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56 Cards in this Set

  • Front
  • Back

Alleles

-somatic cells of sexuality: contain pairs of homologous chromosomes (one from mom one from dad)


-different forms of the same gene

Cell Cycle

-Interphase: G1, S-Phase, G2,


-mitosis: prophase, metaphase, anaphase, telophase


-cytokenesis: cytoplasm separates

Chromatin

-a complex of DNA and proteins that forms chromosomes within the nucleus of eukaryotic cells

Daughter Chromosome

-chromosomes that have been separated during mitosis

Gamete

-mature haploid reproduction cell


-ex: egg, sperm

Independent Assortment

-members of a pair ofgenes (alleles) on homologouschromosomes get distributed into gametesindependently of other gene pairs


-occurs during metaphase I of meiosis

Locus

-location of a gene on a chromosome

Neoplasm

-accumulation of abnormally dividing cells


-checkpoint malfunction passed on to descendant cells

S-phase

-Part of Interphase


-Time of synthesis


-Cell copies its DNA (duplicates chromosomes)

Spindle

-temporary structure that moves chromosomes during nuclear division


-made of microtubules

Trisomy

-causes down syndrome when on the 21st chromosome pair

Anaphase

-spindles pull apart the sister chromatids and move them to opposite sides of the cell


-sister chromatids become daughter chromosomes

Cell Plate

-disk-shaped structure that forms during cytokineses in plant cells


-matures into two cell walls, one per cell

Chromosome

-structure that consists of DNA and associated proteins, carries part or all of a cell's genetic information

Malignant Tumor

-cells metastasis and spread to neighboring tissue


-dangerous


-cause cancer

Oncogene

-gene that can transform normal cells into tumor cells

Sexual Replication

-requires fertilization of an egg by sperm


-offspring have a unique combination of genes


-no two offspring have the same genetic material (except twins)

Telomers

-Noncoding DNA sequences that occur at theends of eukaryotic chromosomes


-provide buffer against the loss of more valuable internal DNA


-typical chromosome shortens by 100 nucleotides per division



Tumor

-neoplasm that has formed a lump

Asexual reproduction

-offspring are genetically identical to parent


-no gametes involves

Centromere

-constricted region where sister chromatids attach to each other

Crossing Over

-process by which homologous chromosomes exchange corresponding segments of DNA during prophase I

Genome

-an organisms complete set of genetic material

Interphase

-the interval between mitotic divisions where the cell grows, doubles its cytoplasmic components and replicates its DNA


-cell spends most of its life in this phase


-chromosomes are loosened to allow transcription and DNA replication

Polyploidy

-having three or more of each type of chromosome characteristic in a species

Telophase

-daughter chromosomes reach opposite ends of cell and loosen


-new nuclear envelope develops around each cluster


-spindles dissapear


-cytoplasm prepares to split

Zygote

-cell formed by fusion of two gametes


-ex: an egg that has been fertilized by sperm

Benign Tumor

-cells remain at original site


-typically not dangerous

Centrosome

-the main place where cell microtubules are organized

Cytokenisis

-splitting of cytoplasm


-differs between plant and animal cells


- in plants: cell plate forms

G1 Phase

-Part of Interphase


-interval of growth before DNA replication

Homologous Chromosomes

-chromosomes with the same length, shape and genes that control the same inherited characteristics

Metaphase

-sister chromatids line up in middle of cell

Prophase

-chomosomes begin to pack tightly


-nuclear envelope breaks down


-formation of spindles


-duplicate chromosomes attach to microtubules

Sister chromatids

-the two attached DNA molecules of a duplicated eukaryotic chromosomes

Tetrad

- A group of four chromatids formed from each of a pair of homologous chromosomes that split longitudinally during the prophase I of meiosis.

Cancer

-occurs when a malignant neoplasm physically and metabolically disrupts the body

Checkpoints

-control over the cell cycle


-monitor: -DNA is copied correctly


-nutrient availibilty


- DNA damage

G2 Phase

-Part of Interphase


- interval after DNA replication but before mitosis


-Cell prepares to divide in this phase

Metastisis

-the process in which malignant cells spread from one part of the body to another

Protooncogene

-by mutation, gene can become oncogene

Somatic Cells

-any cell of a living organism other than the reproductive cells.

Translocation

-structural change of a chromosomes in which a broken piece gets reattached in the wrong location

What are the major phases of the cell cycle and what happens during these phases?

-Interphase: G1, S-Phase (DNA synthesis), G2


-Mitosis: Prophase, Metaphase, Anaphase, Telophase


-Cytokenesis

Major stages of Mitosis and what happens during these stages:

-Prophase


-Metaphase


-Anaphase


-Telophase

How many daughter cells result from mitosis?

-2 daughter cells

Understand the significance of mitosis:

-used in asexual reproduction


-growth and development


-cell replacement and repair

How does mitosis in animals differ from mitosis in plants?

-plants have to develop a cell wall before completely dividing

Understand how the cell cycle is controlled and the roll of checkpoints:

-Controlled by checkpoints which check for:


- correct DNA copying


-Any damage to DNA


-enough nutrient availibility to complete process

How is cancer a disease of mitosis?

-Controls that regulate checkpoint genes fail and cells begin to divide uncontrollably

What is the significance of meiosis? What happens at the end of Meiosis I? What happens at the end of Meiosis II?

-

Are the starting cells haploid or diploid? Are the resulting cells haploid or diploid?

-Starting: diploid


-Resulting: haploid

What are the two ways that meiosis can contribute to to genetic variation?

-independent assortment of chromosomes


-crossing over

When does crossing over take place?

-During Prophase I of Meiosis

When does independent assortment of chromosome take place?

-During Metaphase I of Meiosis

What is the diploid number for humans? What is the haploid?

Diploid: 46 chromosomes


Haploid: 23 chromosomes