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46 Cards in this Set

  • Front
  • Back

Received Nobel prize in 1962 for discovering structure of DNA

Watson, Crick, and Wilkins

Allows for double helix to form

Sugar phosphate backbone

Type of macromolecule DNA is

Nucleic acid

The gene's sequence is copied from DNA to mRNA

Transcription

Gene's sequence is encoded in mRNA which directs the production of a protein

Translation

Enzyme used in transcription

RNA polymerase

Help to synthesize

Ribosomes

Multiple amino acids form

Polypeptide

Where does transcription occur

Nucleus

Needed for translation

Free amino acids


Ribosomal unit


Transfer RNA

Decoder ring works in multiples of 3

tRNA

Universal starter

Methionine (AUG)

A sequence of bases in a DNA molecule that carries the info necessary for producing a functional product, usually a protein molecule or RNA

Genes

Different versions of a gene that code for the same trait

Alleles

A full set of DNA an organism carries

Genome

In eukaryotes, the genome is divided among smaller, linear strands of DNA

Chromosomes

Non coding regions of DNA


May take the form of short (or long) sequences that are repeated thousands of times

Introns

Useful parts of DNA

Exons

Genome

Chromosome

Gene

Three base sequence in mRNA

Codon

Three components of nucleotides

A molecule of sugar


A phosphate group


A nitrogen containing molecule (base)

Alteration in DNA bases

Mutations

Occur when one base pair in the DNA is substituted for another, or when a base pair is inserted or deleted

Point mutation

3 types of point mutation

Nucleotide substitution


Nucleotide insertion


Nucleotide deletion

Changes to the overall organization of the genes on a chromosome (gene moves)

Chromosomal aberrations

3 types of chromosomal aberrations

Gene deletion


Gene relocation


Gene duplication

Human genes for breast cancer

BRCA1 & BRCA2

Increase risk of mutation

Spontaneous mutation


Radiation-induced mutations


Chemical-induced mutations

Generally exploits the use of cellular or cellular components to develop new technology

Biotechnology

How PCR works

Small amount of DNA is collected


Chopped up (restriction enzyme)


Copied

The study of genomes

Genomics

With your PCR amplified sample you can identify which genes are turned on in any individual

Microarray

Careful selection of genes/traits to alter the original state of an organism

Genetic engineering

You can genetically modify food to

Make it larger


Make it resistant to bacteria/viruses


Longer shelf life


More nutritious

The complementary base pairs in a DNA molecule are stabilized by...

Hydrogen bonds

DNA can be found in...

Dead skin cells


Saliva


Blood

The double helix model of DNA was exciting to the scientific community because...

It explained how genetic material could be duplicated by means of the complementary strands

Most genes come in alternative forms called

Alleles

DNA is a macromolecule that stores info. Which component of DNA is the source of this information?

The base

The highest percentage of non-coding DNA is found in

Eukaryotes, except yeast

The central dogma of molecular biology states that

DNA is transcribed into RNA which is translated into a protein

The eukaryotic cell cycle consists of four phases. In this order

Mitosis, gap 1, DNA synthesis, and gap 2

The majority of a eukaryotic cell's life is spent in

Interphase

Mitosis results in

Daughter cells with the same number and composition of chromosomes