Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
4 Cards in this Set
- Front
- Back
What does antisense nucleotides do?
|
they hybridize to the disease producing mRNAs thus interfere w/ translation and pathology of disease
|
|
Advantage of antisense therapy?
|
highly specific, and complementary due to hydrogen bonding
|
|
Problems associated w/ antisense therapy?
|
delivery of oligo to the infected cell and identification of the specific replication or growth of cancer cells
|
|
What antisense drug is used to inhibbit CMV?
|
Formivirsen 21 mer phosphorothioate oligodeoxynucleotide
|