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56 Cards in this Set

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  • Back
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Blood is the only?

Fluid tissue in the body

What type of tissue is blood?

Connective tissue

Average adult has around how many liters of blood?

5 L

Is blood thicker than water?

Yes about five times thicker than water (viscosity)

What vital substances does blood transport ?

Blood distributes heat and transports nutrients, gases, etc.

What three parts is a whole blood made up of?

Plasma, RBCs, WBCs

Plasma consist of?

Water, proteins, urea, Uric acid, electrolytes, O2, CO2, nutrients like glucose and cholesterol, hormones

% RBCs in sample of whole blood is the?

Hematocrit

What is he Hematopoiesis?

The production of formed elements RBCs, wbc’s, and platelets


Where? Red bone marrow especially in flat bones like sternum cranial cap, ilium, head of the femur and humerus.


How? Or blood cells come from Hematopoietic stem cells

Stem cells can?

. Give rise to more stem cells.


.Give rise to more specialized or differentiated cells in response to Hematopoietic growth factors.


. Lymphoid stem cells


. Myeloid stem cells

Lymphoid stem cells give rise to?

Lymphocytes

MyEloid stem cells give rise to?

all other types of formed elements red blood cells, other types of white blood cells and platelets

Erythrocytes are?

RBC’s

No nucleus or organelles in mature?

RBC’s

Can RBCs divide?

No

RBCs are filled with?

Hemoglobin to carry O2 and CO2

Erythropoieses occurs where?

In red bone marrow

What is ERYHTROPOIESIS?

Rbc formation

Average lifetime for RBCs?

120 days

Average lifetime for RBCs?

120 days

Low blood 02 calls his kidneys and liver to release the EPO (erythropoietin) which stimulates RBC production what other things can Stimulate EPO release?

Heavy bleeding, Hi altitude, iron deficiency, intense exercise.

What is anemia?

Condition in which the O2 carrying capacity of the blood is reduced, due to deficiency of RBCs or hemoglobin.

What is blood doping?

. Drawing out RBCs then reinjecting before major athletic event.


. Increases hematocrit to about 60%


.Increases O2 caring capacity.


over a 25% increase in O2 carried/100 ML’s


. Enhances endurance and speed

Excessive RBC distraction means?

Bilirubin accumulates in blood =Jaundice

What is leukocytes function?

Kills, immobilizes, or removes pathogen‘s.

What is leukocytes function?

Kills, immobilizes, or removes pathogen‘s.

Our leukocytes considered True cells?

Yes. (only true cell)

What is leukocytes function?

Kills, immobilizes, or removes pathogen‘s.

Our leukocytes considered True cells?

Yes. (only true cell)

Where do leukocytesPerform their work?

Outside of blood vessels.


...Diapedesis -WBC’s slip out a blood vessel’s.


...Positive Chemotaxis follow chemical trail left by other wbc’s or damaged cells.

Classification of the five leukocytes

Granulocytes:Have granules filled with hydrolytic enzymes or anti-microbial proteins in cytoplasm


. Neutrophil


. Eosinophils


. Basophils


Agranulocytes: no granules in cytoplasm.


. Monocytes


. Lymphocytes(T & B)

Never let monkeys eat bananas

Neutrophils

Small, light purple granules


First to arrive at infection site


Strong phagocytes


Elevated in bacterial infections

Eosinophils

Course granules deep red and acid stain


Moderate allergic reaction


Defend against parasitic worm infestation


Elevated in parasitic worm infestation and allergic reactions

Basophils

Large granules stain deep blue in basic stain


Granular’s can obscure the view of nucleus


Release histamine to stimulate inflammation


Release heparin to stop blood from clotting


Similar to Eosinophils in size and shape of nuclei

Monocytes

Largest of the WBCs



Agranulocyte


Leave bloodstream to become macrophages


Live for weeks to months

Lymphocytes

Slightly larger than RBCs smallest wbc


Surrounded by thin rim of cytoplasm A granulocytes


T cells and B cells are major types of both important in immunity


T cells directly attack pathogen‘s, tumor cells


B cells produce anti-bodies


May live for years

Functions of WBCs

Phagocytosis – engulfing and digestion of pathogen’s neutrophils and monocytes are most mobile and active phagocytes.


Inflammatory response – reaction that restricts spread of infection promoted by basophils by secretion of heparin and histamine, involves swelling and increased capillary permeability

Platelets (thrombocytes)

Help in hemostasis in damage blood cells by sticking to broken services.(stoppage of bleeding)


Release serotonin, which causes smooth muscle in walls of broken blood vessel‘s to contract(this reduces blood flow)

Plasma

Blood plasma


Clear, straw-colored


Liquid portion of blood


55% of blood volume


92% water contains organic and inorganic chemicals


Transports nutrients, gases, hormones and vitamins


Helps regulate fluid and electrolyte balance and maintain pH

Most important blood gases are?

Oxygen and carbon dioxide

Plasma nutrients are?

Amino acids


Simple sugars


Nucleotides


Lipids– Fats(triglycerides), phospholipids, cholesterol

Electrolytes found in blood plasma?

Sodium


Potassium


Calcium


Magnesium


Chloride


Bicarb


Phosphate


Sulfate


.Sodium and chloride or most abundant electrolytes

Plasma electrolytes contain a

.Variety of ions calledElectrolytes, since they ionize in water, and can conduct electricity that have a charge.


.They are absorbed from the intestines or released as byproducts of Cellular metabolism

What is hemostasis?

The stopping of bleeding at the blood vessel.

What are the three major processes that occur in hemostasis in the correct order?

1. Vascular spasm Dash smooth muscle contraction causing vasoconstriction slows blood loss/allows time for steps two and three


2. Platelet plug formation


3.Blood coagulation


*Hemostasis is controlled by positive feedback

Front (Term)

Back (Definition)

Fate of blood clots?

Back (Definition)

Thrombosis

Blood clot in a vessel supplying a vital organ (heart or brain)

Infarction

Death of tissues that have blocked blood vessels due to blood clot formation

Embolism

Blood clot that travels, and then blocks a blood vessel in in Organ (such as pulmonary embolism in lungs)

Atherosclerosis

Accumulation of fat in arterial linings can sometimes cause abnormal clot formation, a common form of thrombosis

For blood types


Type A,B,O, or AB

RBCs have antigens (ID tags)on their cell


Either A or B antigens or both


This determines your blood type

Antigen ID tags

Any molecule that evokes and immune response.


If immune system finds a foreign antigens in the body, it produces anti-bodies against the antigen

Anti-bodies

Proteins that react against a specific antigen.


In an incompatible blood transfusion, donor red blood cells RBCs evoke and immune response in the recipient, and anti-bodies in the recipients plasma agglutinate the donorsRBCs

Agglutination

Clumping of RBCs, which occurs when an anti-body in recipients plasma encounters its specific antigen on donors RBCs

Nothing

Nothing