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20 Cards in this Set

  • Front
  • Back

Where does glycolysis occur and what other net gains?

In the cytoplasm and it produces 2 pyruvate, (4-2=2) ATP and 2 NADH molecules

What is the sequence of reactions for aerobic respiration?

Glycolysis, link reaction, krebs cycle and oxidative phosphorylation

What are the 4 steps and the name of the 4 steps of glycolysis?

1. Phosphorylation- 2 ATP molecules are hydrolysed and a phosphate group attaches to either end of the glucose molecule forming hexose bisphosphate


2. Lysis- this unstable molecule breaks down into 2 triose phosphate molecules


3. Phosphorylation- another phosphate group coming from the cytoplasm attaches to the ends of the TP molecules forming triose bisphosphate


4. Dehydrogenation- The 2 TBP molecules are oxidized removing the h atoms which are accepted by energy coenzymes forming 2 NADH, 4 ATP and 2 pyruvate molecules

What are adaptations of the cristae?

They are folds which increase SA for maximum oxidative phosphorylation

What is the difference between the mitochondrial inner membrane and intermembrane space?

The inner membrane contains the electron transport chains and ATP synthase but the intermembrane space is where proteins are pumped into

What is another name for the link reaction and where does it occur?

Oxidative decarboxylation occurs in the mitochondria matrix

What happens to the starting pyruvate molecule in the link reaction?

Undergoes decarboxylation catalysed by pyruvate decarboxylase producing CO2.


it is then oxidized and an H atom is removed and accepted by NAD to form NADH

What is the final product of the link reaction?

Acetylcoenzyme A forms when the acteyl group combines with coenzyme A

Where does the krebs cycle occur?

In the mitochondrial matrix

What is the net gain of molecules of the krebs cycle using one glucose molecule?

6 NADH, 2 FADH2, 2 ATP molecules from 2 cycles using pyruvate

What are the steps for the krebs cycle?

1. Acetyl CoA breaks down into CoA and acetate which combines with a 4C oxaloacetate to form citrate


2. The citrate undergoes decarboxylation and dehydrogenation producing a NADH, CO2 and a 5C molecule


3. The 5C compound undergoes further decarboxylation and dehydrogenation eventually reforming oxaloacetate

What are the 4 differences between NAD and FAD?

NAD takes part in all stages of respiration but FAD only takes part in the krebs cycle


NAD accepts 1 H but FAD accepts 2 H


NADH is oxidised at the start of the ETC but FADH2 is oxidised further along the chain


NADH results in 3 ATP but FADH2 results in 2 ATP

Where does oxidative phosphorylation occur?

In the membranes of cristae

What happens to NADH and FADH2 when they enter oxidative phosphorylation?

The H atom dissociates into H+ and high energy e- which are used to synthesise ATP by chemiosmosis

How is the proton gradient created and maintained in oxidative phosphorylation?

The oxidation and reduction of electron carriers releases energy which is used to create this gradient

What is the final electron acceptor in oxidative phosphorylation and what are the products?

O2 which is combined with H+ ions to form water

Where is substrate level phosphorylation shown in respiration?

Krebs cycle and glycolysis (formation of triose bisphosphate)

What are obligate anaerobes?

Organisms that can't survive in oxygen such as prokaryotes that only anaerobically respire

What are facultative anaerobes?

These organisms can synthesise ATP from aerobic respiration in the presence of oxygen but can also switch to anaerobic

What are obligate aerobes?

These can only synthesise ATP in the presence of oxygen even though some of it's cells e.g. muscles may act as facultative anaerobes