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195 Cards in this Set
- Front
- Back
albumin
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protein in blood; maintains the proper amount of water in the blood
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antibody
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(AB) Protein (immunoglobin) produced by lymphocytes in response to bacteria, viruses, or other antigens.
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antigen
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substance (usually foreign) that stimulates the production of an antibody
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basophil
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white blood cell containing granules that stain blue; associated with release of histamine and heparin
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bilirubin
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orange- yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells die
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coagulation
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blood clotting
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colony-stimulating factor
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CSF. protein thet stimulates the growth and proliferation of white blood cells (granulocytes)
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differentiation
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change in structure and function of a cell as it maures; specialization
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electrophoresis
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method of separating serum proteins by electrical charge
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eosinophil
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white blood cell containing granules that stain red; associated with allergic reaction
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erythropoietin
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EPO. hormone secreted by the kidneys that stimulates red blood cell formation
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fibrin
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protein threads that form the basis of a blood clot
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fibrinogen
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plasma protein that is converted to fibrin in the clotting process
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globulin
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plasma protein; alpha, beta, and gamma (immune) globulins are examples
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granulocyte
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white blood cell with numerous dark-staining granules: eosinophil, neutrophil, and basophil
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hemoglobin
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blood protein containing iron; carries oxygen in red blood cells
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hemolysis
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destruction or breakdown of blood (red blood cells)
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heparin
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anticoagulant found in blood and tissue cells
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immune reaction
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response of the immune system to foreign invasion
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immunoglobulin
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protein (globulin) with antibody activity; examples are IgG, IgM, IgA, IgE, IgD.
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immun/o
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combining form means protection
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leukocyte
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white blood cell
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lymphocyte
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mononuclear leukocyte that produces antibodies
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macrophage
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monocyte that migrates from the blood to tissue spaces. As a phagocyte, it enguls foreign material and debris
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megakaryocyte
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large platelet precursor cell found in the bone marrow
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monocyte
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leukocyte with one larege nucleus
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monocyte
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it is a cell that engulfs foreign material and debris
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mononuclear
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pertaining to a cell (leukocyte) with a single round nucleaus
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neutrophil
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granulocytic leukocyte formed in bone marrow. it is a phagocytic tissue-fighting cell
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polymorphonuclear leukocyte
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neutrophil is also called what?
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plasma
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liquid portion of the blood; contains water, proteins, salts, nutrients, hormones, and vitamins
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plasmapheresis
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removal of plasma from withdrawal blood by centrifuge. Collected cells are retransfused back into the donor. Fresh- frozen plasma or salt solution is used to replace withdrawn plasma
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platelet
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small blood fragment that collects at sites of injury to begin the clotting process
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prothrombin
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plasma protein; converted to thrombin in the clotting process
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reticulocyte
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immature erythrocyte. a network of strands (reiculin) is seen after staining the cell with special dyes
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Rh factor
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antigen on red blood cells of Rh- postive (RH+) individuals. The factor was first identified in the blood of a rhesus monkey
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serum
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plasma minus clotting proteins and cells. clear, yellowish fluid that separates from blood when it is allowed to clot. it is formed form plasma, but does not contain protein- coagulation factors
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stem cell
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unspecialized cell that gives rise to mature, specialized forms.
