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3 Cards in this Set
- Front
- Back
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CBC:
Hb 84 g/L (decreased) MCV 101 fL (increased) Hct 0.298 (decreased) RDW 16.0 (increased) WBCs normal Platelets normal |
Interpretation:
Macrocytic anemia with anisocytosis |
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Total bilirubin 45 umol/L (increased)
LDH 853 IU/L (increased) |
Interpretation:
Increased indirect (unconjugated) bilirubin and LDH indicates hemolytic anemia (RBC lysis/increased destruction of RBC's) |
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Reticulocyte count (increased)
Coombs' test: Positive (IgG) Peripheral smear: Marked polychromasia, many spherocytes |
Interpretation:
Increased retic count means the bone marrow response to blood loss is normal. Positive Coombs' test means that patient's RBCs have antibodies and/or complement bound to them; RBC's are cross-linked by multivalent Abs and this causes clumping. Marked polychromaisa shows increased retics present (nuclear material is polychromatic) and many spherocytes indicates that RBC's are spherical, less pliable b/c of splenic phagocytosis; part of RBC membrance is lost. Normal shape is biconcave disc. |
