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82 Cards in this Set

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Cellular respiration
complex process in which cells make ATP (adenosine triphosphate) by breaking down organic compounds
Link autotroph and/or heterotroph with the appropriate functions:
1. photosynthesis
2. cellular respiration
1. autotroph only
2. autotroph and heterotroph
Name the 2 stages of Cellular Respiration
1. Glycolysis
2. Aerobic respiration
Fermentation
The combination of glycolysis and anerobic pathways
aerobic

anerobic
with oxygen

without oxygen
Glycolysis
The first step of cellular respiration, in which organic compounds (proteins, carbohydrates,and fats), are converted into three carbon molecules of pyruvic acid,and a small amount of ATP and NADPH. It is an anerobic reaction.
Aerobic respiration
The second step of cellular respiration, with oxygen present, pyruvic acid is broken down and NADH is used to make a large amount of ATP
LIGHT REACTIONS + CALVIN CYCLE=
PHOTOSYNTHESIS
GLYCOLOSIS + AEROBIC RESPIRATION=
CELLULAR RESPIRATION
How is lactic acid, ethyl alcohol made?
Process of fermentation, wherein pyruvic acid in an anerobic pathway breaks down into these compounds.
OXIDATION
LOSS OF ELECTRONS
REDUCTION
GAIN OF ELECTRONS
give the equation for cellular respiration
C6H12O6 + 6O2 -----------
6CO2 + 6H2O + energy (ATP)
Glycolysis
Stage 1 of cellular respiration in which one six-carbon molecule of glucose is oxidized to produce two three-carbon molecules of pyruvic acid. There are specific enzymes needed and all the steps take place in the cytosol.
Step 1 of Glycolysis
Two phosphate groups are attached to one molecule of glucose forming a new 6carbon compound that has two phosphate groups. The phosphate groups are supplied by two ATP.
Step 2 of glycolysis
The 6 carbon compound is split into 2 three carbon molecules, G3P, gyleraldehyde 3-phosphate
(G3P also produced in The Calvin cycle in photosynthesis)
Step 3 of Glycolysis
The two G3P are oxidized and each get a phosphate group yielding 2 molecules of a new three carbon compound.
The oxidation of G3P is done by reduction of two NAD+ to NADH.
Name 3 organic molecules used as reductants (molecules to accept electrons in redox reactions) and tell if it is P or C
NAD+ glycolysis of cellular respiration
NADP light reaction of photosynthesis
FAD Kreb's cycle of cellular respiration
Step 4 (final) of glycolysis
the phosphate groups (4, 2 fro step 1 and 2 from step 3) are removed to yield two molecules of the 3 carbon molecule, pyruvic acid. The phosphates are attached to ADP to yield 4 ATP
What is the net yield of ATP in glycolysis?
2 ATP

2ATP are used in step 1, and 4ATP are produced in step 4.
Glycolysis has a net yield of ____ATP for every ___molecule of glucose that is converted into ___________.
two , one, pyruvic acid
If oxygen is present Cellular respiration continues as _______ enters the pathways of _______ respiration.
pyruvic acid
aerobic
If oxygen is absent, anerobic conditions, Cellular respiration continues as ________enters __________.
pyruvic acid (product of glycolysis)
fermentation
Note fermentation takes place in the cytosol.
Does fermentation produce ATP?
What is recycled from fermentation?
NO

