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8 Cards in this Set
- Front
- Back
what are the treatment modalities for viruses
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treatment with antivirals
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what are the different types of antivirals?
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Neuramidase inhibitors
Acyclic Purinenucleoside analogs tricyclic amines |
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what ;are the mechanism of actions of antivirals?
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suppressing biochemical processes unique to viral reproduction
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HSV 1 causes most _____ infections
HSV 2 causes most ________ infections |
upstairs
downstairs |
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how does the herpes HSV-1 act?
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virus moves from point of infection, migrate down the senory neuron into the spinal cord, where lymphocytes can't in into. immunosuppressed state allows virus to re=emerge, Always reemerges at the point of infection. Viral shedding can occur even when no ulcers are apparent (this is why it's so contagious)
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are there many side effects from acyclovir?
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No, acyclovir only works in cells that are infected with Herpes, so it has very few side effects.
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what are the treatment modalities for influenza
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treat with anti virals that inhibit or virus replication, i.e. neuraminidase inhibitor
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Oseltamivir/Tamiflu and Zanmivir/Relenza both have what type of mechanism of action?
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neuraminidase inhibitor
(prophylactic action only, not a cure) both block neuraminidase on the surface of the influenza virus, (neuraminidase allows flue virus to bud off the infected cell) new virus cannot be released from an infected cell. Only prevents more virus from being shed. Only reduces duration by 24-36 hours. Both A and B, but must start within 2 days of symptoms. |