Blood-Modifying, Antineoplastics, And Immunosuppressive Drugs

Front 1

Where are RBC's formed?

Back 1

In the bone marrow

Front 2

In response to what?

Back 2

Erythropoieten

Front 3

Hemoglobin = ?

Back 3

Protein and Iron (Fe++)

Front 4

Iron deficiency anemia is rare in all animals except?

Back 4

Baby Pigs!

Baby Pig Anemia

Front 5

What are Hematinics?

Back 5

Substances that promote an increase in O2 carrying capacity of blood

Front 6

What are two iron supplements?

Back 6

Injectable Iron Dextran

Pet Tinic

Front 7

What are the human erythropoietin products?

Back 7

Epogen, Procit

Front 8

What is the NEW Erythropoietin drug called?

Back 8

darbepoetin alpha

Front 9

What are erthropoetein drugs used for?

Back 9

anemia of chronic renal failure in dogs and cats

Front 10

What is the trade name of the bovine blood substitute product?

Back 10

Oxyglobin

(Hemoglobin glutamer-200)

Front 11

What are the advantages of Oxyglobin over blood products?

Back 11

-Long Shelf life

- No need for blood typing

- No risk of disease transmission

Front 12

What is the name of the Androgen drug?

Back 12

Winstrol-V

Stanozolol

Front 13

What is Heparin used for in vitro?

Back 13

Anticoagulant for pt samples

Front 14

What is Heparin used for in vivo?

Back 14

heparin flush for catheters

Tx for DIC

Tx for HCM

Front 15

What is the in vitro use of EDTA?

Back 15

Anticoagulant of choice for CBC

Front 16

What is the in vivo use of EDTA?

Back 16

lead poisoning

Front 17

Which coagulation factors are Vit K Dependant?

Back 17

2, 7, 9, and 10

Front 18

What is the MOA of coumarin derivatives?

Back 18

Ties up Vit K

Front 19

What is the Coumarin derivate monitoring test?

Back 19

PT - Prothrombin Time

Front 20

What does ACD stand for?

Back 20

Acid Citrate Dextrose

Front 21

What does CPDA stand for?

Back 21

Citrate Phosphate Dextrose Adenine

Front 22

What are they used for?

Back 22

Anticoagulants for blood collection

Front 23

What is the antiplatelet drug?

Back 23

Asprin

Front 24

What are the clinical uses of Aspirin?

Back 24

post adulticide hw tx in dogs

HCM in cats

Front 25

What do hemostatics do?

Back 25

Promote blood clotting

Front 26

What are topical hemostatics used for?

Back 26

Control capillary or small blood vessel bleeding

Front 27

Topical hemostatics work in one of two ways. What are they?

Back 27

Provide framework for clot

coagulating blood protein to start coagulation cascade

Front 28

What are the topical hemostatic framework substances?

Back 28

Gelfoam

Clotisol Liquid

Silver Nitrate

Front 29

What is the Anticoagulant Antagonist dug? What is it used for?

Back 29

Vit K 1

Rodenticide Poisoning

Front 30

What are the 3 goals of Antineoplastic Drugs?

Back 30

1. Keep Neoplasia under control

2. Relieve Pain

3. Destroy microscopic metastases

Front 31

What effects does Antineoplastic Drugs have on neoplasms?

Back 31

reduce tumor size

relieve pain

destroy microscopic metastases

Front 32

What are the 3 cancer characteristics?

Back 32

Initiation

Promotion

Progression

Front 33

What are the 6 fundamental cancer characteristics?

Back 33

Able to produce cell growth signals

Insenstive to antigrowth signals

able to resist programed cell death

ulimited potential to replicate

able to form new blood vessels to nurture mass

able to metastasize

Front 34

Steroids such as prednisone are used in high doses for what?

Back 34

Lymphoma

Front 35

What is Nadir?

Back 35

lowest wbc count

Front 36

What is the most common immune mediated disease?

Back 36

IMHA

Front 37

What are the immunosuppressive drugs?

Back 37

prednisone

azathioprine ( Imuran)

cyclosporine

metronidazole

cyclophosphamide (Cytoxan)