NAD+ from NADH
This allows for the continued production of ATP in glycolysis.
What causes fermentation pathways to differ?
What is the common factor of all fermentation pathways?
the type of different enzymes used, and the compounds produced///////they all start with pyruvic acid, they recycle NAD+ from NADH
Name 2 common fermentation pathways, and their products
LACTIC ACID- dairy products: cheese, buttermilk, yogurt, sour cream
ALCOHOLIC- wine and beer, breads
Performed by microorganisms
involves the transfer of one hydrogen atom and the addition of one free proton H+ to pyruvic acidand the oxidation of NADH to NAD+
LACTIC ACID FERMENTATION
Name an example of fermentation in the human body
muscles cells during strenuous excercise, when O2 is depleted by the cells rapidly in glycolysis. This results in acidic environment that can reduce the capacity of the cells to contract-leading to muscle fatigue, pain, cramps
Where is lactic acid in the human body transported? Why?
thru simple diffusion it enters the blood and returns to the liver where it can be converted back into pyruvic acid.
Performed by yeast (Saccharomyces cerevisiae), a fungus in 2 steps. Step 1 a CO2 molecule is removed from pyruvic acid leaving a 2carbon compound and step2 two hydrogen atoms are added to the 2carbon to form ethyl ________.
ALCOHOLIC FERMENTATION
alcohol
What can the released CO2 in the alcoholic fermentation pathway be used for
the 'carbonization' of sparkling wines, champagne
used to cause bread to rise in baking (Judy's rolls)
KILOCALORIE
a unit of measurement of energy
1 unit= 1,000 calories
kilo
Greek, means thousand
calor
Latin, means heart
EFFICIENCY OF GLYCOLYSIS===2%
Energy required to make ATP
------------------------------------------
Energy released by oxidation of glucose
If the energy of glucose oxidation in glycolysis yields only 2% of the total contained energy of glucose, where is remainder stored?
It is still held within pyruvic acid
In the history of life on Earth, what energy pathway did the first organisms use?
glycolysis, by the prokaryotes, bacteria
In the evoloutionary process what did the advent of photosynthetic organisms offer?
Oxygen as a byproduct of photosynthesis that may have stimulated the evolution of organisms that make most of their ATP through aerobic respiration
Aerobic respiration produces nearly ______times as much ATP as is produced by glycolysis.
TWENTY
What are the two major stages of aerobic respiration?
the Krebs cycle and the electron transport chain (chemiosmosis, the use of the energy released as protons move across a membrane to make ATP)
What makes more ATP, the Kreb's cycle or the electron transport chain via chemiosmosis?
the electron transport chain
In a prokaryotic cell such as a bacteria, where does cellular respiration take place?
the cytosol of the cell
In a eukaryotic cell where does the Kreb's cycle and electron transport take place?
inside the mitochondria
Where does the Kreb's cycle take place in an eukaryotic cell?
in the mitochondrial matrix
Where does the electron transport chain work inside an eukaryotic cell?
in the folds of the inner membrane, the cristae, of the mitochondria
Where is the mitochondrial matrix located?
the space inside the inner membrane of a mitochondrion
What does pyruvic acid,, the product of glycolysis (occurs in the cytosol) go to become Acetyl CoA? What enzyme is used?
the mitochondrial matrix, acetyl coenzyme A synthetase
State the reaction for conversion of pyruvic acid (3carbon) to Acety Coenzyme A (2 carbon)
pyruvic acid(3C) + coenzyme A synthetase will yield CO2 (1C) and the reduction of one molecule of NAD+ to NADH + H
What does the Kreb cycle break acetyl CoA into?
CO2, hydrogen atoms, and ATP
Step 1 of Kreb's cycle
Acetyl CoA (2C) combines with oxaloacetic acid (4C) to produce citric acid (6C); this reaction will regenerate coenzyme A
Step 2 of Kreb's cycle
citric acid releases CO2, and a Hydrogen atom to make a 5carbon compound. This is a redox step in that citric acid is oxidized and NAD+ is reduced to NADH.
Step 3 of Kreb's cycle
The 5carbon compound now releases a CO2 and a hydrogen atom forming a 4carbon compound. NAD+ is reduced to NADH and a molecule of ATP formed from ADP.
Step4 of Kreb's cycle
The 4 carbon compound releases a Hydrogen atom to from another 4carbon compound. The H+ reduces FAD to FADH2.
Step 5 of Kreb's cycle
The 4 carbon compound releases a hydrogen atom to regenerate oxaloacetic acid, which keeps the Krebs cycle going. The electron also reduces NAD+ to NADH.
What produces more ATP, glycolysis or the Kreb's cycle?