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hematopoietic stem cell
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is the progenitor for all different types of blood cells
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thrombin
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enzyme that converts fibrinogen to fibrin during coagulation
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thrombocyte
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a platelet
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bas/o
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combining form for base (alkaline, the opposite of acid)
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basophil
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cell, or histologic element staining readily with basic dyes
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chrom/o
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combining form for color
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-phil
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a suffix means attraction to
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hypochromic
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pertaining to less than normal color
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coagul/o
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combining form for clotting
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anticoagulant
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acting to suppress, delay, or nullify blood coagulation, or an agent that does this
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coagulopathy
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A disease affecting the coagulability of the blood
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cyt/o
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cell
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cytology
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study of cells
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eosin/o
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red, dawn, rosy
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eosinophil
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A type of white blood cell containing cytoplasmic granules that are easily stained by eosin or other acid dyes
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erythroblast
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immature red blood cells
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-blast
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suffix that means immature
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granul/o
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combining form for granules
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granulocyte
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Any of a group of white blood cells having granules in the cytoplasm
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hem/o
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combining form for blood
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hemolysis
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destruction or breakdown of red blood cells
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hematrocrit
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means a certain volume of blood separation
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-crit
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suffix means to separate
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hemoglobin/o
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combining form for hemoglobin
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hemoglobinopahty
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disorder disease of hemoglobin
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is/o
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combining form for same, equal
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anisocytosis
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unequal size increase in the number of cells
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anis/o
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combining form for size
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-cytosis
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suffix means an increase in the number of cells
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kary/o
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combining form for nucleus
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megakaryocyte
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it is a large cell with a greatly lobulated nucleus
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leuk/o
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combining form for white
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leukopenia
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abnormal condition of white blood cells
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mon/o
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combining form means one, single
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monocyte
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has a single cell nucleus
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morph/o
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combining form for shape, form
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morphology
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study of shapes or forms
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myel/o
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combining form for bone marrow
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myeloblast
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immautre bone marrow
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-blast
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suffix means immature
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myelodysplasia
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bads formation of the bone marrow
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neutr/o
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combining form for neutral
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neutropenia
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neutral blood condition (neither base nor acid)
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nucle/o
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combining form for nucleus
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polymorphonuclear
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having a nucleus so deeply lobed or so divided as to appear to be multiple
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phag/o
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combining form for eat, swallow
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phagocyte
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is an eating cell
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poikil/o
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combining form for varied, irregular
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poikilocytosis
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abnormal irregularity of a cell
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sider/o
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combining form for iron
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sideropenia
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An abnormally low level of iron in the blood serum
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spher/o
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combining form for globe, round
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spherocytosis
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abnormal condition of round cell
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thromb/o
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combining form for clot
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thrombocytopenia
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is an abnormal drop in the number of blood cells involved in forming blood clots
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-apheresis
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suffix means removal, a carrying away
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plasmapheresis
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removal of plasma
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leukapheresis
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removal of white blood cell
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monoblast
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embryonic singel cell
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macrocytosis
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large abnormal condition of the cells
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macro-
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prefix means large
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microcytosis
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small abnormal condition of cell
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micro-
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prefix means small
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-globulin
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suffix for immunoglobulin
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-lytic
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suffix means pertaining to destruction
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leukemia
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white blood condition
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hemoglobin
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means white protein
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-oid
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suffix means derived from
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thrombolytic therapy
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used to dissolve clots
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myeloid
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means derived from the bone marrow
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-osis
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suffix means abnormal condition
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thrombosis
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abnormal condition of the clotting cell
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-penia
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suffix means deficiency
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granulocytopenia
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deficiency in granule cell
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pancytopenia
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abnormal depression of all the cellular elements of the blood
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macrophage
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a large phagocyte that destroys worn-out red blood cells and foreign material
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-phage
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a suffix means eat, swallow
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-philia
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a suffix means carrying, transmission
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-poiesis
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a suffix means formation
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hematopoiesis
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a formation of blood
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erythropoiesis
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formation of red blood cells
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myelopoiesis
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formation of bone marrow
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-stasis
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a suffix means stop, control
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hemostatis
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stopping of blood
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anemia
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deficiency in erythrocytes or hemoglobin
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aplastic anemia
