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18 Cards in this Set

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Purpose of Blood Gas Analysis
1. Determine acid-base balance
2. Assess adequacy of alveolar ventilation
3. Assess oxygenation status
Measurement obtained and purpose:
pH
1. Determine the acidity (acidosis) or alkalinity (alkalosis) of the blood
2. Assess the concentration of hydrogen ions (the acid-base balance) in the blood
Measurement obtained and purpose:
PaCO2
1. Evaluate the adequacy of alveolar ventilation
2. Determine how well the lungs are able to remove carbon dioxide
3. Assess the respiratory component of acid-base balance
Measurement obtained and purpose:
HCO3
1. Indicates the level of base in the blood
2. Assess the metabolic component of acid-base balance
Measurement obtained and purpose:
BE
1. Determines if there is an excess of base, expressed as a positive number (+)
2. Determines if there is a deficit of base expressed as a negative number (-)
Measurement obtained and purpose:
PaO2
1. Evaluate the adequacy of oxygenation
2. Reflects the amount of oxygen dissolved in the blood
Normal arterial values
pH 7.35 - 7.45
PaCO2 35-45 mmHg
HCO3 22 - 26 mEq/L
BE +or- 2 mEq/L
PaO2 80 - 100 mmHg
SaO2 97% (>90%)
Arterial blood vs. venous blood
Arterial reflects the status of the whole body
Venous reflects the status of the organ/muscle from where it is obtained
pH definition
negative logarithm of the hydrogen ion concentration (H+) = 0.000 000 1 = 7
Acid
Substances capable of donating a hydrogen ion in a chemical reaction
Base
Substances capable of accepting a hydrogen ion in a chemical reaction
H+ and pH
The greater the concentration of H+ the lower the pH = inverse relationship
pH homeostasis
The body does what it can to achieve a balance between the KIDNEYS and the LUNGS for the purpose of trying to normalize the pH through: Acid, Base, Buffers
Regulation of pH
1. Kidneys regulate the level of base HCO3
2. Lungs regulate the level of acid H2CO3 (PCO2)
pH = Base/Acid
Base = HCO3 (bicarbonate) - kidneys (metabolic)

Acid = H2CO3 (carbonic acid) -
Lungs (respiratory)
Fixed Acids #1
1. Produced as a result of normal body metabolism
2. Cannot be converted into gases
3. Kidneys are responsible for maintaining normal fixed acid homeostasis
4. Several conditions can result in an abnormal increase in fixed acids (i.e., diabetes, hypoxia)
Fixed Acids #2
- Sulfuric Acid
- Phosphoric Acid
- Ketoacids
- Lactic Acid
pH ranges
in arterial blood = 7.40
normal range = 7.35 - 7.45
Acidosis = pH < 7.35
Alkalosis = pH > 7.45