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69 Cards in this Set
- Front
- Back
What are the 3 functional units of brain organization?
Who came up with them? What do they regulate? |
First Functional Unit
Second Functional Unit Third Functional Unit Luria They regulate sleep/waking |
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What is the First Functional Unit
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Structures that regulate/maintain optimal cortical tone (sleep/waking processes, levels of arousal, attention)
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What is the 2nd Functional Unit of Luria's for sleep/waking?
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Structures & processes assoc w/acquisition & retention of info (sensation, perception, memory)
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What is the 3rd Functional Unit of Luria's for sleep/waking?
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Structures & processes assoc w/initiation, regulation, & verification of Bx
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Which is NOT true about sleep:
a. fluctuates in activity, brain/body interactions b. is an active process c. is taken for granted d. stops once you are awake |
d. fundamental sleep/arousal systems are involved in all waking processes. Arousal underlies all aspects of brain and psych functioning
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What is Optimal Cortical Tone
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a person's ideal degree of alertness for a given task
Described by Luria First functional unit |
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Which of the below is (are) true about normal sleep?
a. Sleep should be btwn 6-13 hrs b. SOL is <30 c. Sleep is subjectively satisfying d. Sleep architecture stays the same across the lifespan e. abc f. all of the above |
e. Sleep architecture changes across the niht & across the course of development & maturation
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What is Sleep Onset Latency?
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the average amount of time it takes someone to fall asleep on most nights. It is less than 30 min
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What does the sleep state represent?
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A great effort by the nervous system, metabolism, and synchrony.
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What is one of the vegetative signs of most of the major Axis I & II pathologies?
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Sleep disturbances
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What is the easiest measure of sleep quality?
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EEG
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How many stages of NON-REM sleep are there?
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4
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What occurs during NREM Stage I?
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5 minutes long
The brains decision to progress to deeper sleep; ends w/complete disconnection of sensory awareness |
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What occurs during NREM Stage II?
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subjective sleep; brain's effort to establish & maintain sleep
EEG shows Phasic Phenomena - assoc w/either no mental activity or incomplete, disjointed mentations |
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What occurs during NREM Stage III?
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Beginning of deep, slow wave sleep. Proportional to the amount of physical effort exerted during the day.
- part of deep electrographic sleep -assoc w/no or minimal mental activity |
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Describe Stage IV of NREM?
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deep, slow wave sleep
-like Stage III it is proportional to daily physical activity & assoc w/no mental activity |
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What is an Epoch of EEG?
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30sec; a unit of time of EEG activity
-based on time for paper to pass 1 page of EEG paper |
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What are alpha waves?
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predominantly from occipital lobe; state of relaxation.
-can be experienced by advanced meditators when they are meditating - REM sleep |
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What are theta waves? What sleep stages do you see these in?
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>50% - Stage 1 NREM
>50% & no alpha - Stage II Some in Stage III |
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What is a K Complex?
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Stage II sleep; part of phasic phenomena
consistent clusters of activity in EEG |
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What are sleep spindles? What phase do they appear in?
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Stage II w/k complexes
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What is the Phasic Phenomena?
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Sleep spindles & k-complexes
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What is the difference between NREM stage 1 & 2 and 3&4?
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3&4 are restorative because they have more delta (big slow waves)
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What is the EEG montage?
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The array of electrodes on the scalp.
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Describe Stage IV of NREM?
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deep, slow wave sleep
-like Stage III it is proportional to daily physical activity & assoc w/no mental activity |
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What does the EEG tell you about sleep?
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car exhaust. It is vague but reps some function of cortical & subcortical activity
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What are theta waves? What sleep stages do you see these in?
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>50% - Stage 1 NREM
>50% & no alpha - Stage II Some in Stage III |
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Describe Stage IV of NREM?
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deep, slow wave sleep
-like Stage III it is proportional to daily physical activity & assoc w/no mental activity |
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What are sleep spindles? What phase do they appear in?
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Stage II w/k complexes
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What is the Phasic Phenomena?
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Sleep spindles & k-complexes
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What is the difference between NREM stage 1 & 2 and 3&4?
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3&4 are restorative because they have more delta (big slow waves)
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What are theta waves? What sleep stages do you see these in?
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>50% - Stage 1 NREM
>50% & no alpha - Stage II Some in Stage III |
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Which stages of sleep are associated with various parasomnias?
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Stages of III & IV NREM
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On an EEG, what does Stage IV sleep pattern resemble?
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a coma
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What do a lot of PGO spikes and Saw Tooth Waves show?
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Dreaming during REM sleep
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What does Emergent Stage I REM sleep look like on EEG?
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alpha and beta activity w/saw-tooth waves and PGO spikes
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How long are REM episodes? Do they change?
