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10 Cards in this Set
- Front
- Back
Ligand gated channel receptors
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signal molecule binds as a ligand to the protein receptor, which either opens or closes the gate
-very important in the nervous system |
|
G-Protein linked receptors
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-works as molecular switch, if GDP is attatched, switch is off, but if GTP is attatched, switch is on
-signal moelcule binds to extracellular part of receptor, which activates receptor, then binds to inactive side of G-protein, making GTP replace GDP |
|
Tyrosine Kinase
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-first individual polypeptides, then bind and become dimers: activae each other, adds phosphate from an ATP molecule on tail of other polypeptide
-relay proteins recognize receptor proteins, changes structure of protein, leads to cellular response |
|
What are the 3 steps in cell signaling?
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1) Reception
2) Transduction 3) Response |
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What are second messengers?
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-small,nonprotein, water-soluble ions that spread throughout cell by diffusion
|
|
Ligand gated channel receptors
|
signal molecule binds as a ligand to the protein receptor, which either opens or closes the gate
-very important in the nervous system |
|
G-Protein linked receptors
|
-works as molecular switch, if GDP is attatched, switch is off, but if GTP is attatched, switch is on
-signal moelcule binds to extracellular part of receptor, which activates receptor, then binds to inactive side of G-protein, making GTP replace GDP |
|
Tyrosine Kinase
|
-first individual polypeptides, then bind and become dimers: activae each other, adds phosphate from an ATP molecule on tail of other polypeptide
-relay proteins recognize receptor proteins, changes structure of protein, leads to cellular response |
|
What are the 3 steps in cell signaling?
|
1) Reception
2) Transduction 3) Response |
|
What are second messengers?
|
-small,nonprotein, water-soluble ions that spread throughout cell by diffusion
|