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50 Cards in this Set

  • Front
  • Back

The cellular basis of muscular distrophy is that some of a child’s muscle cells:

Lack a protein that enables them to withstand the force of contraction

A researcher identifies an abnormality in a protein that causes a particular inherited illness. To develop a treatment, it would be helpful to know

Which cells are affected and how to replace the proteins function in them

What does diploid mean?

Diploid means a pair: body cells have 2 copies of the human genome

The approximate number of differentiated cell types in a human body is

260

Humans belong to what domain?


Distinguished by which cells?

Eukarya


Organelles

Ribosomes are in the cells of

All organisms

The major macromolecules that make up cells are

Carbohydrates, proteins, lipids, and nucleic acids

About how many average sized bacteria could fit into a human cell?

1,000

Organelles protect a cell by

Sequestering bio chemicals that could dismantle other cellular structures

The nuclear lamina is:

A fibrous layer that lines the inner face of the nuclear membrane

In a human cell, the genetic material is in the where?

Nucleus

The organelles that contain DNA are the what?

Nucleus & mitochondrion

What is the sequence of events to produce a protein that is secreted?

A hormone signals the gene that encodes the protein to be transcribed into mRNA in the nucleus. The mRNA is translated into protein on the ER, then processed and folded in the Golgi apparatus, and then sent out of the cell in a vesicle.

The organelle that consists of a stack of flat membrane enclosed sacs is the

Golgi apparatus

The organelles that is the equivalent of a cellular garbage disposal system is the

Lysosome

A bubble like structure that ferries molecules such as cholesterol to lysosomes is an

Endosome

In mitochondria

Energy from nutrients is converted into a form that a cell can use.

The cell type with the most mitochondria is

Muscle

Cristae are what

Membranous structures that are parts of mitochondria

In a DNA molecule, the sugar phosphate backbone is the same in everyone but the base sequence is different in everyone. A plasma membrane is similar conceptually to dna in that :

The lipid belayer is the same in everyone but the nature and pattern of the molecules embedded in it differ

A molecule that binds a cell surface receptor is called a

Ligand

The internal scaffolding of a cell consists of

Microtubules and microfilamente

Cilia are made of what

Microtubules

In hereditary spherocytosis red blood cells lose their doughnut shapes, ballooning out, because they have abnormal

Ankyrin molecules, which bind spectrum rods to the plasm membranes

The cytoskeleton component that consists of different protein types in different cell is

An intermediate filament

The approximate percentage of our cells that are replaced daily is

10%

The 2 major stages of the cell cycle are

Interphase and mitosis

The cell cycle is a series of events a cell Undergoes as it prepares to

Divide

DNA replicates during what phase of the cell cycle?

S

The order of events in the cell cycle is

G1 to S to G2 to mitosis

At the point in the cell cycle when mitosis begins

Each chromosome consists of two identical chromatids joined at the centromere

Chromosomes coil tightly around chromosomal proteins and condense during

Prophase

In which disease is signal transduction abnormal

Neurofibromatosis type 1

In which disease is cellular adhesion abnormal?

Arthritis

The defining characteristic of a stem cell is

Self renewal

A difference between a stem cell and a progenitor cell is that

A progenitor cell cannot self-renew and a stem cell can

A cell that can divide to give rise to any cell type including those of membranes that support the developing embryo is

Totipotent

An experimental treatment for amyotrophic lateral sclerosis which causes gradual loss of the ability to move sends four genes into cells sampled from a patients skin. This procedure reprograms the cells, which are then exposed to molecules and genes that stimulate them to develop as healthy versions of the cells affected in the disease. These cells are implanted into the patient. They are

Induced pluripotent stem cells

Human embryonic stem cells that are used in research are

Cultured in laboratory dishes from inner cell mass cells taken from a 5 day embryo

Adult stem cells are more accurately called tissue specific or somatic stem cells because

They are also present at prenatal stages of development

Human stem cells are valuable in drug development because they can be used to

Replace experimental animals such as rats and mice

Cells contain twice the normal number of chromosomes briefly during

Anaphase

During S phase replicated chromosomes are joined at their

Centromeres

The part of a chromosome that shortens with each cell division functioning as a clock is the

Telomere

Factors that control how often a cell divides include

Whether the nuclear membrane has broken apart or is intact

During apoptosis caspases

Activate enzymes that cut DNA into same sized pieces

Apoptosis is a form of

Programmed cell death that is a normal part of development

Which sequence of events illustrates the steps of signal transduction

First messenger to receptor molecules to second messenger to cellular response

Proteins that are part of signal transduction pathways in the cell are located in

Cytoplasm and plasm membrane

Cellular adhesion molecules include

Selectins and integrins