skin as a result of hemorrhages
ecchymoses
are larger blue or purplish patches on the skin (bruises)
autoimmune thrombocytopenic purpura
is a condition in which a patient makes an antibody that destroys plateles
leukemia
increase in cancerous white blood cells (leukocytes)
acute myelogenous (myelocytic) leukemia
AML. immature granulocytes (myeloblasts) predominate
Acute lymphoblastic leukemia
ALL. lymphoblasts (immature lymphocytes) predoniate. is a disease of children and young adults
chronic myelogenous (myelocytic) leukemia
CML. both mature and immature granulocytes are present in large numbers in the marrow and bloodstream
chronic lymphocytic leukemia
CLL. abnormal numbers of relatively mature lymphocytes predonminate in the marrow, lymph nodes, and spleen
remission
disappearance of signs and symptoms of disease
relapse
occurs when disease symptoms and signs reappear, necessitating further treatment
granulocytosis
abnormal increase in granulocytes in the blood
mononucleosis
infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph nodes
epstein-barr virus
EBV
multiple myeloma
malignant neoplasm of bone marrow
antiglobulin test
test of the presence of antibodies that coat and damage erythrocytes
bleeding time
time required for blood to stop flowing from a tiny puncture wound
coagulation time
time required for venous blood to clot in a test tube
complete blood count
CBC. determination of numbers of blood cells, hemoglobin concentration, hematocrit, and red cell values- MCH, MCV, MCHC
erythrocyte sedimentation rate
ESR. speed at which erythrocytes settle out of plasma
hematocrit
Hct. percentage of erythrocytes in a volume of blood
hemoglobin test
H, Hg, Hgb, HGB. total amount of hemoglobin in a sample of peripheral blood
platelet count
number of platelets per cubic millimeter (mm3) or microliter of blood
prothrombin time
PT. test of the ability of blood to clot
red blood cell count
RBC. number of erythrocytes per cubic millimeter (mm3) or microliter of blood
red blood cell morphology
microscopic examination of a stained blood smear to determine the shape of individual red cells
white blood cell count
WBC. number of leukocytes per cubic millimeter or microliter of blood
white blood cell deferential (count)
percentage of different types of leukocytes in the blood
apharesis
separation of blood into component parts and removal of a select portion from the blood
blood transfusion
whole blood or cells are taken from a donor and infused into a patient
bone marrow biopsy
microscopic examination of a core of bone marrow removed with a needle
hematopoietic stem cell transplantation
peripheral stem cells from a compatible donor are administered to a recipient
antibody
Ab
autologous bone marrow transplantation
ABMT. patient serves as his or her own donor for stem cells
ABO
four main blood types
absolute neutrophil count
ANC. this is the total WBC times a measure of the number of neutrophils present in the blood
autologous stem cell transplantation
ASCT
bands
immature white blood cells (granulocytes)
basophils
baso means
bone marrow transplantation
BMT means
disseminated intravascular coagulation
DIC. bleeding disorder marked by reduction in blood clotting factors due to their use and depletion for intravascular clotting
differential count (white blood cells)
diff
eosinophils
eos
iron
Fe
granulocyte colony-stimulating factor
G-CSF. promotes neutrophil production
granulocyte-macrophage colony-stimulating factor
GM-CSF. promotes myeloid progenitor cells with differentiation to granulocytes
gram per deciliter
g/dL
graft-versus-host disease
GVHD. immune reaction of donor's cells to recipient's tissue
hairy cell leukemia
HCL. abnormal lmyphocytes accumulate in bone marrow, leading to anemia, thrombocytopenia, neutropenia, and infection
hemoglobin
Hgb, HGB
hemoglobin and hematocrit
H and H
human leukocyte antigen
HLA
immunoglobulins
IgA, IgD, IgE, IgG, IgM
lymphoctyes
lymphs
mean corpuscular hemnoglobin
MCH. average amount of hemoglobin per cell
mean corpuscular hemoglobin concentration
MCHC. average concentration of hemoglobin in a single red cell
mean corpuscular volume
MCV. average volume or size of a single red blood cell
monocyte
mono
polymorphonuclear leukocytes; neutrophils, eosinophils, basophils
polys, PMNs, PMNLs
partial thromboplastin time
PTT
erythrocyte sedimentation rate
sed rate
segmented, mature white blood cells (neutrophils)
segs
sequential multiple analyzer computer
SMAC. an automated chemistry system that determines substances in serum
within normal limits
WNL