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12 Cards in this Set
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Appearance of endometrium on Oral contraceptives
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Small, inactive glands
Pre-decidualized stroma (progesterone effect) |
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Acute Endometritis
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Usually result of bacteria (Staph, Strep, N. Gonnorrhoeae)
Usually occurs in postpartum or postabortal period Fever, chills, pelvic pain Histology -- focal aggregates of PMNs in stroma and filling gland lumens |
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Chronic Endometritis
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Non-specific, but probably due to infections or trauma
Histology -- infiltrate of PLASMA CELLS and lymphocytes |
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Endometrial Polyps
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BENIGN
Contain cystically dilated glands, fibrotic stroma THICK-WALLED blood vessels |
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Adenomyosis
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Endometrial glands and stroma within the myometrium
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Endometrial hyperplasia
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Most commonly in perimenopausal women
If cytologic atypia is present --> increased risk of cancer |
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2 types of Endometrial Adenocarcinoma
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Endometrioid (most common)
Uterine Papillary Serous Carcinoma (UPSC) |
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Endometrioid Carcinoma
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Excessive estrogen is the main association
75% of patients are POST-menopausal (~63 yo) 75% of patients present with stage I disease (90% 5 yr.) Potentially curable if detected early enough |
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Uterine Papillary Serous Carcinoma (UPSC)
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Tends to occur in elderly women
Occurs in setting of atrophy, NOT hyperplasia Tends to present at higher stages Aggressive, has a poor prognosis |
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Leiomyoma
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Most common neoplasm in women (~25% pre-menopausal)
BENIGN, but can get extremely large Gross -- well-circumscribed, spherical, dense, whorled, tan-white Histology -- interlacing bundles of UNIFORM cells |
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Leiomyosarcoma
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Rare and malignant
Often metastasize within 2 yrs. of diagnosis (lung, liver, brain) Gross -- similar to leiomyoma, BUT hemorrhage and necrosis Histology -- cytologic atypia, mitotic activity, necrosis |
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Malignant Mixed Mullerian Tumor (MMMT)
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Aggressive tumor with a poor prognosis (30% 5-yr.)
Often presents at high stage Histology -- mix of adenocarcinoma and malignant mesenchymal components Characteristic presentation: Elderly woman, polypoid endometrial mass protruding through cervix |