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50 Cards in this Set
- Front
- Back
The cellular basis of muscular distrophy is that some of a child’s muscle cells: |
Lack a protein that enables them to withstand the force of contraction |
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A researcher identifies an abnormality in a protein that causes a particular inherited illness. To develop a treatment, it would be helpful to know |
Which cells are affected and how to replace the proteins function in them |
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What does diploid mean? |
Diploid means a pair: body cells have 2 copies of the human genome |
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The approximate number of differentiated cell types in a human body is |
260 |
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Humans belong to what domain? Distinguished by which cells? |
Eukarya Organelles |
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Ribosomes are in the cells of |
All organisms |
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The major macromolecules that make up cells are |
Carbohydrates, proteins, lipids, and nucleic acids |
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About how many average sized bacteria could fit into a human cell? |
1,000 |
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Organelles protect a cell by |
Sequestering bio chemicals that could dismantle other cellular structures |
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The nuclear lamina is: |
A fibrous layer that lines the inner face of the nuclear membrane |
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In a human cell, the genetic material is in the where? |
Nucleus |
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The organelles that contain DNA are the what? |
Nucleus & mitochondrion |
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What is the sequence of events to produce a protein that is secreted? |
A hormone signals the gene that encodes the protein to be transcribed into mRNA in the nucleus. The mRNA is translated into protein on the ER, then processed and folded in the Golgi apparatus, and then sent out of the cell in a vesicle. |
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The organelle that consists of a stack of flat membrane enclosed sacs is the |
Golgi apparatus |
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The organelles that is the equivalent of a cellular garbage disposal system is the |
Lysosome |
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A bubble like structure that ferries molecules such as cholesterol to lysosomes is an |
Endosome |
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In mitochondria |
Energy from nutrients is converted into a form that a cell can use. |
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The cell type with the most mitochondria is |
Muscle |
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Cristae are what |
Membranous structures that are parts of mitochondria |
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In a DNA molecule, the sugar phosphate backbone is the same in everyone but the base sequence is different in everyone. A plasma membrane is similar conceptually to dna in that : |
The lipid belayer is the same in everyone but the nature and pattern of the molecules embedded in it differ |
|
A molecule that binds a cell surface receptor is called a |
Ligand |
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The internal scaffolding of a cell consists of |
Microtubules and microfilamente |
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Cilia are made of what |
Microtubules |
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In hereditary spherocytosis red blood cells lose their doughnut shapes, ballooning out, because they have abnormal |
Ankyrin molecules, which bind spectrum rods to the plasm membranes |
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The cytoskeleton component that consists of different protein types in different cell is |
An intermediate filament |
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The approximate percentage of our cells that are replaced daily is |
10% |
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The 2 major stages of the cell cycle are |
Interphase and mitosis |
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The cell cycle is a series of events a cell Undergoes as it prepares to |
Divide |
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DNA replicates during what phase of the cell cycle? |
S |
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The order of events in the cell cycle is |
G1 to S to G2 to mitosis |
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At the point in the cell cycle when mitosis begins |
Each chromosome consists of two identical chromatids joined at the centromere |
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Chromosomes coil tightly around chromosomal proteins and condense during |
Prophase |
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In which disease is signal transduction abnormal |
Neurofibromatosis type 1 |
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In which disease is cellular adhesion abnormal? |
Arthritis |
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The defining characteristic of a stem cell is |
Self renewal |
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A difference between a stem cell and a progenitor cell is that |
A progenitor cell cannot self-renew and a stem cell can |
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A cell that can divide to give rise to any cell type including those of membranes that support the developing embryo is |
Totipotent |
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An experimental treatment for amyotrophic lateral sclerosis which causes gradual loss of the ability to move sends four genes into cells sampled from a patients skin. This procedure reprograms the cells, which are then exposed to molecules and genes that stimulate them to develop as healthy versions of the cells affected in the disease. These cells are implanted into the patient. They are |
Induced pluripotent stem cells |
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Human embryonic stem cells that are used in research are |
Cultured in laboratory dishes from inner cell mass cells taken from a 5 day embryo |
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Adult stem cells are more accurately called tissue specific or somatic stem cells because |
They are also present at prenatal stages of development |
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Human stem cells are valuable in drug development because they can be used to |
Replace experimental animals such as rats and mice |
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Cells contain twice the normal number of chromosomes briefly during |
Anaphase |
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During S phase replicated chromosomes are joined at their |
Centromeres |
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The part of a chromosome that shortens with each cell division functioning as a clock is the |
Telomere |
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Factors that control how often a cell divides include |
Whether the nuclear membrane has broken apart or is intact |
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During apoptosis caspases |
Activate enzymes that cut DNA into same sized pieces |
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Apoptosis is a form of |
Programmed cell death that is a normal part of development |
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Which sequence of events illustrates the steps of signal transduction |
First messenger to receptor molecules to second messenger to cellular response |
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Proteins that are part of signal transduction pathways in the cell are located in |
Cytoplasm and plasm membrane |
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Cellular adhesion molecules include |
Selectins and integrins |