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15 Cards in this Set
- Front
- Back
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Seborrheic Keratosis
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BENIGN
Common Sharply demarcated tan tumor elevated above adjacent normal skin "Stuck on" appearance Papillomatosus or plaque-like proliferation of mature epidermal cells BOTH basaloid and squamoid features Removed for cosmetic purposes |
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Skin Tag
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BENIGN
Small, soft, flesh-colored papillary/polypoid lesions Often multiple Core of collagen covered by seborrheic keratosis-like epidermis A.K.A. fibroepithelial polyps, acrochordons |
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Epidermal Cyst
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BENIGN
Cystic dilatation of follicular infundibulum Lined by epidermis, filled with keratin A.K.A. wen and sebaceous cyst |
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Keratocanthoma
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BENIGN
Relatively common Grows rapidly Elevated, dome-shaped nodule with central keratin crater Growth stops after few weeks, and then involutes Leaves a scar Histo -- cup-shaped tumor |
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Adnexal Tumors
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BENIGN
Syringoma -- tumor of eccrine sweat glands (occurs as small, infraorbital papules) Trichoepithelioma -- shows follicular differentiation Most of these are treated by simple excision |
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Actinic Keratosis
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PRE-MALIGNANT
Small, scaly papules or patches Develop on sun-exposed surfaces Middle-aged - Elderly fair-skinned individuals MOST SCC ARISE FROM THESE Thickened keratin layer, occasionally an elevated cutaneous horn Solar Elastosis -- evidence of sun damage |
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Bowen's Disease
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SCC in Situ of the skin
Well-defined scaly plaque ANYWHERE Histo -- full thickness epidermal atypia Most of the time can be excised 5% can give rise to invasive SCC Once invasive, met rate is as high as 40% Can develop in chronic arsenic exposure, or from HPV |
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SCC
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Majority of these arise in actinic keratoses
Only rarely metastasize BUT, SCCs that develop de novo have met potential of 10-40% Atypical, eosinophilic, squamoid epithelium |
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Basal CC
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Most common malignant skin tumor
Usually middle-aged people on sun-exposed areas BUT, can in youth at non-exposed sites Hallmark is pearly, translucent papule or nodule Telangiectasia GROWS RELENTLESSLY if not excised Metastasis is uncommon |
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Sclerosing (Morpheaform) BCC
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Scar-like lesion
Small tumor islands embedded in fibrotic stroma Borders are often difficult to define --> incomplete excisions, recurrence |
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Dermatofibroma
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Firm, immobile intradermal nodule
Usually found on extremities of young or middle-aged adults Localized proliferation of fibroblasts and histiocytes Easily treated by local excision |
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Infantile Capillary Hemangioma
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A.K.A strawberry hemangioma
Presents at birth Flesh-colored, variable size Becomes red or purple Disappear by mid-childhood Histo -- sheets of closely packed capillaries form large nodules |
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Lobular Capillary Hemangioma
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A.K.A. pyogenic hemangioma
Rapidly evolving, pedunculated, red-purple tumor Occurs on skin or mucous membranes BLEEDS EASILY Lobular arrangement of capillaries Sometimes recur with incomplete excision |
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Kaposi's Sarcoma
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Most often seen in AIDS patients
ASSOCIATION WITH HERPES VIRUS 8 Red to purple papules and patches Erythrocytes occupy narrow slits between spindle cells In elderly people, managed by local irradiation or excision Paradoxically, AIDS patients have longer survival with this |
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Mycosis Fungoides
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Most common primary cutaneous lymphoma (T CELL)
Ultimately disseminates to lymph nodes and viscera --> FATAL Early on, resembles dermatitis Infiltrated plaques develop: band-like infiltrate in superficial dermis Markedly folded nuclear contours Pautrier microabscesses (intreepidermal) As cutaneous tumors develop, prognosis is extremely poor Death within 6 - 18 months |
