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22 Cards in this Set

  • Front
  • Back
What are the four stages of the cell cyle/
Mitosis, G2, S, G2
Which three stages constitute interphase?
G1, S, G2
What is the shortest stage of the cell cycle?
Mitosis
Where are the two checkpoints in the cell cycle?
G1, G2
What occurs in G1?
Everything except DNA is replicated
What occurs during S phase?
DNA synthesized
What do N and C refer to?
N = whether cell is haploid (1N) or diploid (2N)

C = number of chromatids (amount of DNA)
What is N and C for:

Diploid cell before copying its DNA
Diploid cell after copying its DNA
Haploid cell
Diploid before: 2N, 2C
Diploid after: 2N, 4C
Haploid: 1N, 1C
Describe the changes in N and C as a haploid cell undergoes meiosis.
Parent cell: 2N, 2C-->2N, 4C
2N, 4C-->1N, 2C
-->1N, 1C
What occurs during prophase?
Chromatin condenses into chromosomes
Centrosome complex forms MTOC; splits in two, head to opposite poles
Mitotic Spindle Formation
What occurs during prometaphase?
Nuclear envelope disrupted
Nucleolus disappears
Kinetochores assemble at each centromere on chromosomes

Kinetochore MT's and Astral MT's form
What occurs during Metaphase?
Chromosomes align at metaphase plate
What would be the effect of colchicine on a cell during metaphase?
Colchicine would inhibit microtubule formation and put cell under arrest
In what stage of the cell cycle are chromosomes used for karyotype analysis?
Metaphase: chromosomes are maximally condensed
What occurs during anaphase?
Kinetochores separate and chromosomes move to opposite poles
What occurs during telophase?
Chromosomes decondense, form chromatin

Nuclear envelope reforms
What occurs during cytokinesis?
Cytoplasm divides via cleavage
What cells make use of meiosis? What happens to N?
Germ cells: goes from 2N (46 chromosomes) to 1N (23 chromosomes)
How many rounds of DNA synthesis and division occur during meiosis?

What's the difference between Meiosis I and Meiosis II?
One round of DNA synthesis followed by two rounds of segregation and cell division

MI: homologous chromosomes segregate to daughter cells
MII: chromatids from each chromosome segregate to daughter cells

Forms four haploid cells
What are the 4 subdivisions of prophase I of meiosis? What occurs in each?
Leptotene:
Chromosomes already replicated
Condensation begins

Zygotene:
Synapsis: homologous chromosomes pair closely; held together by synaptonemal complex

Pachytene:
Condensation of chromosomes continues
Synapsis complete: each pair of homologs appear as bivalents (tetrads)
CROSSING OVER TAKES PLACE

Diplotene:
Synaptonemal complex disappears; two components of tetrad (bivalent) separate
Centromere of each homolog intact; chromatids held at chiasmata (location of crossover)
In what subdivision of prophase does crossing over occur?
PACHYTENE
What's the name of the region where on a chromosome where crossing over occurs?
Chiasmata