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9 Cards in this Set

  • Front
  • Back
Blood transports:
O2 from lungs
CO2 to lungs
nutrients from GI tract
waste products from cells
hormones from endocrine glands
Blood regulates:
pH through buffers
body temp through heat-absorbing &coolant properties of H2O
osmoic relations through Na content
Blood protects against:
blood loss through clotting
foreign microbes and toxins through WBC actions
Erythrocytes (Red Blood Cells)
Biconcave discs which at maturity lack a nucleus
Erythrocyte characteristics
rellatively large surface area: volume ratio at maturity not only lack nucleus but also lack mitochondria, microtubules, ER and protein synthesizing ability
primary function-transport respiratory gases
Erythrocyte production
early weeks embryonic life: yolk sac
middle trimester: liver and spleen
later gestation/after birth: bone marrow
age 5: all marrow
adult: proximal epiphyses of humerus and femur, and marrow of the flat bone of he cranium, ribs, sternum and body of vertebrae
RBC membrane: osmotic relationships
RBCs-hypotonic env.-membrane ruptures-hemolysis or laking
RBCs-hypertonic env.-cell shrinks-crenation or plasmolysi
Destruction of RBCs
life span:120days
destroyed by reticuloendothelial cells in the liver and spleen
Regulation of BRC production
any decrease in the oxygen carrying capacity of the tissues results in an increase in RBC production eg anemia, hemorrhage, high altiude, destruction of major portions of bone marrow leading to hyperplasia of the remaining bone marrow
NOTE: its not the concentration of RBCs but the oxygen carrying capacity that controls the rate of RBC production