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35 Cards in this Set

  • Front
  • Back
Respiratory impairment during systemic anaphylaxis is PRIMARILY due to

arteriole dilation.
reduced blood pressure.
increased capillary permeability.
circulatory shock.
smooth muscle contraction in the bronchioles.
smooth muscle contraction in the bronchioles
Cytokines attract which of the following to the affected tissue?
Lymphocytes
Macrophages
Basophils
All of the above
None of the above
All of the above
A "foreign" molecule which can invoke the immune response is called a(n)

immunoglobulin.
colony-stimulating factor.
hapten.
antigen.
antibody.
antigen.
This type of antibody binds to mast cells and basophils, thus invoking inflammation. They are secreted by plasma cells of the mucosae



IgM
IgA
IgG
IgE
IgD
IgE
Which cells stimulate both arms of the immune response? Without these cells there is no immune response.

Complement cells
Basophils
Helper T-cells
Plasma cells
Killer T-cells
Helper T-cells
Which of the following is the hallmark of the humoral immune response?

Phagocytosis
Cell lysis by T cells
Interferon production
Binding of antibody to the antigen.
Antigen presentation
Binding of antibody to the antigen
All of the following are examples of characteristics of adaptive defenses EXCEPT

they are specific.
They are usually initiated in a lymph node.
they are systemic.
they have memory.
we are born with them.
we are born with them.
All of the following are examples of autoimmune disorders EXCEPT

systemic lupus erythematosus (SLE)
Grave's disease.
rheumatoid arthritis.
sickle cell anemia.
Myasthenia gravis
sickle cell anemia
The process that begins when a helper T-cell binds to an MHC class II protein on a displaying cell is known as

antigen proliferation.
costimulation.
T-cell proliferation.
self antigen recognition
costimulation.
Which of the following is NOT one of the cardinal signs of inflammation?

Opsonization
Heat
Pain
Swelling
Redness
Opsonization
Which cells of the innate immune response are responsible for detecting and destroying parasites?

Mast cells
Neutrophils
Eosinophils
Natural killer cells
Natural killer cells
Which of the following is NOT a surface barrier to pathogen influx?

Complement cascade
Skin secretions
Saliva and tears
Mucous membranes
Complement cascade
Which type of molecule is produced by viral-infected cells to communicate to non-infected cells of the presence of a virus?

Complement
Interleukin
Pyrogen
Interferon
Antigen
Interferon
When a localized area exhibits increased capillary filtration, hyperemia, and swelling, this is an indication that

fever is developing.
inflammation is occurring.
antigens are present.
antibodies are phagocytizing target cells.
an immune response is underway
inflammation is occurring.
Which of the following is a nonspecific barrier defense?

Natural killer cells
Macrophages
Antibodies
Complements
Mucous membranes
Mucous membranes
Which cells of the innate immune response are responsible for detecting and destroying parasites?

Mast cells
Eosinophils
Neutrophils
Natural killer cells
Eosinophils
Which cell does NOT have a direct role in phagocytosis?

Kupffer cell
Macrophage
Neutrophil
Basophil
Eosinophil
Basophil
Which of the following actually kills invading microbes?
lysozymes
stomach acid
intestinal enzymes
all of the above
all of the above
The inflammatory response includes all of the following except
vessel constriction
temperature increase
increased blood flow
phagocyte attack
vessel constriction
The secretion of antibodies by lymphocyte B cells provides
A) cell-mediated immunity
B) passive immunity
C) humoral immunity
D) permanent immunity
humoral immunity
The immunoglobulin found in a mother's milk is
A) IgM
B) IgA
C) IgE
D) IgG
IgA
Which of the following are autoimmune diseases
A) heart disease
B) Hashimoto's thyroiditis
C) erythroblastosis fetalis
D) systemic lupus erythematosus
E) both b and d
both b and d
The proteins secreted by plasma cells are called
A) MHC
B) complement
C) antigens
D) cytokines
E) antibodies
antibodies
Precursors of macrophages are called
A) T cells
B) killer cells
C) B cells
D) plasma cells
E) monocytes
monocytes
The immune response is terminated or decreased by
A) suppressor B cells
B) suppressor T cells
C) both of the above
D) none of the above; the immune response can only be stimulated, not terminated
suppressor T cells
Which type of T cell lyses cells that have been infected with viruses?
A) inducer T cells
B) helper T cells
C) cytotoxic T cells
D) suppressor T cells
E) none of the above
cytotoxic T cells
All of the following cells are phagocytic except for
A) basophils
B) neutrophils
C) lymphocytes
D) eosinophils
E) all of the above are phagocytic
lymphocytes
What holds together the four polypeptide chains of an antibody?
A) disulfide bonds
B) light chains
C) heavy chains
D) complement proteins
E) MHC proteins
disulfide bonds
Of the five classes of antibody heavy chains, which one's function is still partially unclear?
A) IgE
B) IgM
C) IgG
D) IgA
E) IgD
IgD
Which of the following cells participate in nonspecific defense responses when your body is invaded by microbes?
A) natural killer cells
B) macrophages
C) neutrophils
D) all of the above
E) none of the above
all of the above
Cytotoxic T cells are called into action by the:
A) presence of interleukin-1
B) presence of interleukin-2
C) presence of neutrophils
D) decrease in the number of B cells
E) decrease in the number of antibodies
presence of interleukin-2
Complement and antibody are similar in that both:
A) are produced by mast cells.
B) may make bacteria more attractive to phagocytes.
C) have two identical antigen-binding sites.
D) are activated in an inflammatory cascade
may make bacteria more attractive to phagocytes.
Hypersensitivity reactions:
A) are sometimes mediated by IgE.
B) may involve immune complexes.
C) may involve complement, histamine, neutrophils or IgG.
D) all of the above
all of the above.
Which cell is correctly matched with its secretion or function?
A) T-lymphocyte -- IL-1
B) mast cells -- histamine
C) macrophage -- IgA
D) eosinophil -- clotting
mast cells -- histamine
All of the following are part of our antigen specific defense mechanisms except:
A) acute inflammation.
B) lymphocytes.
C) antibody production.
D) macrophages.
acute inflammation