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32 Cards in this Set
- Front
- Back
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DOC for strep throat |
penicillin |
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most common bacteria from the head to neck |
-step pneumo -H. flue -Moraxella catarrhalis |
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doc for acute bacterial rhinosinusitus |
amox-clavulanate |
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DOC for astma |
glucocorticoids |
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Inhaled corticosteroids (ICS) I: and AE |
I: persistent asthma (prevent acute attacks) AE: thrush and dysphonia (deepening and horsening of voice) |
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B2 agonists I: |
-Asthma- intermittent (prn), DOC for exercise induced Adjunct -COPD- sx relief (prn) -SABA- short acting B2 agonists -LABA-Long-acting B2 agonist- NOT FOR RESCUE |
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B2 AE |
tachcardia, muscle tremor, anxiety NEVER USE LABA BY ITSELF! |
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1st line for COPD |
anticholinergics |
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anticholinergics |
-muscarinic receptor antag -block parasympathetic I: COPD- sx relief, exacerbations asthma- only in ED management |
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anticholinergic AE |
dry mouth, pharyngeal irritation |
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Leukotriene modifiers |
-not as effective as corticosteroids I: persistent asthma |
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Theophylline |
-related to caffeine I: end stage COPD |
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Theophylline AE, DI |
AE- nause, CNS stimulation, tahcycardia tox-> arrhythmias, seizure, death DI- cyp, CIGARETTE SMOKING not used often |
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only intervention in COPD that increases survival |
O2
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DOC for Bordetella pertussis |
macrolide (azithromycin, clarithromycin) |
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Need 2/3 to consider antibiotics for chronic bronchitis |
increased sputum volume increased purulence SOB |
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Pneumocystis jirovecii pneumonia |
-most common life threatening opportunistic infection w/ AIDs -Trimethoprim-sulfamethoxazole DOC -fungus w/ protozoan characteristics |
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Isoniazid (INH) MOA |
-prodrug- requires activation by mycobacterial catalase-peroxidase (KatG) -mycolic acid responsible for acid-fast staining |
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rifampin (RIF) |
-broad spectrum I: 1st line agent in combo therapy for LTB and ATB can be used for leprosy never used alone |
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rifampin AE & DI |
AE: (all do hepatitis), red-brown saliva, tears and urine DI: INDUCER of CYP |
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Rifapentine (RPT) |
Longer half life than rifampin once a week dosing |
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rifapentine I: |
-combo w/ INH-RPT weekly for 3mo for LTB |
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Pyrazinamide (PZA) |
I: no cross-resistance w/ other anti-tb drugs -1st line w/ combo in intensive phase -important for continuation phase for MDR-TB |
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pyrazinamide AE |
Hyperuricemia (interaction w/ gout) |
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ethambutol (EMB) |
-bacteriostatic AE- Optic neuritis, decrease visual acuity, impaired red-green color discrimination |
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Amikacin |
recommended IV agent for combo for MDR-TB |
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Rifabutin |
-One use: HIV pts w/ tb |
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Intensive phase tb tx |
isoniazid rifampin pyrazinamide ethambutol |
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continuation phase tb tx |
isoniazid rifampin |
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PPD 5mm + |
HIV
recent contact of active TB transplant pt immunosuppressed |
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PPD 10mm + |
-foreign born from high tb regions -IV drug abuser -lab or health personnel children < 5 |
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PPD 15mm + |
all |
