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13 Cards in this Set
- Front
- Back
state how many oxygen molecules hemoglobin can carry
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4
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list the sites on hemoglobin where oxygen and carbon dioxide bind
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oxygen binds on the iron center of heme
carbon dioxide binds to amino group of globin |
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list the partial pressure of oxygen and carbon dioxide in alveoli
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pO2= 100 mm Hg
pCO2= 40 mm Hg |
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list the partial pressure of oxygen and carbon dioxide in pulmonary arteries
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pO2= 40 mm Hg
pCO2= 45 mm Hg |
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list the partial pressure of oxygen and carbon dioxide in pulmonary veins
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pO2= 100 mm Hg
pCO2= 40 mm Hg |
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list the partial pressure of oxygen and carbon dioxide in systemic arteries
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pO2=100 mm Hg
pCO2= 40 mm Hg |
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list the partial pressure of oxygen and carbon dioxide in systemic veins
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pO2= 40 mm Hg
pCO2= 40 mm Hg |
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list the 2 mechanisms by which oxygen is transported in the blod
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dissolved in plasma & on hemoglobin
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list 4 factors which affect hemoglobin affinity for oxygen and how
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pO2
pH pCO2 temperature |
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define the "Bohr effect" and "Haldane effect"
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Bohr Effect: an increase in blood carbon dioxide level or a decrease in pH causes hemoglobin to bind to oxygen with less affinity.
Haldane Effect: the higher the pO2, the lower the hemoglobin affinity for CO2 |
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list the 3 mechanisms by which carbon dioxide is transported in the blood
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dissolved in plasma, on hemoglobin, as HCO3- [bicarbonate]
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describe what happens to carbon dioxide within the red blood cells
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as CO2 diffuses into systemic capillaries & enters RBCs, it reacts with H2O in the presence of the enzyme carbonic anhyrdase to form carbonic acid, which dissociates into H+ ions and bicarbonate (HCO3-)
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define the "chloride shift"
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as HCO3- moves into plasma, chloride ions move from plasma to RBC
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