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77 Cards in this Set

  • Front
  • Back
What are the fundamental themes in biology?
structure = function
cells respond to their environment.
Who invented microscopy?
Anton van Leeuwenhoek.
Magnification
ratio of an objects image size to its real size.
Resolution
measure of the clarity of the image.
What wavelengths have better resolution?
shorter wavelengths.
Scanning electron microscopes
focus a beam of electrons onto the surface of a specimen; provides 3D image.
Transmission electron microscopes
focus a beam of electrons through a specimen; flat, internal plane from cell.
Why are electron microscopes better?
electrons have shorter wavelength and therefore better resolution.
What do all cells have in common?
plasma membrane, cytosol, genetic info, ribosomes.
Prokaryotes
no nucleus, cell wall, no membrane bound organelles, smaller, simple.
Eukaryotes
nucleus, no cell wall, membrane bound orgs, bigger, complex.
Eubacteria Kingdom:
bacteria, cyanobacteria.
Arachaebacteria Kingdom
animalia, fungi, plantae, protista.
What sets limits on the size of a cell?
logistics of cellular metabolism. cell can only grow to the extent that it can support itself.
Does volume or surface area increase more?
Volume; smaller object has a greater surface-to-volume ratio than a larger object.
Plasma Membrane
selective barrier that allows sufficient passage of oxygen, nutrients, waste to service the volume of cell.
What increases surface area on a cell?
microvilli.
Nucleus
contains DNA.
Nuclear Envelope
encloses the nucleus, seperating it from cytoplasm.
Nuclear Lamina
lines inside of nuclear membrane.
Nuclear Matrix
framework of fibers extends throughout the nuclear interior.
Chromosomes
DNA in discrete units.
Chromatin
complex of proteins and DNA coiled together.
Nucleolus
dense center of nucleus; synthesis of rRNA. rRNA assembled into large and small subunits.
Ribosomes
Make proteins using directions from DNA; made of rRNA and protein.
Endoplasmic Reticulum (ER)
2 distinct regions: smooth ER w/ no ribosomes; and rough ER w/ ribosomes attached; continuous with the nuclear envelope.
Smooth ER
synthesizes lipids, metabolizes carbs, store calcium(muscles), detoxifies drugs(liver).
Rough ER
produce secreted glycoproteins to leave the cell; polypeptides distributed by vesicles.
Golgi Apparatus
polar membrane, differs in thickness and molecular composition; manufactures polysaccharides, directs vesicles to proper sites, modifies glycoproteins.
Lysosomes
membrane sac, holds hydrolitic enzymes, acidic; breakdown proteins, carbs, fats, nucleic acids. (phagocytosis)
How do lysosomes work?
engulf smaller organisms and break it down in acidic environment; breaks down into monomers.
Macrophage
immune cell, ingests microorganisms.
Autophagy
recycle organelles and macromolecules; membranes fuse and enzymes break it down to return to cytosol for reuse by the cell.
Tay-Sachs Disease
rare genetic mutation, lack hydrolytic enzymes to break down lipids; build in lysosomes and accumulation of fat impaires brain.
Vacuoles
large vesicles-membrane bound sacs.
Food Vacuole
formed by phagocytosis, fuses w/ lyso.
Contractile Vacuole
pump xcess water out of cell to maintain salt concentration, protists.
Central Vacuole
only in plants and effect plant size as it absorbs water.
Mitochondria
sites of cellular respiration = ATP.
Ribosomes and DNA within; have folds on inside to increase surface area.
Respiration
metabolic process generates ATP by extracting energy from sugars & fats, using oxygen.
Chloroplasts
organelle called a plastid, contain chlorophyll green pigment and enzymes for photosynthesis. replicate themselves.
Thylakoids
membranous sacs within a chloroplast; site of light rxns in photosynthesis.
Stroma
internal fluid of chloroplast; contains ribosomes and DNA.
Peroxisomes
produce hydrogen peroxide and use special enzymes (peroxidase) to convert it to water; use oxygen to catabolize fatty acids.
Motility
cell movement and parts within the cell.
Components of cytoskeleton
microtubules, microfilaments, intermediate filaments.
Microtubules
maintain cell shape, cell motility, seperate chromosome, organelle movement.
Centrosomes
Region near the nucleus, microtubule-organizing center.
Dynein
motor protein drives the bending movements;
Actin Filaments
muscles.
Intermediate Filaments
class of cytoskeletal fibers, made of keratin proteins, dont unassemble; affects shape and organelle position, makes up nuclear lamina.
Primary cell wall
thin and flexible.
What covers animal cells?
extracellular matrix(ECM).
ECM
made of glycoproteins(collagen); connected to cell by fibronectin.
ECM Functions
Support, adhesion, movement.
How do neighboring cells communicate?
by direct physical contact.
Desmosomes
fasten cells together into strong sheets.
Gap Junctions
provide cytoplasmic channels between adjacent animal cells.
Cis face
receives vesicles from ER.
Trans face
sends vesicles out to other sites in cell.
How does a golgi apparatus sort a vesicle?
puts external receptor that recognizes certain docking sites on specific cells.
What chemical does peroxisomes produce?
hydrogen peroxide.
Cytoskeleton
network of fibers extending throughout the cytoplasm; supports cell and maintains shape, very strong, anchorage for organelles, quickly dismantled and reassembled, motility.
What travel along microtubules?
vesicles and organelles.
Centriole
within a centrosome, each w 9 triplets of microtubules in a ring.
What do microtubules control?
the beating of cilia and flagella.
Basal body
anchors the cilia and flagellum.
What connects microtubule doublets in cilia and flagellum?
dynein protein.
Microfilaments
actin filaments; linear. maintain cell shape, muscle contraction, cell division, cell motility.
Myosin
thicker filaments parallel w/ actin.
Muscle contraction
myosin and actin sliding past each other.
Plasmodesmata
chanels between adjacent plant cells; unify most of plant into one living continuum as cytosol seeps through and connects environments.
Proteoglycan network
small core protein with many carbohydrates chains covalently attached.
Tight Junctions
membranes of neighboring cells are pressed together, preventing leakage of extracellular fluid.
Cisternae
large membrane folds of the golgi apparatus.
Endomembrane system
vacuoles, lysosomes, plasma membrane, golgi apparatus, ER, nuclear envelope. components are either continuous or connected by transport vesicles.
Cilia and Flagella
A core of microtubules sheathed by the plasma membrane.