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12 Cards in this Set
- Front
- Back
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dx criteria for diabetes |
-random glucose > 200mg/dl w/ classical s&s -fasting glucose > 126/dL -abnormal glucose tolerance test -glycated hemoglobin >= 6.5% |
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insulin is the most potent ________ hormone |
anabolic |
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DM 1 most commonly develops in |
childhood |
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environmental factors that may cause DM 1 |
viral infections |
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fundamental immune abnormality in DM 1 |
failure of self-tolerance in T cells |
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DM 1 morphology |
-v number and size of islets
-leukocytic infiltrates in islets made of T cells
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DM 2 morphology |
amyloid deposition and/or fibrosis w/in islets |
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hallmark of diabetic macrovascular disease |
accelerated atherosclerosis |
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most common cause of death w/ DM |
MI |
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3 lesions of diabetic nephropathy |
-glomerular lesions -renal vascular lesions -pyelonephritis, including necrotizing papillitis |
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glomerular lesions |
-capillary basement membrane thickening -diffuse mesangial sclerosis -nodular glomerulosclerosis aka kimmelstiel-wilson disease |
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w/ insulin deficiency there is catabolism of |
proteins and fats |