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failure of blood cell production in the bone marrow
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hemolytic anemia
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reduction in red cells due to excessive destruction
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pernicious anemia
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lack of mature erythrocytes caused by inability to absorb vitamin B12 into the body
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sickle cell anemia
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hereditary condition characterized by abnormal sickle shape of erythrocytes and by hemolysis
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thalassemia
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inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background
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hemochromatosis
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excess iron deposits throughout the body
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polycythemia vera
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general increase in red blood cells (erythremia)
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hemophilia
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excessive bleeding caused by hereditary lack of blood clotting factors necessary for blood clotting
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purpura
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multiple pinpoint hemorrhages and accumulation of blood under the skin
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petechiae
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are tiny purple or red flat spots appearing on the skin as a result of hemorrhages
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ecchymoses
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are larger blue or purplish patches on the skin (bruises)
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autoimmune thrombocytopenic purpura
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is a condition in which a patient makes an antibody that destroys plateles
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leukemia
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increase in cancerous white blood cells (leukocytes)
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acute myelogenous (myelocytic) leukemia
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AML. immature granulocytes (myeloblasts) predominate
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Acute lymphoblastic leukemia
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ALL. lymphoblasts (immature lymphocytes) predoniate. is a disease of children and young adults
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chronic myelogenous (myelocytic) leukemia
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CML. both mature and immature granulocytes are present in large numbers in the marrow and bloodstream
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chronic lymphocytic leukemia
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CLL. abnormal numbers of relatively mature lymphocytes predonminate in the marrow, lymph nodes, and spleen
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remission
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disappearance of signs and symptoms of disease
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relapse
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occurs when disease symptoms and signs reappear, necessitating further treatment
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granulocytosis
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abnormal increase in granulocytes in the blood
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mononucleosis
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infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph nodes
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epstein-barr virus
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EBV
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multiple myeloma
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malignant neoplasm of bone marrow
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antiglobulin test
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test of the presence of antibodies that coat and damage erythrocytes
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bleeding time
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time required for blood to stop flowing from a tiny puncture wound
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coagulation time
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time required for venous blood to clot in a test tube
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complete blood count
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CBC. determination of numbers of blood cells, hemoglobin concentration, hematocrit, and red cell values- MCH, MCV, MCHC
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erythrocyte sedimentation rate
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ESR. speed at which erythrocytes settle out of plasma
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hematocrit
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Hct. percentage of erythrocytes in a volume of blood
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hemoglobin test
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H, Hg, Hgb, HGB. total amount of hemoglobin in a sample of peripheral blood
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platelet count
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number of platelets per cubic millimeter (mm3) or microliter of blood
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prothrombin time
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PT. test of the ability of blood to clot
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red blood cell count
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RBC. number of erythrocytes per cubic millimeter (mm3) or microliter of blood
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red blood cell morphology
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microscopic examination of a stained blood smear to determine the shape of individual red cells
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white blood cell count
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WBC. number of leukocytes per cubic millimeter or microliter of blood
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white blood cell deferential (count)
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percentage of different types of leukocytes in the blood
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apharesis
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separation of blood into component parts and removal of a select portion from the blood
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blood transfusion
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whole blood or cells are taken from a donor and infused into a patient
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bone marrow biopsy
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microscopic examination of a core of bone marrow removed with a needle
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hematopoietic stem cell transplantation
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peripheral stem cells from a compatible donor are administered to a recipient
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antibody
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Ab
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autologous bone marrow transplantation
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ABMT. patient serves as his or her own donor for stem cells
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ABO
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four main blood types
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absolute neutrophil count
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ANC. this is the total WBC times a measure of the number of neutrophils present in the blood
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autologous stem cell transplantation
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ASCT
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bands
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immature white blood cells (granulocytes)
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basophils
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baso means
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bone marrow transplantation
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BMT means
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disseminated intravascular coagulation
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DIC. bleeding disorder marked by reduction in blood clotting factors due to their use and depletion for intravascular clotting
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differential count (white blood cells)
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diff
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eosinophils
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eos
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iron
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Fe
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granulocyte colony-stimulating factor
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G-CSF. promotes neutrophil production
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granulocyte-macrophage colony-stimulating factor
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GM-CSF. promotes myeloid progenitor cells with differentiation to granulocytes
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gram per deciliter
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g/dL
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graft-versus-host disease
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GVHD. immune reaction of donor's cells to recipient's tissue
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hairy cell leukemia
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HCL. abnormal lmyphocytes accumulate in bone marrow, leading to anemia, thrombocytopenia, neutropenia, and infection
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hemoglobin
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Hgb, HGB
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hemoglobin and hematocrit
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H and H
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human leukocyte antigen
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HLA
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immunoglobulins
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IgA, IgD, IgE, IgG, IgM
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lymphoctyes
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lymphs
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mean corpuscular hemnoglobin
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MCH. average amount of hemoglobin per cell
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mean corpuscular hemoglobin concentration
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MCHC. average concentration of hemoglobin in a single red cell
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mean corpuscular volume
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MCV. average volume or size of a single red blood cell
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monocyte
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mono
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polymorphonuclear leukocytes; neutrophils, eosinophils, basophils
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polys, PMNs, PMNLs
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partial thromboplastin time
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PTT
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erythrocyte sedimentation rate
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sed rate
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segmented, mature white blood cells (neutrophils)
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segs
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sequential multiple analyzer computer
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SMAC. an automated chemistry system that determines substances in serum
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within normal limits
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WNL
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