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28 Cards in this Set
- Front
- Back
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Adaptive immunity has high ___________, _________ reaction and develops ___________.
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Specificity, Slow, Memory
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Adaptive Immunity is quicker upon secondary exposure. True or False?
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True
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Name the two types of adaptive immunity.
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Humoral, Cell-mediated
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Humoral Immunity is the principal defence against ______________ microbes.
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Extracellular
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Extracellular microbes include fungi, helminths and some bacteria. True or False?
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True
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Humoral immunity deploys circulatory soluble mediators such as ____________.
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Antibodies
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Humoral immunity is mediated by which 2 types of immune cell?
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Th2 cells, B cells
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There are 3 effector responses generated to deal with
extracellular pathogens. What are they? |
Macrophage suppression, Antibody production, Eosinophil activation
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Naive CD4+ T cell differentiate and proliferate into Th2 cells after being signalled by an __________________.
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Antigen Presenting Cell (APC)
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Th2 cells release which interleukins to induce macrophage suppression?
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IL-10, IL-4
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Th2 cells release which interleukin to induce antibody production?
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IL-4
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Th2 cells release which interleukin to induce eosinophil activation?
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IL-5
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MHC II expressing APC stimulate the differentiation of CD4+ helper T cells into Th2 cells. True or False?
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True
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A co-stimulatory signal can also stimulate the differentiation of CD4+ helper T cells into Th2 cells. True or False?
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True
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The activation of B cells via IL-4 allows for Antibodie production for opsonisation/clearance. True or False?
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True
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There were 5 antibody isotypes shown on the slide for this topic. What were they? (Hint: They are immunoglobulins)
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IgD, IgG, IgA, IgM, IgE.
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Most antibodies look like the letter Y. What are the two protrusions at the top of Y called on an antibody?
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Fab Region
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Most antibodies look like the letter Y. What is the stem of the Y called on an antibody?
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Fc Region
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IgD is a membrane receptor. True or False?
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True
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IgG is a membrane receptor. True or False?
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False
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IgM is a membrane receptor. True or False?
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True
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IgG is used for opsonisation. True or False?
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True
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IgE is seen characteristically at sites of allergy. True or False?
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True
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IL-4 induces what antibodies?
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IgE and IgG1
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IL-2, IL-4 and IL-5 induces what antibody?
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IgM
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IFNy induces what antibodies?
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IgG2a and IgG3
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TGFb induces what antibodies?
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IgA and IgG2b
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Certain humoral responses can result in hypersensitivity and damage to the host. True or False?
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True
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