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15 Cards in this Set

  • Front
  • Back
Seborrheic Keratosis
BENIGN
Common
Sharply demarcated tan tumor elevated above adjacent normal skin
"Stuck on" appearance
Papillomatosus or plaque-like proliferation of mature epidermal cells
BOTH basaloid and squamoid features
Removed for cosmetic purposes
Skin Tag
BENIGN
Small, soft, flesh-colored papillary/polypoid lesions
Often multiple
Core of collagen covered by seborrheic keratosis-like epidermis
A.K.A. fibroepithelial polyps, acrochordons
Epidermal Cyst
BENIGN
Cystic dilatation of follicular infundibulum
Lined by epidermis, filled with keratin
A.K.A. wen and sebaceous cyst
Keratocanthoma
BENIGN
Relatively common
Grows rapidly
Elevated, dome-shaped nodule with central keratin crater
Growth stops after few weeks, and then involutes
Leaves a scar
Histo -- cup-shaped tumor
Adnexal Tumors
BENIGN
Syringoma -- tumor of eccrine sweat glands
(occurs as small, infraorbital papules)
Trichoepithelioma -- shows follicular differentiation

Most of these are treated by simple excision
Actinic Keratosis
PRE-MALIGNANT
Small, scaly papules or patches
Develop on sun-exposed surfaces
Middle-aged - Elderly fair-skinned individuals
MOST SCC ARISE FROM THESE
Thickened keratin layer, occasionally an elevated cutaneous horn
Solar Elastosis -- evidence of sun damage
Bowen's Disease
SCC in Situ of the skin
Well-defined scaly plaque ANYWHERE
Histo -- full thickness epidermal atypia
Most of the time can be excised
5% can give rise to invasive SCC
Once invasive, met rate is as high as 40%
Can develop in chronic arsenic exposure, or from HPV
SCC
Majority of these arise in actinic keratoses
Only rarely metastasize
BUT, SCCs that develop de novo have met potential of 10-40%
Atypical, eosinophilic, squamoid epithelium
Basal CC
Most common malignant skin tumor
Usually middle-aged people on sun-exposed areas
BUT, can in youth at non-exposed sites
Hallmark is pearly, translucent papule or nodule
Telangiectasia
GROWS RELENTLESSLY if not excised
Metastasis is uncommon
Sclerosing (Morpheaform) BCC
Scar-like lesion
Small tumor islands embedded in fibrotic stroma
Borders are often difficult to define --> incomplete excisions, recurrence
Dermatofibroma
Firm, immobile intradermal nodule
Usually found on extremities of young or middle-aged adults
Localized proliferation of fibroblasts and histiocytes
Easily treated by local excision
Infantile Capillary Hemangioma
A.K.A strawberry hemangioma
Presents at birth
Flesh-colored, variable size
Becomes red or purple
Disappear by mid-childhood
Histo -- sheets of closely packed capillaries form large nodules
Lobular Capillary Hemangioma
A.K.A. pyogenic hemangioma
Rapidly evolving, pedunculated, red-purple tumor
Occurs on skin or mucous membranes
BLEEDS EASILY
Lobular arrangement of capillaries
Sometimes recur with incomplete excision
Kaposi's Sarcoma
Most often seen in AIDS patients
ASSOCIATION WITH HERPES VIRUS 8
Red to purple papules and patches
Erythrocytes occupy narrow slits between spindle cells
In elderly people, managed by local irradiation or excision
Paradoxically, AIDS patients have longer survival with this
Mycosis Fungoides
Most common primary cutaneous lymphoma (T CELL)
Ultimately disseminates to lymph nodes and viscera --> FATAL
Early on, resembles dermatitis
Infiltrated plaques develop: band-like infiltrate in superficial dermis
Markedly folded nuclear contours
Pautrier microabscesses (intreepidermal)
As cutaneous tumors develop, prognosis is extremely poor
Death within 6 - 18 months