Block 2 Muscle Tissue

Front 1

cell structure of muscle tissue from smallest to largest

Back 1

myofibril<myofiber<fasicle<multiple fasciles<gross muscle (bicep)

Front 2

in embryo, ____fuse together to form extremely large muscle _____ which is _____

Back 2

myoblasts fuse together to form extremely large muscle fiber, which is multinucleate.

cells that remain in reserve for tissue replacement=satelllite cells

Front 3

endomyosin wraps around what?

Back 3

bundle of muscle fibers

Front 4

perimyosin is in between what?

Back 4

inbetween different groups/bundles of muscle fibers that are wrapped up by endomyosin

Front 5

epimyosin wraps around what?

Back 5

wraps around peri and endomyosin and muscle fibers

Front 6

Z disc to Z disc= what?

Back 6

a sarcomere

Front 7

M line is where in the sarcomere?

Back 7

the middle! M for middle.

Front 8

how to remember H zone, M line, A band?

Back 8

M, H, A. My Hot Ass. Small-large

Front 9

I band. how much of it is in the sarcomere?

Back 9

1/2 on each side

Front 10

A band vs. I band

Back 10

A band=thick filaments (A is thicker letter)
I band=thin filaments (I is thin letter)

Front 11

titin is a molecule that extends from ___ to ____

Back 11

from the Z disk to the M line and is anchored at both end.

Front 12

nebulin is a ______filamentous protein that does what?

Back 12

non-contractile protein that keeps the actin filaments in line and regulates their length

Front 13

what is the role of desmin?

Back 13

intermediate filament that keeps myofibrils together and to the sacrolemma

plectin assembles desmin filaments into network btw myofibrils

Front 14

what shortens during contraction?

Back 14

the H zone

Front 15

muscular dystrophies are cause by a defect in.....

Back 15

dystrophin=weakinging/loss of link btw cytoskelton and ECM-->>>disarray of myosin and actin filaments=myofiber degeneration

Front 16

myocyte=?
myofibril=?

Back 16

muscle cell (smallest)
-had to stop

Front 17

during contraction, what band/zone disappears

Back 17

I band disappears

Front 18

how to remember parts of the sarcomere

Back 18

from the middle: MHAIZI

"AI Band" Artificial Intelligence Band

"A" is thicker than "I"

Front 19

what makes up a triad?

Back 19

one T-tubule and 2 terminal cisternaue of sarcoplasmic reticulum
in skeletal muscle, located at the junc of the A and I band=2 triads per each sarcomere

Front 20

______magnify the influence of one stimulus by forming a NMJ with more than one myofiber.

used in what kind of muscles?

Back 20

collaterals

postural muscles which require multiple recruitments to maintain upright posture

Front 21

how to remember extrafusal vs. intrafusal?

Back 21

extrafusal fibers do "extra" work, actually DO the work of contracting muscle spindles

intrafusal fibers "fuse/look within themselves, to monitor the level of their contraction/load bearing" they are all zen-like with their gamma fibers. (proprioceptors)

Front 22

what are the 2 types of intrafusal fibers?

Back 22

nuclear bag fiber

nuclear chain fiber

Front 23

myosin vs. actin. which is thick and which is thin?

Back 23

ac-"thin" vs. MY-you have thick filaments-osin

Front 24

smooth muscle. cells are what shaped?

use the same binding protein that make up Z-discs, called what?

what is functional syncytium?

Back 24

fusiform, not a sarcomeric pattern

alpha-actinin

smooth muscle behaves like one cell. gap junctions btw cells conduct AP, adhering junctions integrate force across all cells=function syncytium

Front 25

how does calcium get inside the smooth muscle cell?

Back 25

caveolae form from surface lipid rafts-invagination/endocytosis brings in Calcium. spread via gap junctions

Front 26

in smooth muscle, what are the plasma membrane dense bodies?

Back 26

the "Z discs" of smooth muscle. the actin-myosin budnles radiate from the dense bodies which are usually anchored into the membr of the smooth muscle cell. made of alpha-actinin

Front 27

smooth muscle cells do not have a ____

smooth muscle innervation

Back 27

no NMJ! influenced by autonomic nervrous system. an release componaent than can enhance or suppress contract

contractile ability of Smooth muscle cell is not innervated!

ability to contract is an inherent ability of the smooth muscle itself

Front 28

calmodulin sequence and caveolae important in what?

Back 28

smooth muscle contraction. endocytosis. research more about this!