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23 Cards in this Set

  • Front
  • Back
What is the difference between blood and plasma?
Blood = Cells + plasma

Plasma = Water, protein, and solutes.
What is a reticulocyte?
new RBC’s from bone marrow – complete hemogobin synthesis & mature 1-2 days after entering circulation
RBC proliferation is up-regulated by kidney hormone...?
erythropoietin
this WBC has 3 lobes and is the first phagocytic cell to appear during bacterial inflammation
Neutrophil

note: They roll across the endothelium until they leave the blood and become actively phagocytic.
this WBC has a lobulated nucleus and has granules with hydrolytic enzymes, histamine, heparan sulfate proteoglycan, & slow reacting substance.
Basophil
This WBC is used to fight parasitic infections and contains granuales with lysosomal enzymes and major basic protein, MBP
Eosinophils

note: MBP is an anti-parasitic agent
Phagocytic leukocyte with a oval or kidney bean-shaped nucleus

important in regulation of immune response and inflammation

what WBC?
Monocyte
Nucleus is round/oval in small/medium lymphocytes & may be more reniform in large lymphocytes. Very little cytoplasm evident. They ARE NOT phagocytic
Lymphocytes
Memory cells and plasma cells are what type of lymphocytes
B-lymphocytes

note:

T-lymphocytes: mature in thymus.
Killer T cells: involved in graft and transplant rejection. Their normal role is to lyse virus-infected cells displaying viral antigens.
Helper T cells: enhance B and T lymphocyte activity
Suppressor T cells: suppress B and T lymphocyte activity
Why is adult bone marrow less hematopoietic than in fetal development?
because it regresses from hematopoietic red marrow to fat-storing yellow marrow

note: Adult red marrow
is found in vertebral
bodies, ribs, sternum,
iliac bones, proximal
humerus and
proximal tibia.
what type of arteries are found in the Aorta, pulmonary, common carotids, subclavians, & common iliac arteries?
Elastic
these blood vessels have a single endothelial layer surrounded by thin sheath of reticular & collagenous fibers & some pericytes.
Capillary
These blood vessels have several smooth muscle layers between the endothelial lining of the lumen and the adventitia
Arterioles
what type of capillaries are found in the GI tract, endocrine glands, renal glomerular tubules (no basal lamina), choroid plexus, & ciliary body
Fenestrated
what type of capillares are found in the liver and hemopoietic organs (spleen, bone marrow)?
Sinusoidal
What are the 2 "pulps" in the spleen and their basic functions?
White:
--made of B&T lymphocyte cell islands; surrounds and follows arteries

Red:
--Removal of old and damaged RBCs
--iron is released and transported to the marrow for new RBCs
What do direct and indirect blood levels of bilirubin tell you? what if they are elevated (what type of things could be going on)?

**
Direct = conjugated bilirubin (↑ in bile duct blockage, cirrhosis, hepatitis since conjugated bilirubin cannot exit the liver in the normal manner through the duodenum.)

Indirect = unconjugated bilirubin (↑ in anemias, other blood disorders. The liver is operating normally but the spleen is overwhelming it with too much unconjugated bilirubin due to excessive breakdown of RBC’s)
fluid passing through lymph nodes is exposed to what 2 things?
B & T lymphocytes
Starting at the cisterna chyle, navigate the lymphatics to the appropriate subclavian vein
Lymph from both lower limbs and the abdominopelvic viscera collects in a large sac (sometimes multiple sacs) called the --cisterna chyle--

From the cisterna chyle, the lymph flows up the --thoracic duct-- to reach the left subclavian vein.

Lymph from the left upper limb and left head & neck also drains to the --left subclavian vein--.

Lymph from the right upper limb and right head & neck drains to the --right subclavian vein--.
a nontender, firm, enlarged lymph node would indicate what?
Metastatic lymphnode
most lymphatic flow from the breast travels to what node?

**
Axillary lymph node
If lymph flow, or metastisis were to cross from one breast to another, what node would it have to cross?
parasternal
He had like 5 straight slides of lymphatic drainage...feel free to look at them if you want but I am not. And those were the final slides.
Donezo