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4 Cards in this Set

  • Front
  • Back
What does antisense nucleotides do?
they hybridize to the disease producing mRNAs thus interfere w/ translation and pathology of disease
Advantage of antisense therapy?
highly specific, and complementary due to hydrogen bonding
Problems associated w/ antisense therapy?
delivery of oligo to the infected cell and identification of the specific replication or growth of cancer cells
What antisense drug is used to inhibbit CMV?
Formivirsen 21 mer phosphorothioate oligodeoxynucleotide