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They change throughout the night; start at 5 minutes and end at 20 minutes.
Occur in 90 min intervals |
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What does REM sleep reflect?
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-amount of cognitive activity from the day
-exposure to new kinds of info -memory processes (consolidation & removal of old stuff) -protein synthesis & synaptogenesis |
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What is a REM Intrusion?
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an indication of sleep deprivation
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What part of the brain is off during REM sleep?
What might this explain? |
prefrontal cortex (volition, morality, intention, etc)
-may explain why dreams are disorg & illogical |
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Motor activity during EEG REP sleep - is it possible?
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Yes but it may reflect a pathological (or abnormal) condition
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What is REM rebound?
How do we usually interpret them? |
a mini-withdrawal; shows you can experience w/drawal from a REM blocker after one dose (such as alcohol)
-features inc'd length & freq of REM episodes -usually interpreted as a nightmare |
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Who gets more REM - an infant or a teenager?
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Infant (especially 3 &4)
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What are the greatest enemies of sleep?
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Age (starting at 25, then 45, then 65)
Sleep Deprivation Drugs Pain/Illness Lifestyle |
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At what ages are parasomnias considered more normal?
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3 & 4
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What are the biological mechanisms behind sleep?
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Ascending Reticular Activating System (ARAS)
and 5HT, ACh, and GABA |
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What is the ARAS?
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Ascending Reticular Activating Systems
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What is the MRF?
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Mesencephalic Reticular Formation; Source of arousal
Connected with the Locus Coeruleus |
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What is the LC?
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Locus Coeruleus; source of NEPI norepinephrine
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What is the order of the ARAS?
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brain arousal = MRF-->LC-->DTS --> cortex-->anterior cortex -->MyRF-->RN-->MRF
Body arousal = MRF --> LC-->PH-->adrenals |
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What is the DTS?
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crossroads of everything in the brain; sends stimulation to everything in the cortex
-Diffuse Thalamic System aka Intrinsic thalamic nuclei |
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How do you wake up?
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Diffuse Thalamic System sends out excitation to all of the cortex
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Anterior Cortex (cingulate gyrus, frontal lobesk, basal forebrain)
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-monitors level of arousal
-if you wake up & feel wide awake, this sends message to posterior MRF (myelencephalic reticular formation) |
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Raphe Nucleus
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source of serotonin in the brain
- gets a signal from posterior MRF and this either inhibits or dishibits the MRF to wake you up |
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The Locus Coeruleus activates the posterior hypothalamus in ARAS- what does this accomplish?
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Adrenaline and the wakening of your body
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What happens during sleep paralysis?
Sleep walking? |
ARAS activated your DTS but not the posterior hypothalamus
The reverse |
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What are the types of apneas?
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Obstructive
Central Mixed Cheyne-Stokes SID (Hering-Breuer reflex) |
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What is nocturnal myoclonus?
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-actual movement while falling asleep (commonly kicking)
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What is one cause for ADD diagnosis?
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A kid w/apnea - doesn't get sleep
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What neurochemical keeps the cortex under inhibitory control during NREM sleep?
a. 5HT b. GABA c. ACh d. None of the above |
a.
5HT inhibits the NEPI system to maintain slow wave sleep in NREM |
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Which chemical reduces inhibition to cortex and marks onset of REM sleep? This one also marks the end of REM sleep to bring back a slow wave pattern.
a. GABA b. Serotonin c. Adrenalin d. Acetylcholine |
d. ACh
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What takes over to maintain sleep state in the cortex during REM?
a. 5HT b. GABA c. ACh d. GABA blockers |
b. after ACh has reduced inhibition of 5HT in the cortex, GABA takes over
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What neurochemical appears to be necessary for REM phenomena (saw tooth waves & PGO Spikes) and conscious dreams?
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GABA
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What blocks conscious dreams, PGO Spikes, saw tooth waves, and REM?
a. GABA b. ACh c. GABA blockers d. Adrenalin |
c. gaba blockers
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Which type of insomnia are anxiety disorders linked with?
a. onset b. maintenance c. early morning waking d. obstructive |
a. onset
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Which type of insomnia are ruminative/worry disorders linked with?
a. onset b. maintenance c. early morning waking d. mixed |
maintenance, b
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Which type of insomnia are depressive disorders linked with?
a. onset b. maintenance c. early morning waking d. central |
early morning waking, c
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__a____ time sets the clock better than ___b___ time in circadian rhythm disorders
options: sleeping, waking, bed |
a- waking
b- sleeping |
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What is the one medication that can induce natural sleep?
a. Valerian b. diphenhydramine c. Luminal d. Rozerem |
d. stimulates melatonin receptors, which triggers natural sleep process w/almost no side effects, slow development of tolerance, and little/no dependence
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