Block 2 Path Exam -- Vascular Disease Lecture

Front 1

Atherosclerosis

Back 1

Affects large and medium sized arteries
Results in formation of atheromas

Front 2

Causes of DVT

Back 2

Stasis
Injury (trauma)
Hypercoagulant state

Front 3

Intimal cell masses

Back 3

Accumulation of smooth muscle cells in the normal intima
Found in infants at sites where atherosclerosis occurs in adults

Front 4

Large Elastic Arteries

Back 4

Tunica intima -- endothelium and connective tissue
Tunica media -- smooth muscle cells, intervening elastic fibers
Adventitia -- connective tissue, blood vessels, and nerves
Adventitia

Front 5

Large Muscular Arteries

Back 5

Layers same as elastic, BUT, the tunica media has an internal elastic lamina, smooth muscle, and an external elastic lamina

Front 6

Monckeberg Medial Sclerosis

Back 6

Affects large and medium sized muscular arteries
Degenerative calcification of the media

Usually in upper and lower extremities of old people

Front 7

Syphilitic Aneurysm

Back 7

Occur in the ascending aorta
Shape is fusiform
Inflammation surrounding the vasa vasorum causes medial scarring

Front 8

Arteriosclerosis

Back 8

Affects smaller arteries and arterioles
Results in hyaline thickening of vessel wall

Front 9

Atherosclerotic Aneurysm

Back 9

Most common in the distal aorta and common iliac arteries
Shape is fusiform or saccular
More common in hypertensives

Front 10

Dissecting Aneurysm

Back 10

Most common in the proximal aorta
Dissection is between the inner two thirds and outer third
Most common complication is hemorrhage

Front 11

Hemangioma

Back 11

Benign
Capillary --> birthmark
Cavernous --> port wine stains

Front 12

Angiosarcoma

Back 12

Rare, malignant neoplasm of endothelial cells
Most commonly in skin and soft tissue
Of liver, associated with arsenic and vinyl chloride

Front 13

Kaposi Sarcoma

Back 13

Malignant endothelial tumor
Seen frequently in AIDS patients
Commonly occurs on skin, mucosal membranes, GI tract, and lungs
Evidence implicates Human Herpesvirus 8