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10 Cards in this Set

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  • Back

What is a nucleicacid?

· DNA and RNA both are nucleic acids




Themonomer of a nucleic acid is anucleotide, a nucleotide polymer is called a polynucleotide (a chain of monomers)

Polynucleotidesconsist a long sequence of four different nucleotides

DNA= A, C, G, T


RNA= A, C, G, U

sugar-phosphate backbone

· Nucleotides are joined by covalent bonds betweenthe sugar of one nucleotide and the phosphate of the next in a long chaincalled the sugar-phosphate backbone

· Eachnucleotide consists of three components:

1. nitrogenous base (A, T, C, G for DNA or A, U, C,G for RNA)


2. sugar (deoxyribose for DNA, ribose for RNA)3. phosphate group

Thefour nucleotides in DNA differ in their nitrogenous bases

1. Thymine (T) and cytosine (C)are single-ring structures • Thesebases are pyrimidines


2. Adenine (A) and guanine (G)are larger, double-ring structures. • These bases are purines

• RNA and DNA polynucleotides have the samechemical structure except:

1. RNA has a similar base called uracil (U)instead of thymine


2. RNA ribose instead of deoxyribose


3. RNA is single stranded

Who determinedthat DNA is a double helix

• JamesWatson and Francis Crick determinedthat DNA is a double helix

Composition of a DNA. What letters go with what

Arung represents a pair of bases connected by hydrogen bonds. o


Thebase-pairing rules dictate combinations of bases that form the rungs § Adenine (A) bonds with Thymine (T)§ Cytosine (C) bonds with Guanine (G)

· A cell must duplicate genetic information toreproduce

mitosis

Origin of replication

· Origin of replication is the site DNA where replicationstarts to occur