Neither!, they both yield 2 ATP
At what stage of cellular respiration does most of the energy transfer from glucose to ATP occur?
The second stage: Electron transport chain and chemiosmosis
How many NADH and FADH2 molecules from one glucose molecule enter the final stage of cellular respiration?
10 NADH (2 from glycolysis, 2 from conversion of pyruvic acid to acetyl CoA, and 6 from the Krebs cycle)
What is the second stage of cellular respiration?
electron transport chain linked with chemiosmosis
Where is the electron transport chain of cellular respiration located in a prokaryotic cell?
in the cell membrane
Where is the electron transport chain of cellular respiration located in an eukaryotic cell?
It is in the folds of the inner membrane of the mitochondria. These folds are called the cristae.
Step 1 of the electron transport chain of cellular respiration
NADH and FADH2 give up electrons. NADH is the first donor and FADH2 does so further down the chain. Both molecules are also giving up protons(hydrogen ions, H+)
Step 2 of the electron transport chain of cellular respiration
The electrons are passed down the chain from molecule to molecule, losing energy
Step 3 of the electron transport chain of cellular respiration
the energy lost from the electrons of step3 are used to pump protons from the matrix. This builds a concentration gradient of protons across the inner membrane, and a resulting electrical gradient
(protons carry a positive charge)
Step 4 of the electron transport chain of cellular respiration
What drives the synthesis of ATP in the second stage of cellular respiration
The concentration and electrical gradients of protons. As protons move through the ATP synthetase and down their concentration and electrical gradientsATP is made from ADP and P.
Step 5 (final) of electron transport and chemiosmosis in cellular respiration
Oxygen is the final acceptor of electrons that passed down the chain. Oxygen also accepts protons that were part of the hydrogen atoms from NADH and FADH2. The electrons, oxygen and protons all combine to form water.
State the final step of electron transport and chemiosmosis in cellular respiration, in equation form
O2 + 4e + 4H+ _____ 2H2O
What might result from dysfunction of mitochondria?
aging symptoms, Alzheimer's disease, and cancer
(thru the consequences of free radicals)
Define free radicals
very reactive atoms with one or more unpaired electrons that can quickly react with DNA, and protein and cause disruption to normal cell activities. Free radicals are made of stray electrons (leaked from mitochondria) that combine with oxygen
apoptosis
programmed cell death
it is believed that signals from mitochondria may initiate or continue the apoptosis process)
Do mitochondria have their own DNA?
YES
What is the importance of oxygen in the process of cellular respiration?
Oxygen must be present to accept electrons from the last molecule in the electron transport chain; otherwise, chemiosmosis would halt and ATP would cease to be produced
What is the maximal number of ATP molecules made in cellular respiration?
38 (maximal yield)
What is the actual production number of ATP per glucose molecule?
36, because 2ATP are consumed in the active transport of NADH across the inner membrane of the mitochondrion
EFFICIENCY OF CELLULAR RESPIRATION=
Energy required to make ATP
---------------------------------------------
Energy released by oxidation of glucose 39%
What is more efficient, cellular respiration or glycolysis?
Cellular respiration (20X more efficient)
Glycolysis
Glucose is converted into pyruvic acid, producing a small amount of ATP and NADH
Aerobic Respiration
Pyruvic acid is converted into CO2 and water in the presence of oxygen, producing a large amount of ATP
Equation for complete oxidation of glucose in cellular respiration
C H 0 + 6H 0------- 6CO + 6H O + energy(ATP)
What type of molecules can be used as fuel in cellular respiration?
GLUCOSE, breakdown products of fats, proteins, and carbohydrates
True or False:
THe products of photosynthesis are reactants in cellular respiration, and the products of cellular respiration are reactants in photosynthesis
True:
6CO + 6H O---------- C H O + 6O
True or False:
Cellular Respiration is the reverse of photosynthesis
False
State a role for cellular respiration, other than the obvious of producing ATP
to build specific compounds that may not be contained in the food that a heterotroph consumes ( 10 of the amino acids needed by the human body can be made with compounds diverted from the krebs cycle)