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19 Cards in this Set
- Front
- Back
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What are the criteria for neurodegenerative diseases? (3)
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Loss of neurones
Progressive Irreversible |
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What are the symptoms of Alzheimer's disease?
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Memory loss and dementia
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Climsiness is in the (early/late/latest) stage of Alzheimer's disease
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Early
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Bradykinesia is in the (early/late/latest) stage of Alzheimer's disease
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late
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Hallucinations is in the (early/late/latest) stage of Alzheimer's disease
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late
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Mutism is in the (early/late/latest) stage of Alzheimer's disease
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latest
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The pathology of Alzheimer's disease is a widened (sulci/gyri) and a narrowed (sulci/gyri)
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sulci
gyri |
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Which pathway is particularly affected in Alzheimers disease?
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Cholinergic pathways
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The current treatment is based on...
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AChE inhibitors
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What is the enzyme that breaks down acetylcholine?
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Cholinesterase
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What is the cause of Multiple sclerosis?
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Autoimmune disease which affects the oligodendrocytes which degrades the myelin sheath
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What is the symptoms of Parkinson's disease?
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Extrapyramidal disorder
Loss of movement Increased muscle tone |
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What is the pathology of a patient with Parkinson's disease?
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a diminished substantia nigra
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Huntington's disease is autosomal (dominant/recessive)
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dominant
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Huntington's disease is a ____________ repeat
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polyglutamine
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In Huntington's Irritability, moodiness and anti-social behaviour is classified as (Gross choreiform movement/demetia)
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demetia
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In Huntington's Fidgeting and restlessness is classified as (Gross choreiform movement/demetia)
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Gross choreiform movement
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In Huntington's there is a loss of neurones in the ___________ and the ___________
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cerebral cortex
corpus stratium |
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In Huntington's it targets which receptors?
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GABAergic and cholinergic receptors
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