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6 Cards in this Set

  • Front
  • Back
Following endothelial injury, what are the 2 main functions of platelets?
1) Formation of a platelet plug
2) Provide a phospholipids surface for the reactions of the coagulation cascade
What is PDGF (Platelet Derived Growth Factor)?
GF produced by platelets (in alpha granules) which stimulates the action of vascular smooth muscle cells in the healing process
Platelets are responsible for 1° or 2° hemostasis?
Primary hemostasis
How do platelets adhere to the subendothelial collagen?
Through binding to VWF
True or false: platelet abnormalities will cause changes in PT and PTT abnormalities?
False
Platelet phospholipid surface is required for which 2 steps of the coagulation cascade?
10 → 10a
Prothrombin → Thrombin