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33 Cards in this Set

  • Front
  • Back

In fluid mosaic model,why is it called that?

Fluid cause the phospholipids are never static and keep moving.they move in the membrane


Mosaic because the proteins scattered make it look like a mosaic(small pieces make large picec

Feature of fluid mosaic model?

1.membrane is a phospholipid bilayer.


2.phospholipids move around,also separating the layer between from water out and inside(giving cell membrane flexibility)


3.have unsaturated hydrocarbons,the more unsaturated the more fluid phospholipids are. Because they are loosely packed.


5.fluidity is also affected by tail length ,longer the tail lesser the fluidity.


6.two protein types


Intrinsic/integral: embedded in the membrane


When they are fully through spanning it is known as transmembrane


Extrinsic/peripheral :found on the outer and inner surface of the membrane.these are help on the surface by the intrinsic protein or molecule in and out of the cell


Roles of components of the cell membrane?

E

Phospholipids

Cholesterol

Small molecule


Also has hydro phillic and phobic head ,fits easily in lipids


Increase the fluidity at low temp. In membrane bcz it prevents close psckingof phospholipids meaning the cell can survive in cold temp

Glycolipid, glycoproteins,and protein

Glycolipid glycoproteins and protein

Glycolipid Glycoproteins and protein

Glycolipid Glycoproteins and protein

Signalling

Signalling

Signalling

Signalling

Signalling

Signalling

Carrier proteins flip and use energy so have acitve transport

I

Steroid hormones (lipid soluble ) and non polar molecules can easily cross the cell membrane

F

Steps of cell signalling


Signalling molecule:hormone


Receptor:present in on,cytoplasm, nucleus


Cellular activators:2 messenger


Transcription factor


Cellular affects:effect of signalling molecule on the cell


Commons pathway ?

Signalling molecule


Receptor


Cellular response/effect


Exp insulin

Different pathways

Cellular activator:2 messenger


Transcription factor

Pathways of signalling molecule?

Most commons pathway exp insulin

2 pthaway involves cellular activators(2 messenger)

Ion channel patge way signalling

Transcription factor pathways

Diffusion

Diffusion

Diffusion and also facilitated diffusion

Facilitated diffusion

Active transport

Active transport

Bulk tansport

Large material move into or out of cell


Endocytosis


Exocytosis

What happens in a neurone propagation

Stimulus comes ,na v channel and k v channel open allowing na to enter in larger amount and k to leave the cell,after a while this causes the voltage potential to get really low and that's when the k channel open out flow of kLeak Chanel's cause k and na to go out and in the cell respectively,causing the voltage potantial to go down,than the na and pumps cash atp,to maintain it than.when the v approaches -55 mv it opens the gated sodium channel(sensitive to voltage)allowing. Huge amount of sodium to come in.wventually when we move away from the voltage is becomes inactive and close,there is also a k v gated channel which will open when the voltage becomes 30mv,allows passage of k which will go out of cell.In a action graph,the small dent or threshold is reached,so when -55 all sodium goes in and depolarizes the neurone.at 30 mv the k v gated channel become activated causing repolarization ,this causes later the k v gated channel to close causing undershoot which means the voltage is really low but permeability is restored and the leak channels will activate and allow permeability to establish the resting potential .


Na and k pumps and leakage channel help to keep the RESTING ACTION stable ,when a impluse or stimulus comes the gated cell and leakage work